Results 191 to 200 of about 2,159,893 (336)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Inhibition of GPX4 induces the death of p53-mutant triple-negative breast cancer cells. [PDF]
Breast Cancer Res TreatTahaney WM +11 more
europepmc +1 more source
OA08.03 MET Copy Number Gain Associates with Gefitinib Resistance in Leptomeningeal Carcinomatosis of EGFR Mutant Lung Cancer [PDF]
, 2017 Seiji Yano +7 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
T $$ {}_{1\rho } $$ as a Biomarker for IDH1 Mutation Status in a Glioma Mouse Model. [PDF]
NMR BiomedEhler HJS +4 more
europepmc +1 more source
Resurrection of Flagellar Bending Movements in Chlamydomonas Paralyzed Mutants at High Pressure [PDF]
, 2017 Toshiki Yagi, Masayoshi Nishiyama
openalex +1 more source