Results 81 to 90 of about 27,093,662 (158)

Receptor for activated C kinase-1 facilitates protein kinase C-dependent phosphorylation and functional modulation of GABA(A) receptors with the activation of G-protein-coupled receptors [PDF]

, 2002
GABA(A) receptors are the principal sites of fast synaptic inhibition in the brain. These receptors are hetero-pentamers that can be assembled from a number of subunit classes: alpha(1-6), beta(1-3), gamma(1-3), delta(1), epsilon, theta, and pi, but the ...
Trevor G Smart, Brandon, NJ, Jovanovic, JN, Moss, SJ, Stephen J Moss, Smart, TG, Nicholas J Brandon, Jasmina N Jovanovic   +7 more
core  

Domain organization and functional analysis of Thermus thermophilus MutS protein

, 1998
MutS protein binds to DNA and specifically recognizes mismatched or small looped out heteroduplex DNA. In order to elucidate its structure–function relationships, the domain structure of Thermus thermophilus MutS protein was studied by performing ...
Hiroyuki Itakura, Koichi Hasegawa, Ryuichi Kato, Keiichi Fukuyama, Hidehisa Tachiki, Ryoji Masui   +5 more
core  

MutS as a tool for mutation detection [PDF]

, 2005
MutS, a DNA mismatch-binding protein, seems to be a promising tool for mutation detection. We present three MutS based approaches to the detection of point mutations: DNA retardation, protection of mismatched DNA against exonuclease digestion, and ...
Sachadyn, Paweł, Stanisławska-Sachadyn, Anna   +1 more
core  

MutS-Homolog2silencing generates tetraploid meiocytes in tomato (Solanum lycopersicum)

, 2017
SUMMARYMSH2 is the core protein of MutS-homolog family involved in recognition and repair of the errors in the DNA. While other members of MutS-homolog family reportedly regulate mitochondrial stability, meiosis, and fertility, MSH2 is believed to ...
Supriya Sarma, Yellamaraju Sreelakshmi, Rameshwar Sharma, Arun Kumar Pandey, Maruthachalam Ravi   +4 more
core   +1 more source

PTCH2 (patched homolog 2 (Drosophila))

, 2008
Review on PTCH2 (patched homolog 2 (Drosophila)), with data on DNA, on the protein encoded, and where the gene is ...
Zaphiropoulos, P
core   +1 more source

Studies on adenine nucleotide states and their role in human MutSα function

, 2012
Mismatch repair is a conserved pathway that corrects errors resulting from the misincorporation of bases during DNA synthesis or from the production of damaged bases. The mismatch repair pathway is initiated by MutS homologs, proteins that recognize and
Asllani, Lored
core   +1 more source

Characterization of murine gammaherpesvirus 68 glycoprotein B (gB) homolog: similarity to Epstein-Barr virus gB (gp110) [PDF]

, 1994
Murine gammaherpesvirus 68 (MHV-68) is a natural pathogen of murid rodents and displays similar pathobiological characteristics to those of the human gammaherpesvirus Epstein-Barr virus (EBV).
Sunil-Chandra, N P, Nash, Anthony, Janjua, N J, Arrand, J R, Stewart, J.P.   +4 more
core  

Conformations of MutS in DNA mismatch repair [PDF]

, 2015
__Abstract__ Prior to cell division, the DNA containing the genetic information of a cell has to be copied. During this process, errors are sometimes incorporated (so-called mismatches), which may cause genetic abnormalities in future cells.
Groothuizen, F.S. (Flora)
core  

Organoids Serve as Viable In Vitro Model for Functional Precision Medicine for Mesonephric-Like Adenocarcinoma of the Ovary. [PDF]

JCO Precis Oncol
Holthaus D, Duc Le H, Matzner L, Kellers F, Rogmans C, Winkler V, Bastian L, Fliedner S, Weimer JP, Busch H, Mandelkow T, Konukiewitz B, Maass N, van Mackelenbergh M, Alkatout I, Bauerschlag DO, Hedemann N.   +16 more
europepmc   +1 more source

Pathological features and prognosis based on microsatellite stability status in colorectal cancer patients: a retrospective analysis. [PDF]

Int J Clin Exp Pathol
Liu X, Yang Y, Zheng H, Zhang Y.
europepmc   +1 more source