Results 91 to 100 of about 5,812 (165)

Mismatch Repair Deficient (dMMR) colorectal carcinoma in a Pakistani cohort: Association with clinical and pathological parameters [PDF]

, 2023
Introduction: Microsatellite instability (MSI) is an important pathway in colorectal carcinoma (CRC) pathogenesis. MSI occurs due to mutations in mismatch repair (MMR) genes that include MutL protein homolog 1 (MLH1), postmeiotic segregation increased 2 (
Faisal, Faiza, Kumar, Ravi, Bukhari, Ummara, Hashmi, Atif A, Sham, Sunder, Irfan, Muhammad, Zia, Shamail, Khan, Abdur Rahim, Rizwan, Ramish, Malik, Umair Arshad   +9 more
core  

Microsatellite instability in colorectal cancer. [PDF]

, 2019
Cilj: Ispitati učestalost mikrosatelitski nestabilnih kolorektalnih karcinoma (CRC) u odnosu na spol, dob i TNM stadij bolesti, u dvogodišnjem razdoblju u Kliničkom bolničkom centru Osijek (KBCO).
Kašuba, Antonija
core  

Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners [PDF]

, 2018
Eukaryotic DNA mismatch repair (MMR) involves both exonuclease 1 (Exo1)-dependent and Exo1-independent pathways. We found that the unstructured C-terminal domain of Saccharomyces cerevisiae Exo1 contains two MutS homolog 2 (Msh2)-interacting peptide ...
William J. Graham, Christine M. Rahal, Bin-Zhong Li, Putnam, Christopher D, Christopher D. Putnam, Richard D. Kolodner, Goellner, Eva M, Graham, William J, Eva M. Goellner, Kolodner, Richard D, Rahal, Christine M, Li, Bin-Zhong   +11 more
core   +1 more source

Multicenter Phase II Trial of Temozolomide in Mycosis Fungoides/Sézary Syndrome: Correlation with O6-Methylguanine-DNA Methyltransferase and Mismatch Repair Proteins [PDF]

, 2011
Purpose: Temozolomide (TMZ) is an oral derivative of dacarbazine that induces DNA damage by methylating nucleotide bases. Resistance has been associated with high levels of O6-methylguanine-DNA methyltransferase (MGMT). Malignant CD4+ T cells of patients
Francine Foss, Alfred Rademaker, M. Eileen Dolan, Joseph Baron, Daniel B. Yarosh, Timothy M. Kuzel, Christiane Querfeld, David S. Pezen, Steven T. Rosen, Joan Guitart   +9 more
core   +1 more source

Lamin A/C as a prognostic biomarker in colorectal cancer [PDF]

, 2007
Lamins A and C (A-type lamins) are type V nuclear intermediate filament proteins which form a complex meshwork underlining the inner nuclear membrane termed the nuclear lamina.
Cox, Thomas Robert
core  

Is there a role for impaired DNA mismatch repair system in the pathogenesis of ameloblastomas? A scoping review. [PDF]

J Oral Biol Craniofac Res
Martins-de-Barros AV, Severino-Lazo RJG, Barreto MEA, Lima GTWF, Costa MJF, Sette-de-Souza PH, Araújo FADC, Barbosa Neto AG.   +7 more
europepmc   +1 more source

Machine Learning-Based Pathomics Signature in Predicting MSH2 Expression and Prognosis in Gastric Cancer. [PDF]

Clin Transl Gastroenterol
Zhang ZR, Wang Y, Yan WW, Li HR, Cheng ZW, Han T, Zhang C, Wang XM.   +7 more
europepmc   +1 more source

Treating microsatellite unstable metastatic parathyroid carcinoma with anti-PD1 therapy. [PDF]

JCEM Case Rep
Amir-Kabirian B, AlRubaye R, Cadle B, Mais D, Sibai Z, Redman R.   +5 more
europepmc   +1 more source

Exceptional Response to Pembrolizumab Immunotherapy in a Young Patient With Lynch Syndrome-Associated Metastatic Colorectal Cancer. [PDF]

Cureus
Niazi M, Crossley R.
europepmc   +1 more source

<i>MSH6</i> gene methylation on clinical pathology and diagnosis in retinoblastoma: a bioinformatics analysis. [PDF]

Int J Ophthalmol
Zhang CF, Zhao L, Jian TM, Guo YF.
europepmc   +1 more source