Results 81 to 90 of about 5,812 (165)

Mechanisms of resistance to macrophage checkpoint inhibitors in B‐cell non‐Hodgkin lymphoma for the British Journal of Haematology

open access: yes
British Journal of Haematology, EarlyView.
Zachary Hunzeker   +10 more
wiley   +1 more source

circFOXP1 Promotes Pancreatic Ductal Adenocarcinoma Progression Through Regulating EREG/MAPK/ERK Axis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Circular RNAs (circRNAs) are indispensable for triggering pancreatic ductal adenocarcinoma (PDAC) progression. However, the specific biological processes and mechanisms by which circRNAs influence PDAC remain largely unknown. Here, we reported that circFOXP1 is a critical promoter of PDAC progression, exhibiting marked upregulation in patient ...
Leyi Huang   +9 more
wiley   +1 more source

HuCOP1 contributes to the regulation of DNA repair in keratinocytes [PDF]

open access: yes, 2017
We have previously demonstrated that the E3 ligase Human Constitutive Photomorphogenic Protein (huCOP1) is expressed in human keratinocytes and negatively regulates p53.
Németh, István Balázs   +11 more
core   +1 more source

An N‐acetyltransferase‐MAPK fusion protein modulates developmental reprogramming in Physcomitrium patens

open access: yesNew Phytologist, Volume 251, Issue 1, Page 321-339, July 2026.
Summary We discovered a previously uncharacterized moss‐specific protein, Rosetta NATD‐MAPK 1 (RAK1) in Physcomitrium patens, which uniquely integrates MAP kinase (MAPK)‐dependent signaling with N‐acetyltransferase activity. Through phenotypical and biochemical analyses, we characterized RAK1 function in the regulation of the 2D‐to‐3D growth transition.
Cloe de Luxán‐Hernández   +17 more
wiley   +1 more source

Hereditary non-polyposis colorectal carcinoma (HNPCC) : morphological and immunohistochemical studies [PDF]

open access: yes, 2005
Includes bibliographical references.Families with hereditary non-polyposis colorectal carcinoma (HNPCC) are not uncommon along the West-Coast of South Africa.
Holm, Hannes
core  

Hucop1 contributes to the regulation of dna repair in keratinocytes [PDF]

open access: yes, 2016
We have previously demonstrated that the E3 ligase Human Constitutive Photomorphogenic Protein (huCOP1) is expressed in human keratinocytes and negatively regulates p53.
Ádám, É.   +5 more
core   +1 more source

StALKBH10B‐Mediated RNA m6A Modification Inhibits Potato Salt Tolerance by Targeting Flavonoids and ABA Signalling Pathways

open access: yesPlant Biotechnology Journal, Volume 24, Issue 7, Page 4435-4453, July 2026.
ABSTRACT N6‐methyladenosine (m6A) is the most prevalent methylation modification present in mRNAs, which has been confirmed to participate in many developmental and biological processes. However, the biological function and specific regulatory mechanism of m6A modification in relation to salt tolerance of potato remain obscure.
Xuanming Dong   +6 more
wiley   +1 more source

Genotoxic effects of systemic chemotherapy in cancer patients, with special focus on the relation between MSI, LOH and development of secondary cancers [PDF]

open access: yes, 2013
Systemic chemotherapy results in both phenotypic and genotypic side effects. Genotoxicity posed by chemotherapy is a major concern since it induces DNA damage and instability in the patients’ genome. Chemotherapy-related genetic instability is thought to
Rannug, Ulf,   +2 more
core  

Identification of novel genetic and prognostic markers in hereditary and sporadic cancer: "two sides of the same coin" [PDF]

open access: yes, 2012
This thesis has focused on the discovery and characterization of novel diagnostic and prognostic markers in various cancer entities, with a special emphasis on colorectal cancer (CRC).
Piscuoglio, Salvatore
core   +1 more source

Preclinical and Virtual Models of Mucosal Melanoma: Bridging Translational Gaps in a Rare and Lethal Cancer

open access: yesPigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
Integrated physical and virtual modeling provides a scalable framework to overcome sample scarcity, recapitulate mucosal melanoma biology, and accelerate translational discovery toward precision medicine. ABSTRACT Mucosal melanoma (MM) is a rare and lethal subtype of melanoma, disproportionately affecting Asian populations and exhibiting distinct ...
Xiangjie Jin   +4 more
wiley   +1 more source

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