Results 211 to 220 of about 1,179,318 (342)

THE PROPORTION OF MUTANTS IN BACTERIAL CULTURES [PDF]

, 1957
John H. Northrop, M. Kunitz
openalex   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source

Dual ASXL1 and CSF3R mutations drive myeloid-biased stem cell expansion and enhance neutrophil differentiation. [PDF]

Blood Adv
Darmusey L, Bagley AJ, Nguyen TT, Carlson HL, Blaylock H, Shrestha SB, Pang A, Tauchmann S, Taylor SC, Foley AC, Niño KE, Pietras EM, Braun TP, Maxson JE.   +13 more
europepmc   +1 more source

The Isolation and Characterization of Heat-Resistant Mutants of the Najarian Strain of NDV [PDF]

, 1955
Elise Cahn Goldman, R. P. Hanson
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Prevalence of MTHFR C677T polymorphism and its association with serum homocysteine and blood pressure among different ethnic groups: insights from a cohort study of Nepal. [PDF]

BMC Cardiovasc Disord
Bhatt RD, Karmacharya BM, Shrestha A, Timalsena D, Madhup S, Shahi R, Katuwal N, Shrestha R, Fitzpatrick AL, Risal P.   +9 more
europepmc   +1 more source

Genética de Coffea XXIV - Mutantes de Coffea arabica procedemtes da Etiópia [PDF]

, 1959
Alcides Carvalho
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Pasteurella multocida filamentous hemagglutinin B1 (fhaB1) gene is not involved with avian fowl cholera pathogenesis in turkey poults. [PDF]

BMC Vet Res
Dassanayake RP, Briggs RE, Kaplan BS, Menghwar H, Kanipe C, Casas E, Tatum FM.   +6 more
europepmc   +1 more source

A Mutant of Drosophila Melanogaster Resembling the So-Called Unstable Genes of Drosophila Virilis [PDF]

, 1943
Richard Goldschmidt
openalex   +1 more source