The LysR-family transcriptional regulator VtlR coordinates carbon metabolism, oxidative and nitrosative stress resistance, and virulence in Brucella melitensis. [PDF]
Wang Y +10 more
europepmc +1 more source
Homologous recombination mutant lethality differs between h− and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin [PDF]
Peter Kolesár +3 more
openalex +1 more source
Characterization of cis‐acting prgQ mutants: evidence for two distinct repression mechanisms by Qa RNA and PrgX protein in pheromone‐inducible enterococcal plasmid pCF10 [PDF]
Taeok Bae +2 more
openalex +1 more source
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
M. Arrasate +4 more
semanticscholar +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Mutational landscape of gastrointestinal stromal tumors using next-generation sequencing of a 73-gene panel. [PDF]
Wang C +10 more
europepmc +1 more source
Exploratory analysis of lamivudine legacy and clonal selection of HBs truncation mutants in HBV-related hepatocellular carcinoma [PDF]
Yu‐De Chu +5 more
openalex +1 more source
Different Proteolipid Protein Mutants Exhibit Unique Metabolic Defects [PDF]
Maik Hüttemann +7 more
openalex +1 more source
Mutant p53 in Cancer: New Functions and Therapeutic Opportunities
P. Muller, K. Vousden
semanticscholar +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source

