Results 81 to 90 of about 13,277,354 (332)

Toxicological evaluation of standardized Kaempferia parviflora extract: Sub-chronic and mutagenicity studies

Toxicology Reports, 2019
Kaempferia parviflora (KP), also known as Krachai-dam in Thailand, belongs to the family Zingiberaceae and has been used traditionally to improve blood flow and treat inflammatory, allergic, and gastrointestinal disorders. The objective of this study was
Susumu Yoshino, Riyo Awa, Nobuaki Ohto, Yasuo Miyake, Hiroshige Kuwahara   +4 more
doaj  

Xylose Acetals ‐ a New Class of Sustainable Solvents and Their Application in Enzymatic Polycondensation

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Novel organic solvents with an unmodified carbohydrate core were synthesised both from D‐xylose and directly from biomass and were successfully used as reaction media for lipase biocatalysts to synthesise aliphatic and aromatic polyesters. Abstract The use of organic solvents in academic research and industry applications is facing increasing ...
Anastasia O. Komarova, Cicely M. Warne, Hugo Pétremand, Laura König‐Mattern, Johannes Stöckelmaier, Chris Oostenbrink, Georg M. Guebitz, Jeremy Luterbacher, Alessandro Pellis   +8 more
wiley   +1 more source

Closed‐Loop Recyclable Polyhexahydrotriazine Aerogels Utilizing N,N‐Dimethyl Lactamide as a Green Solvent

ChemSusChem, EarlyView.
The synthesis of chemically recyclable polyhexahydrotriazine (PHT) aerogels, using N,N‐dimethyl lactamide, a nontoxic, label‐free solvent, is presented. The PHT aerogels exhibit low bulk density, high porosity, excellent thermal insulation, pronounced thermal stability, and enhanced mechanical performance. Furthermore, PHT aerogels can be depolymerized
Chang‐Lin Wang, Ivona Glišić, Yi‐Ru Chen, Željko Tomović   +3 more
wiley   +1 more source

Quantitative Investigation of Nitrosamine Drug Substance‐Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography–Tandem Mass Spectrometry and Structure–Activity Relationship Analysis

Drug Testing and Analysis, EarlyView.
The study provides information about the impact of physiological gastric conditions on the unbeneficial occurrence of nitrosamine drug substance–related impurities (NDSRIs). Both main factors for nitrosation in the form of acidic conditions and the presence of nitrite were adequately chosen for triggering the conversion of drug compounds into NDSRIs ...
Matthias Vogel, Sylvia E. Escher, Emanuel Weiler, Anke Londenberg, Uwe Deppenmeier, Rhys Whomsley   +5 more
wiley   +1 more source

Further insight into the bioactivity of the freshwater sponge Ochridaspongia rotunda

Pharmaceutical Biology, 2017
Context: Bioprospection has become a dynamic scientific field that explores novel possibilities for the implementation of natural products in medicine and pharmacy.
Aleksandra Talevska, Boris Pejin, Tanja Beric, Slavisa Stankovic   +3 more
doaj   +1 more source

Occurrence and control of genotoxins in drinking water: a monitoring proposal

Journal of Public Health Research, 2016
Many studies have shown the presence of numerous organic genotoxins and carcinogens in drinking water. These toxic substances derive not only from pollution, but also from the disinfection treatments, particularly when water is obtained from surface ...
Elisabetta Ceretti, Massimo Moretti, Ilaria Zerbini, Milena Villarini, Claudia Zani, Silvano Monarca, Donatella Feretti   +6 more
doaj   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Evaluation of the genotoxic potential of ethanolic extracts of stem bark and leaves of Bathysa cuspidata (A.St.-Hil.) Hook

Revista de Ciências Farmacêuticas Básica e Aplicada, 2012
Bathysa cuspidata (A.St.-Hil.) Hook. is a native tree of the Brazilian Atlantic Forest biome, widely used in Brazilian herbal medicine. Despite its widespread use, there is no report as yet regarding the toxicology of this plant.
Douglas Costa Gontijo, Líria Granato Nunes, Carlos Joulbert Alves Souza, Luciano Gomes Fietto, João Paulo Viana Leite   +4 more
doaj   +2 more sources

Evaluation of feasibility of mutagenic testing of shale oil products and effluents.

, 1979
J.L. Epler, T.K. Rao, M.R. Guerin
openalex   +2 more sources

Mutagenicity Testing: A Practical Approach [PDF]

, 1986
S. Venitt, J. M. Parry
openalex   +1 more source