Results 1 to 10 of about 2,159,794 (237)
Distinguishing Mutant knots [PDF]
Journal of Geometry and Physics, 2021 Knot theory is actively studied both by physicists and mathematicians as it provides a connecting centerpiece for many physical and mathematical theories. One of the challenging problems in knot theory is distinguishing mutant knots. Mutant knots are not distinguished by colored HOMFLY-PT polynomials for knots colored by either symmetric and or ...
L. Bishler +8 more
openaire +3 more sources
Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs. [PDF]
, 2012 Mutation of the tumor suppressor p53 plays a major role in human carcinogenesis. Here we describe gene-targeted porcine mesenchymal stem cells (MSCs) and live pigs carrying a latent TP53(R167H) mutant allele, orthologous to oncogenic human mutant TP53 ...
Durkovic, Marina +13 more
core +14 more sources
Pharmacological Research, 2023 Specific medications to combat cerebellar ataxias, a group of debilitating movement disorders characterized by difficulty with walking, balance and coordination, are still lacking.
Shu-Tao Xie +18 more
doaj +1 more source
Brain Sciences, 2021 Acquisition of detailed anatomical and molecular knowledge from intact biological samples while preserving their native three-dimensional structure is still a challenging issue for imaging studies aiming to unravel a system’s functions. Three-dimensional
Olga Ermakova +12 more
doaj +1 more source
An entropy-based method to measure phase-locking between LFP and spikes
AIP Advances, 2023 Phase-locking between local field potential and spikes has been widely investigated through neurophysiological analysis. Two indices most frequently adopted traditionally include the mean resultant length and p of the Rayleigh test.
Xing-Yan Dang +6 more
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The contribution of maternal oral, vaginal, and gut microbiota to the developing offspring gut
Scientific Reports, 2023 There is limited understanding of how the microbiota colonizing various maternal tissues contribute to the development of the neonatal gut microbiota (GM). To determine the contribution of various maternal microbiotic sites to the offspring microbiota in
Amber L. Russell +6 more
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Cell Discovery, 2022 Neonatal heart undergoes metabolic conversion and cell cycle arrest preparing for the increased workload during adulthood. Herein, we report that neonatal ketone body elevation is a critical regulatory factor for postnatal heart development.
Danyang Chong +16 more
doaj +1 more source
Characterisation of a pucBA deletion mutant from Rhodopseudomonas palustris lacking all but the pucBAd genes [PDF]
, 2017 Rhodopseudomonas palustris is a species of purple photosynthetic bacteria that has a multigene family of puc genes that encode the alpha and beta apoproteins, which form the LH2 complexes.
Carey, Anne-Marie +8 more
core +1 more source
Functional loss of Ccdc151 leads to hydrocephalus in a mouse model of primary ciliary dyskinesia
Disease Models & Mechanisms, 2019 Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder affecting normal structure and function of motile cilia, phenotypically manifested as chronic respiratory infections, laterality defects and infertility.
Francesco Chiani +7 more
doaj +1 more source
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials [PDF]
, 2006 Recent studies suggest that the toxicity of familial amyotrophic lateral sclerosis mutant Cu, Zn superoxide dismutase (SOD1) arises from its selective recruitment to mitochondria. Here we demonstrate that each of 12 different familial ALS-mutant SOD1s
Butler Gralla, Edith +8 more
core +2 more sources