Results 81 to 90 of about 6,242 (173)

MUTYH Gene [PDF]

, 2020
openaire   +1 more source

OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblasts

Nature Communications
Telomeres are hypersensitive to the formation of the common oxidative lesion 8-oxoguanine (8oxoG), which impacts telomere stability and function. OGG1 and MUTYH glycosylases initiate base excision repair (BER) to remove 8oxoG or prevent mutation.
Mariarosaria De Rosa, Ryan P. Barnes, Ariana C. Detwiler, Prasanth R. Nyalapatla, Peter Wipf, Patricia L. Opresko   +5 more
doaj   +1 more source

Mutation detection in women diagnosed with endometrial cancer: a next-generation sequencing analysis. [PDF]

Mol Cell Oncol
Hussain SS, Amin ZA.
europepmc   +1 more source

Frequent Detection of <i>KRAS</i>-G12C and <i>PIK3CA</i>-Q546K Mutations in MAP Tumors Highlights their Role in <i>MUTYH</i> Variants of Uncertain Significance Reclassification. [PDF]

Hum Mutat
Medeiros ABD, Kozak VN, Picanço-Albuquerque CG, Neto FGKV, Dos Santos GO, Junior SA, Casali-da-Rocha JC, Carraro DM, Torrezan GT.   +8 more
europepmc   +1 more source

Clinicopathological and genotypic characteristics of colorectal cancer patients carrying a germline MUTYH mutation. [PDF]

Rev Assoc Med Bras (1992)
Guzelis I, Gasimli R, Subaşıoğlu A, Sari A.   +3 more
europepmc   +1 more source

[<i>MUTYH-APEX1</i> Axis Promotes Hepatocellular Carcinoma Progression and Therapeutic Resistance by Regulating Cell Cycle Proteins]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Zhou Y, Zhang H, Zhu Y, Jiang P, Feng T, Wu Z, Chen J.   +6 more
europepmc   +1 more source

OGG1 and MUTYH DNA Glycosylases, the Dynamic Duo Against 8-Oxoguanine DNA Lesion: Structure, Regulation, and Novel Emerging Roles. [PDF]

Biomolecules
Gómez-Ramírez AP, Malek M, García-González EG, Campos SE, Brieba LG, David SS, Trasviña-Arenas CH.   +6 more
europepmc   +1 more source

Germline pathogenic variant spectrum and prevalence among colorectal cancer patients undergoing multigene panel testing in Kazakhstan. [PDF]

Sci Rep
Baltayev N, Abdikerim S, Afonin G, Rasulov A, Zhunussova A, Kaidarova D, Zhunussova G.   +6 more
europepmc   +1 more source

MUTYH wt Allele [PDF]

, 2020
openaire   +1 more source

Pathogenic germline variants identified in pNEN patients during genetic testing. [PDF]

Endocr Oncol
Arouchian T, Gangi A, Fung KW, Dumitra T, Levi A, Osipov A, Hendifar AE.   +6 more
europepmc   +1 more source