Results 91 to 100 of about 2,828,087 (336)
Empirical Evaluation of Mutation-based Test Prioritization Techniques
, 2018 We propose a new test case prioritization technique that combines both mutation-based and diversity-based approaches. Our diversity-aware mutation-based technique relies on the notion of mutant distinguishment, which aims to distinguish one mutant's ...
Bae, Doo-Hwan +3 more
core +2 more sources
Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers. [PDF]
, 2020 Tumor-associated p53 mutations endow cells with malignant phenotypes, including chemoresistance. Amyloid-like oligomers of mutant p53 transform this tumor suppressor into an oncogene.
de Oliveira, Guilherme AP +8 more
core +1 more source
AKT-mTOR signaling-mediated rescue of PRKAG2 R302Q mutant-induced familial hypertrophic cardiomyopathy by treatment with β-adrenergic receptor (β-AR) blocker metoprolol [PDF]
, 2022 Jian Zhuo +5 more
openalex +1 more source
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Parasites & Vectors, 2012 Background Parasites of the Leishmania genus alternate between the flagellated extracellular promastigote stage and intracellular amastigotes. Here we report the characterization of a Leishmania isolate, obtained from a cutaneous leishmaniasis patient ...
Zauli Rogéria C +15 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2020 Male sterility has been widely used in hybrid seed production in Brassica, but not in B. rapa ssp. chinensis, and genetic models of male sterility for this subspecies are unclear. We discovered a spontaneous mutant in B. rapa ssp. chinensis.
Tzu-Kai Lin, Ya-Ping Lin, Shun-Fu Lin
doaj +1 more source
Molecular and physiological analysis of flag leaf senescence and remobilization of assimilates in bread wheat under terminal drought stress [PDF]
مجله بیوتکنولوژی کشاورزی, 2017 In the physiological study of stem remobilization of assimilates during grain filling, mutant genetic materials are a valuable tool. Two advanced mutant lines of bread wheat (T-67-60 and T-65-7-1) along with their wild type (Tabasi Cv.) were planted at ...
saed bagherikia +4 more
doaj +1 more source
Journal of Molecular Cell Biology, 2018 The accumulation of genetic alterations in driver genes is responsible for the development and malignant progression of colorectal cancer. Comprehensive genome analyses have revealed the driver genes, including APC, KRAS, TGFBR2, and TP53, whose ...
M. Nakayama, M. Oshima
semanticscholar +1 more source
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Plants, 2020 Kenaf is a source of fiber and a bioenergy crop that is considered to be a third world crop. Recently, a new kenaf cultivar, "Jangdae," was developed by gamma irradiation.
Jae Il Lyu +11 more
doaj +1 more source