Results 61 to 70 of about 5,812 (165)

The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics

Clinical Genetics, EarlyView.
The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree, Mark J. Arends, Joseph D. Khoury, Erika R. E. Denton, Anthony J. Gill, Alexander J. Lazar, Ian M. Frayling, Stefan M. Pfister, Mark A. Rubin, Katia R. M. Leite, Raymond Dalgleish, Elspeth A. Bruford, Sharon E. Plon, Ada Hamosh, Michael Francis Walsh, Gabrielle Goldman‐Lévy, Harshima Wijesinghe, William D. Foulkes, Dilani Lokuhetty   +18 more
wiley   +1 more source

A cytochrome P450 gene, GmSUR2a, confers submergence tolerance and improves yield in soybean by modulating auxin homeostasis

Journal of Integrative Plant Biology, EarlyView.
The key cytochrome P450 gene GmSUR2a enables soybeans to withstand destructive submergence stress. By lowering the level of the plant hormone indole‐3‐acetic acid, this gene improves soybean survival and increases field yield. It offers an important tool for breeding stress‑resilient soybeans, securing food production against extreme weather conditions.
Yangyang Chen, Pingzhang Feng, Mengwei Zheng, Lipei Zhao, Yi Li, Yali Jing, Yisa Wang, Bo Zhang, Changzhong Liu, Chengyu Wei, Jijun Yan, Jinfang Chu, Shanshan Chu, Erhui Xiong, Yongqing Jiao   +14 more
wiley   +1 more source

Evidence for breast cancer as an integral part of Lynch syndrome [PDF]

, 2012
Lynch syndrome, an autosomal dominant cancer predisposition caused by mutations in DNA mismatch repair (MMR) genes, mainly mainly mutL homolog 1, OMIM 120436 (MLH1) and mutS homolog 2, OMIM 609309 (MSH2), encompasses a tumor spectrum including primarily ...
Mueller, Hansjakob, Kovac, Michal, Buser, Mauro, Marra, Giancarlo, Marra, Giancarlo; https://orcid.org/, Gautier, Lucienne, Heinimann, Karl, Buerki, Nicole   +7 more
core   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Association Between Microsatellite Instability Status, Clinicopathological Features and Mitochondrial DNA Amplification in Patients With Colorectal Cancer [PDF]

The relationship between BRAF-V600E mutations, mitochondrial DNA amplification and microsatellite instability-high (MSI-H) in colorectal cancer (CRC) has yet to be fully elucidated.
Chen, Xi, Lu, Junmi, Tong, Zhongyi, Tan, Hong, Guo, Tao   +4 more
core   +2 more sources

Cadmium stress alters gene expression of DNA mismatch repair related genes in Arabidopsis seedlings [PDF]

, 2008
Cadmium (Cd) is a non essential element, and is a widespread environmental pollutant. Exposure to Cd can result in a variety of adverse health effects in plant and humans.
Francis, Dennis, Yang, Yuesuo, Rogers, Hilary Joan, Zhang, Q., Liu, W.   +4 more
core   +1 more source

DNA demethylation is involved in nitric oxide-induced flowering in tomato

Journal of Integrative Agriculture
Flowering is one of the most important phenological periods, as it determines the timing of fruit maturation and seed dispersal. To date, both nitric oxide (NO) and DNA demethylation have been reported to regulate flowering in plants.
Xuemei Hou, Meimei Shi, Zhuohui Zhang, Yandong Yao, Yihua Li, Changxia Li, Wenjin Yu, Chunlei Wang, Weibiao Liao   +8 more
doaj   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, Volume 269, Issue 4-5, Page 387-398, August 2026.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Loss of CDX2 gene expression is associated with DNA repair proteins and is a crucial member of the Wnt signaling pathway in liver metastasis of colorectal cancer [PDF]

, 2018
Caudal type homeobox 2 (CDX2) has been well-established as a diagnostic marker for colorectal cancer (CRC); however, less is known about its regulation, particularly its potential interactions with the DNA repair proteins, adenomatous polyposis coli (APC)
Tiszlavicz László, Herpel Esther, Valicsek Erzsébet, Tóth Csaba, Sükösd Farkas, Schirmacher Peter   +5 more
core   +1 more source

2 shapes the meiotic crossover landscape in relation to interhomolog polymorphism in Arabidopsis [PDF]

, 2020
During meiosis, DNA double-strand breaks undergo interhomolog repair to yield crossovers between homologous chromosomes. To investigate how interhomolog sequence polymorphism affects crossovers, we sequenced multiple recombinant populations of the model ...
Szymanska‐Lejman, Maja, Andrew J Tock, Lambing, C., Ziolkowski, Piotr A, Stuart Desjardins, Bieluszewski, T., Desjardins, Stuart, Desjardins, S., Beth Rowan, Nadia Kbiri, Kbiri, N., Christophe Lambing, Lambing, Christophe, Rowan, Beth, Maja Szymanska‐Lejman, Tock, A., Blackwell, A., Julia Dluzewska, Dluzewska, J., Kbiri, Nadia, Piotr A Ziolkowski, Lawrence, E., Ian R Henderson, Higgins, James D, Alexander R Blackwell, Lawrence, Emma J, James D Higgins, Henderson, I., Henderson, Ian R, Szymanska-Lejman, M., Tock, Andrew J, Emma J Lawrence, Higgins, J., Rowan, B., Blackwell, Alexander R, Bieluszewski, Tomasz, Ziolkowski, P., Tomasz Bieluszewski, Dluzewska, Julia   +38 more
core   +1 more source