Results 211 to 220 of about 2,828,087 (336)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Mutational landscape of gastrointestinal stromal tumors using next-generation sequencing of a 73-gene panel. [PDF]

open access: yesWorld J Surg Oncol
Wang C   +10 more
europepmc   +1 more source

Exploratory analysis of lamivudine legacy and clonal selection of HBs truncation mutants in HBV-related hepatocellular carcinoma [PDF]

open access: gold
Yu‐De Chu   +5 more
openalex   +1 more source

Different Proteolipid Protein Mutants Exhibit Unique Metabolic Defects [PDF]

open access: gold, 2009
Maik Hüttemann   +7 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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