Results 201 to 210 of about 2,828,087 (336)

A Unifying Mechanism for Shared Splicing Aberrations in Splicing Factor Mutant Cancers [PDF]

Prajwal Boddu, Rahul Roy, Stephan Hütter, Francis Baumgartner, Wenxue Li, Gabriele Todisco, Francesca Ficara, M. Porta, Yansheng Liu, Torsten Haferlach, Manoj M. Pillai   +10 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Correction: TSG101 depletion dysregulates mitochondria and PML NBs, triggering MAD2-overexpressing interphase cell death (MOID) through AIFM1-PML-DAXX pathway

Cell Death and Disease
Yao Xi, Rui Xu, Shengnan Chen, Jiezhu Fang, Xiang Duan, Yidan Zhang, Guoli Zhong, Zhifei He, Yan Guo, Xinyu Li, Wenzhi Tao, Yang Li, Yan Li, Lei Fang, Yohei Niikura   +14 more
doaj   +1 more source

Observations Concerning Rhizobium tropici Bacteroid Phosphorus Stress Response During Symbiosis With Phaseolus vulgaris. [PDF]

Environ Microbiol Rep
Botero LM, Al-Niemi T, McDermott TR.
europepmc   +1 more source

Targeting Dual-Impact FBXO7 Mutants Implicated in Parkinson’s Disease and Cancer: An Integrated Approach Using Density Functional Theory, Molecular Docking, and Molecular Dynamics [PDF]

Maryam Ebrahimi, Foad Rezaeifar, Saba Mojezati, Mobina Moradi, Mahdi Alijanianzadeh   +4 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Structural and allosteric effects of the membrane-bound PI3Kα H1047R mutation and opportunities for drug discovery. [PDF]

Commun Chem
Kotzampasi DM, Cournia Z.
europepmc   +1 more source

Mutational Analysis of All Conserved Basic Amino Acids in RAG-1 Reveals Catalytic, Step Arrest, and Joining-Deficient Mutants in the V(D)J Recombinase [PDF]

, 2002
Leslie E. Huye, Mary M. Purugganan, Ming‐Ming Jiang, David B. Roth   +3 more
openalex   +1 more source

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

Science, 2015
Jihye Yun, Edouard Mullarky, Changyuan Lu, Kaitlyn N. Bosch, A. Kavalier, Keith D. Rivera, Jatin Roper, I. I. C. Chio, Eugenia G. Giannopoulou, C. Rago, A. Muley, J. Asara, J. Paik, O. Elemento, Zhengming Chen, D. Pappin, L. Dow, N. Papadopoulos, S. Gross, L. Cantley   +19 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source