Results 61 to 70 of about 73,569 (303)

Meat-cooking mutagens and risk of renal cell carcinoma

British Journal of Cancer, 2011
Background:High-temperature cooked meat contains two families of carcinogens, heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs). Given the kidneys’ role in metabolism and urinary excretion of these compounds, we investigated meat ...
C. Daniel, K. Schwartz, J. Colt, Linda M. Dong, J. Ruterbusch, M. Purdue, A. Cross, N. Rothman, F. Davis, S. Wacholder, B. Graubard, W. Chow, R. Sinha   +12 more
semanticscholar   +1 more source

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps, Sachin Patel, Kevin Scaife, Toby Holmes, Alica Šoltésová, Sandra Wingaard Thrane, Louise Kristine Vigsnæs, Nigel Baldwin, Christel Jørgensen   +8 more
wiley   +1 more source

Analysis of induced genetic variability for morphological and floral characters with male sterility in sesame (Sesamum indicum L.)

Electronic Journal of Plant Breeding, 2018
Male sterility can be useful to obtain high yielding sesame hybrids with reduced cost and labour. It can be induced artificially into the released cultivars by using chemical mutagens.
M. Imran, M. Dash, T. R. Das and, M. Kabi   +3 more
doaj   +1 more source

Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells. [PDF]

, 1993
A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests.
Schiestl, RH
core   +2 more sources

Efficacy of Haloxyfop‐R‐Methyl on Allium cepa: Cyto‐Genotoxic and In Silico Docking Studies on the Mechanism of Action

Microscopy Research and Technique, EarlyView.
ABSTRACT Haloxyfop‐R‐methyl (HRM) is extensively employed to control annual and perennial grass weeds. This study aimed to investigate the cyto‐genotoxic effects of HRM at concentrations of 1.19, 2.38, and 4.76 mg/L over various time intervals (24, 48, 72, and 96 h) on Allium cepa root.
Recep Liman, Emine Kılıç, Erman Salih İstifli, Yudum Yeltekin Uğur, İbrahim Hakkı Ciğerci   +4 more
wiley   +1 more source

EFFECT OF ETHYL METHANESULFONATE (EMS) AND N-NITROSE-N´-ETHYL UREA (ENU) ON CALLUS GROWTH OF COMMON BEAN [PDF]

Journal of Central European Agriculture, 2005
Infl uence of ethyl methanesulfonate (EMS) and N-nitrose-N´-ethyl urea (ENU) mutagenic treatments was investigated on three time sub-cultured calli obtained from leaf petiole explants of 7-day old sterile plants.
Diana Lilova SVETLEVA, Paola CRINÓ
doaj  

Ethyl Methanesulfonate (EMS) Mutagen Toxicity-Induced DNA Damage, Cytosine Methylation Alteration, and iPBS-Retrotransposon Polymorphisms in Wheat (Triticum aestivum L.)

Agronomy, 2023
The use of mutagens in plant breeding is used to create new germplasm, increase agricultural yield, quality, and resistance to diseases and pests. Mutagens are physical or chemical factors that can alter the DNA or RNA structure of an organism, causing ...
Aras Türkoğlu, Kamil Haliloğlu, Metin Tosun, Henryk Bujak, Barış Eren, Fatih Demirel, Piotr Szulc, Halit Karagöz, Marek Selwet, Güller Özkan, Gniewko Niedbała   +10 more
doaj   +1 more source

Environmental mutagens may be implicated in the emergence of drug-resistant microorganisms.

FEMS Microbiology Letters, 2011
The emergence of drug-resistant microorganisms is an important medical and social problem. Drug-resistant microorganisms are thought to grow selectively in the presence of antibiotics. Most clinically isolated drug-resistant microorganisms have mutations
Emiko Miyahara, Makiko Nishie, Shota Takumi, H. Miyanohara, J. Nishi, K. Yoshiie, H. Oda, M. Takeuchi, M. Komatsu, Kohji Aoyama, M. Horiuchi, T. Takeuchi   +11 more
semanticscholar   +1 more source

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals. [PDF]

, 2019
A database of 91 chemicals with published data from both transgenic rodent mutation (TGR) and rodent comet assays has been compiled. The objective was to compare the sensitivity of the two assays for detecting genotoxicity.
Aardema, MJ, Beevers, C, Bhalli, J, Douglas, GR, Escobar, PA, Farabaugh, CS, Guerard, M, Johnson, GE, Kirkland, D, Kulkarni, R, Le Curieux, F, LeBaron, MJ, Levy, DD, Long, AS, Lott, J, Lovell, DP, Luijten, M, Marchetti, F, Nicolette, JJ, Pfuhler, S, Roberts, DJ, Stankowski, LF, Thybaud, V, Weiner, SK, Williams, A, Witt, KL, Young, R   +26 more
core   +3 more sources

Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy

Small Science, EarlyView.
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri, Rodolfo Villa, Ya‐Ping Shiau, Menghuan Tang, Kelsey Jane Racacho, Qiufang Zong, Saiful Islam Chowdhury, Tan Hua, Felipe Godinez, Andrew Birkeland, Tzu‐Yin Lin, Yuanpei Li   +11 more
wiley   +1 more source