Results 211 to 220 of about 2,114,568 (336)

Partners in root nodule symbiosis respond uniquely to heavy metal stresses in a host genotype-dependent manner. [PDF]

Sci Rep
Chakraborty S, Sharma R, Bhat A, Curtin SJ, Wen J, Mysore KS, Paape T.   +6 more
europepmc   +1 more source

A MICROBIOLOGICAL METHOD FOR THE DETERMINATION OF CHOLINE BY USE OF A MUTANT OF NEUROSPORA

, 1943
N. H. Horowitz, G. W. Beadle
openalex   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

GhAOS integrates circadian rhythm and jasmonic acid signaling to regulate high temperature stress responses in cotton and Arabidopsis. [PDF]

BMC Biol
Khan AH, Li Q, Luo A, Ma H, Kiedrzyński M, Shalmani A, Akbar A, Iqbal A, Cao J, Zhu L, Zhang X, Min L.   +11 more
europepmc   +1 more source

RECOMBINATIONS OF MUTANT PHAGES OF BACILLUS MEGATHERIUM 899A [PDF]

, 1953
James S. Murphy
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PD-L1 regulates c-MET phosphorylation and contributes to MET-dependent resistance to osimertinib in EGFR-mutant NSCLC. [PDF]

J Biomed Sci
Hsu CC, Huang DD, Hsu WH, Hsieh MS, Lin FY, Tai PC, Chou SY, Tsai HH, Tseng CY, Liao BC, Shih JY, Yang JC.   +11 more
europepmc   +1 more source

THE PROPORTION OF MUTANTS IN BACTERIAL CULTURES [PDF]

, 1957
John H. Northrop, M. Kunitz
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Efficient mathematical methodology to determine multistep mutant burden in spatially growing cell populations. [PDF]

PNAS Nexus
Komarova NL, Pritchard JR, Wodarz D.
europepmc   +1 more source