Results 31 to 40 of about 2,088,899 (353)
NHEJ protects mycobacteria in stationary phase against the harmful effects of desiccation [PDF]
, 2007 The physiological role of the non-homologous end-joining (NHEJ) pathway in the repair of DNA double-strand breaks (DSBs) was examined in Mycobacterium smegmatis using DNA repair mutants (DeltarecA, Deltaku, DeltaligD, Deltaku/ligD, DeltarecA/ku/ligD ...
Brzostek, A. +5 more
core +1 more source
Unbalanced overexpression of the mutant allele in murine Patched mutants [PDF]
Carcinogenesis, 2002 Inherited mutations of Patched (PTCH) in the nevoid basal cell carcinoma syndrome (NBCCS) lead to several developmental defects and contribute to tumor formation in a variety of tissues. PTCH mutations have been also identified in sporadic tumors associated with NBCCS including basal cell carcinoma (BCC) and medulloblastoma.
Calzada-Wack, J. +8 more
openaire +5 more sources
Genetic Dissection of the Drosophila Nervous System by means of Mosaics [PDF]
, 1970 Given a mutant having abnormal behavior, the anatomical domain responsible for the deficit may be identified by the use of genetic mosaicism. Individuals may be produced in which a portion of the body is mutant male while the rest is normal female.
Benzer, Seymour, Hotta, Yoshiki
core +1 more source
Pharmacological Research, 2023 Specific medications to combat cerebellar ataxias, a group of debilitating movement disorders characterized by difficulty with walking, balance and coordination, are still lacking.
Shu-Tao Xie +18 more
doaj
Isolation of segmented filamentous bacteria from complex gut microbiota
BioTechniques, 2015 Segmented filamentous bacteria (SFB) modulate the ontogeny of the immune system, and their presence can significantly affect mouse models of disease. Until recently, the inability to successfully culture SFB has made controlled studies on the mechanisms ...
Aaron C. Ericsson +7 more
doaj +1 more source
A ClpB Chaperone Knockout Mutant of Mesorhizobium ciceri Shows a Delay in the Root Nodulation of Chickpea Plants [PDF]
, 2012 Several molecular chaperones are known to be involved in bacteria stress response. To investigate the role of chaperone ClpB in rhizobia stress tolerance as well as in the rhizobiaplant symbiosis process, the clpB gene from a chickpea microsymbiont ...
Brígido, Clarisse +4 more
core +1 more source
Mutant ADA2 in Vasculopathies [PDF]
New England Journal of Medicine, 2014 n engl j med 371;5 nejm.org july 31, 2014 478 CRT-D between patients with ischemic cardiomyopathy with NYHA class I or class II and patients with nonischemic cardiomyopathy. Hazard ratios were similar in these groups (0.66, 0.65, and 0.57, respectively), which denoted a similar effect size.
Rita Guerreiro +2 more
openaire +9 more sources
Phenotypic mixing and hiding may contribute to memory in viral quasispecies [PDF]
, 2003 Background. In a number of recent experiments with food-and-mouth disease virus, a deleterious mutant, was found to avoid extinction and remain in the population for long periods of time. This observation was called quasispecies memory.
Novella, Isabel S., Wilke, Claus O.
core +4 more sources
The improvement of early maturity red rice mutant trait for drought tolerance
International Journal of Plant Biology, 2017 Accession of red rice does not have the traits of early maturity, drought tolerance and high yield. Mutation is needed to obtain the desired genetic resources.
Eries D. Mustikarini +3 more
doaj +1 more source
Invariants of genus 2 mutants [PDF]
, 2007 Pairs of genus 2 mutant knots can have different Homfly polynomials, for example some 3-string satellites of Conway mutant pairs. We give examples which have different Kauffman 3-variable polynomials, answering a question raised by Dunfield et al in ...
H. R. MORTON +2 more
core +3 more sources