Results 31 to 40 of about 2,828,087 (336)

Towards a TILLING platform for functional genomics in Piel de Sapo melons

open access: yesBMC Research Notes, 2011
Background The availability of genetic and genomic resources for melon has increased significantly, but functional genomics resources are still limited for this crop.
Pujol Marta   +10 more
doaj   +1 more source

Genetically modified mice for research on human diseases: A triumph for Biotechnology or a work in progress?

open access: yesThe EuroBiotech Journal, 2022
Genetically modified mice are engineered as models for human diseases. These mouse models include inbred strains, mutants, gene knockouts, gene knockins, and ‘humanized’ mice.
Brown Richard E.
doaj   +1 more source

Transient disappearance of RAS mutant clones in plasma: A counterintuitive clinical use of EGFR inhibitors in RAS mutant metastatic colorectal cancer [PDF]

open access: yes, 2019
Genomic studies performed through liquid biopsies widely elucidated the evolutionary trajectory of RAS mutant clones under the selective pressure of EGFR inhibitors in patients with wild type RAS primary colorectal tumors. Similarly, the disappearance of
Belardinilli, Francesca   +9 more
core   +1 more source

Forward Genetics by Sequencing EMS Variation-Induced Inbred Lines

open access: yesG3: Genes, Genomes, Genetics, 2017
In order to leverage novel sequencing techniques for cloning genes in eukaryotic organisms with complex genomes, the false positive rate of variant discovery must be controlled for by experimental design and informatics.
Charles Addo-Quaye   +5 more
doaj   +1 more source

Influence of UV light exposure on mineral composition and biomass production of mycomeat produced from different agricultural substrates [PDF]

open access: yesJournal of Agricultural Sciences (Belgrade), 2017
The wild and mutant strain of Pleurotus sajor caju was cultured on different agricultural substrates. Treatment 1 contained agricultural substrates alone. Treatment 2 contained the mutant strain of the mushroom plus agricultural waste. Treatment
Adejumo Isaac Oluseun   +2 more
doaj   +1 more source

Mutant knots and intersection graphs [PDF]

open access: yes, 2007
We prove that if a finite order knot invariant does not distinguish mutant knots, then the corresponding weight system depends on the intersection graph of a chord diagram rather than on the diagram itself.
Chmutov   +9 more
core   +3 more sources

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

open access: yesNature Genetics, 2017
A widespread approach to modern cancer therapy is to identify a single oncogenic driver gene and target its mutant-protein product (for example, EGFR-inhibitor treatment in EGFR-mutant lung cancers).
C. Blakely   +28 more
semanticscholar   +1 more source

Deletion of N-acetylmuramyl-L-alanine amidases alters the host immune response to Mycobacterium tuberculosis infection

open access: yesVirulence, 2021
Peptidoglycan (PG), a heteropolysaccharide component of the mycobacterial cell wall can be shed during tuberculosis infection with immunomodulatory consequences.
Nathan Scott Kieswetter   +7 more
doaj   +1 more source

Isolation and pathogenic characterization of duck adenovirus 3 mutant circulating in China

open access: yesPoultry Science, 2022
: Duck adenoviruses (DAdVs) include serotype 1 (DAdV-1) in the genus Atadenovirus and serotypes 2-4 (DAdV-2, 3, and 4) in the genus Aviadenovirus. DAdV-3 was initially isolated from Chinese Muscovy ducks in 2014, whereby the infected ducks exhibited ...
Xinjin Shi   +8 more
doaj   +1 more source

Evolutionary dynamics and fixation probabilities in directed networks

open access: yes, 2009
We investigate the evolutionary dynamics in directed and/or weighted networks. We study the fixation probability of a mutant in finite populations in stochastic voter-type dynamics for several update rules.
Masuda, Naoki, Ohtsuki, Hisashi
core   +1 more source

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