Results 1 to 10 of about 1,085,673 (100)

Proinflammatory activation of microglia in the cerebellum hyperexcites Purkinje cells to trigger ataxia

open access: yesPharmacological Research, 2023
Specific medications to combat cerebellar ataxias, a group of debilitating movement disorders characterized by difficulty with walking, balance and coordination, are still lacking.
Shu-Tao Xie   +18 more
doaj   +1 more source

Three-Dimensional X-ray Imaging of β-Galactosidase Reporter Activity by Micro-CT: Implication for Quantitative Analysis of Gene Expression

open access: yesBrain Sciences, 2021
Acquisition of detailed anatomical and molecular knowledge from intact biological samples while preserving their native three-dimensional structure is still a challenging issue for imaging studies aiming to unravel a system’s functions. Three-dimensional
Olga Ermakova   +12 more
doaj   +1 more source

An entropy-based method to measure phase-locking between LFP and spikes

open access: yesAIP Advances, 2023
Phase-locking between local field potential and spikes has been widely investigated through neurophysiological analysis. Two indices most frequently adopted traditionally include the mean resultant length and p of the Rayleigh test.
Xing-Yan Dang   +6 more
doaj   +1 more source

The contribution of maternal oral, vaginal, and gut microbiota to the developing offspring gut

open access: yesScientific Reports, 2023
There is limited understanding of how the microbiota colonizing various maternal tissues contribute to the development of the neonatal gut microbiota (GM). To determine the contribution of various maternal microbiotic sites to the offspring microbiota in
Amber L. Russell   +6 more
doaj   +1 more source

HOE DOORDACHT OM TE GAAN MET ETHISCHE VRAAGSTUKKEN?

open access: yesJournal of Social Intervention, 2020
“Als sociaal werker word je, bij de uitoefening van je vak, onvermijdelijk geconfronteerd met te nemen beslissingen. Beslissingen die niet enkel gestoeld zijn op theoretische inzichten, methodische ervaringen, correcte toepassingen van regels en codes ...
Fuusje de Graaff
doaj   +1 more source

BOEKBESPREKING DE ONGEKENDE MOGELIJKHEID VAN HET ALLEDAAGSE

open access: yesJournal of Social Intervention, 2019
Als docent van een HBO sociaal werk beoordeel ik veel eindstukken van studenten die van hun opdrachtgever de vraag kregen te onderzoeken hoe zij de sociale participatie van ouderen, jongeren, laaggeletterden, migranten of mensen met een beperking konden ...
Fuusje de Graaff
doaj   +1 more source

Functional loss of Ccdc151 leads to hydrocephalus in a mouse model of primary ciliary dyskinesia

open access: yesDisease Models & Mechanisms, 2019
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder affecting normal structure and function of motile cilia, phenotypically manifested as chronic respiratory infections, laterality defects and infertility.
Francesco Chiani   +7 more
doaj   +1 more source

Isolation of segmented filamentous bacteria from complex gut microbiota

open access: yesBioTechniques, 2015
Segmented filamentous bacteria (SFB) modulate the ontogeny of the immune system, and their presence can significantly affect mouse models of disease. Until recently, the inability to successfully culture SFB has made controlled studies on the mechanisms ...
Aaron C. Ericsson   +7 more
doaj   +1 more source

Beelden van de professional

open access: yesJournal of Social Intervention, 2016
Ed de Jonge. Beelden van de Professional. Inspiratiebronnen voor professionalisering. Delft: Eburon, 2015, 409 p., €35,00.
Fuusje de Graaff
doaj   +1 more source

Effect of Shipping on the Microbiome of Donor Mice Used to Reconstitute Germ-Free Recipients

open access: yesGut Microbes Reports
The gut microbiome (GM) influences multiple processes during host development and maintenance. To study these events, fecal microbiota transfer (FMT) to germ-free (GF) recipients is often performed.
Zachary L. McAdams   +7 more
doaj   +1 more source

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