Results 51 to 60 of about 5,812 (165)

Influence of Translation Initiation on Organellar Protein Targeting in Arabidopsis [PDF]

, 2004
A primary focus of the Mackenzie laboratory is the elucidation of processes and machinery for mitochondrial genome maintenance and transmission in higher plants.
Mackenzie, Sally A.
core   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

Implementation of a lynch syndrome screening protocol on colorectal cancer patients 70 years of age and under: the initial Manitoba screening experience [PDF]

, 2017
Objective: Assess the ability of a Manitoba instituted Lynch Syndrome (LS), an autosomal dominant cancer syndrome, screening protocol to identify carriers in colorectal cancer (CRC) patients as compared to literature.
Sexsmith, Laura
core  

Identification of protein expression signatures in gastric carcinomas using clustering analysis [PDF]

, 2012
Background and Aim: The identification of gastric carcinomas (GC) has traditionally been based on histomorphology. Recently, DNA microarrays have successfully been used to identify tumors through clustering of the expression profiles.
Torres, Cesar, Brentani, Helena Paula, Costa, Wilson Luiz, Jr., Soares, Fernando A., Begnami, Maria D., Nonogaki, Suely, Montagnini, Andre, Fregnani, Jose Humberto T. G.   +7 more
core   +1 more source

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

Analysis of the transcriptional program governing meiosis and gametogenesis in yeast and mammals [PDF]

, 2006
During meiosis a competent diploid cell replicates its DNA once and then undergoes two consecutive divisions followed by haploid gamete differentiation.
Schlecht, Ulrich
core   +1 more source

A new subtype of Lynch syndrome associated with MSH2 c.354T>A (p. Y118*) identified in a Chinese family: case report and literature review

Frontiers in Genetics
BackgroundLynch syndrome (LS) is an autosomal dominant inherited disorder caused by mutations in mismatch repair genes. Genetic counseling is crucial for the prevention and treatment of LS, as individuals with these mutations have an increased lifetime ...
Lan Zhong, Lan Zhong, Wenxiang Wang, Wenxiang Wang, Wenxiang Wang, Yuanqiong Duan, Yuanqiong Duan, Liang Song, Liang Song, Zhanghuan Li, Kaixuan Yang, Qintong Li, Rutie Yin, Rutie Yin   +13 more
doaj   +1 more source

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

Phylogenetic analyses of Sarcophyton species and relationship with chemotypes. [PDF]

, 2012
Phylogentetic tree of an alignment of utilizing mitochondrial protein-coding genes MutS homolog msh1 sequences for Sarcophyton specimens constructed by the maximum likelihood (ML) method. Values at branches represent ML, neighbor-joining (NJ) and maximum
Satoe Aratake (187735), Yuichi Kawanishi (187744), Ryuichi Shinjo (187750), Tomohiko Tomura (187737), James Davis Reimer (187755), Hideaki Maekawa (187758), Junichi Tanaka (39484), Seikoh Saitoh (187739), Ryouma Yokokura (187741)   +8 more
core   +1 more source

An In‐Silico Study to Identify Relevant Biomarkers in Sepsis Applying Integrated Bulk RNA Sequencing and Single‐Cell RNA Sequencing Analyses

Global Challenges
This study aims to discover sepsis‐related biomarkers via in‐silico analyses. The single‐cell sequencing RNA (sc‐RNA) data and metabolism‐related genes are obtained from public databases and previous studies, respectively.
Qile Ye, Yuhang Dong, Jingting Liang, Jingyao Lv, Rong Tang, Shuai Zhao, Guiying Hou   +6 more
doaj   +1 more source