Results 181 to 190 of about 26,893 (208)

Identification and bioinformatics analysis of genes associated with MVA pathway in Magnolia officinalis

China Journal of Chinese Materia Medica, 2015
Methyl valerate (MVA) pathway is one of the important ways for synthesis of terpenoids. This study was based on data of the transcriptome sequencing of Magnolia officinalis, the associated genes MoACOT, MoHMGS, MoHMGR, MoMK in methyl valerate (MVA) pathway, were completed in detail by using bioinformatics methods.
Liang-ping, Zha, Yuan, Yuan, Lu-qi, Huang, Shu-lin, Yu   +3 more
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Utilisation of the MVA pathway to produce elevated levels of the sesquiterpene α-copaene in potato tubers

Phytochemistry, 2011
Potato flavour is a complex trait resulting from the presence of a combination of volatile and non-volatile compounds. The aim of this work was to investigate the effect of specifically altering the volatile content of tubers and assess its impact on flavour. Tuber-specific over-expression of a potato α-copaene synthase gene resulted in enhanced levels
Wayne L, Morris, Laurence J M, Ducreux, Tom, Shepherd, Efraim, Lewinsohn, Rachel, Davidovich-Rikanati, Yaron, Sitrit, Mark A, Taylor   +6 more
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Molecular cloning and characterization of mevalonic acid (MVA) pathway genes and triterpene accumulation in Panax ginseng

Journal of the Korean Society for Applied Biological Chemistry, 2014
Panax ginseng Meyer is one of the most important medicinal plants in Asia, and ginseng has attracted considerable attention worldwide. Triterpene saponins (ginsenosides) are the main bioactive compounds in P. ginseng. The isoprene units of triterpene are derived from the mevalonic acid (MVA) pathway.
Yong-Kyoung Kim, Yeon Bok Kim, Jae Kwang Kim, Soo-Un Kim, Sang Un Park   +4 more
openaire   +1 more source

[Effects of tHMGR from three different plant sources on mevalonate (MVA) pathway flux in Saccharomyces cerevisiae].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022
In this study, we used bioinformatic tools to analyze the 3-hydroxy-3-methylglutaryl-CoA reductase(HMGR) genes from Glycyrrhiza uralensis, Artemisia annua, and Arabidopsis thaliana. The results indicated that GuHMGR and AaHMGR contained two transmembrane regions while AtHMGR had three transmembrane regions. GuHMGR, AaHMGR, and AtHMGR all had the active
Xiao-Li, Zhang, Er-Kun, Chao, Meng-Chu, Sun, Hong-Fei, Zhao, Cai-Xia, Wang, Bo-Lin, Zhang   +5 more
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The MVA pathway genes expressions and accumulation of celastrol in Tripterygium wilfordii suspension cells in response to methyl jasmonate treatment

Journal of Asian Natural Products Research, 2016
Celastrol is an important bioactive triterpenoid in traditional Chinese medicinal plant, Tripterygium wilfordii. Methyl Jasmonate (MJ) is a common plant hormone which can regulate the secondary metabolism in higher plants. In this study, the mevalonate (MVA) pathway genes in T. wilfordii were firstly cloned. The suspension cells of T.
Yu-Jia, Liu, Yu-Jun, Zhao, Ping, Su, Meng, Zhang, Yu-Ru, Tong, Tian-Yuan, Hu, Lu-Qi, Huang, Wei, Gao   +7 more
openaire   +2 more sources

Past achievements, current status and future perspectives of studies on 3-hydroxy-3-methylglutaryl-CoA synthase (HMGS) in the mevalonate (MVA) pathway

Plant Cell Reports, 2014
HMGS functions in phytosterol biosynthesis, development and stress responses. F-244 could specifically-inhibit HMGS in tobacco BY-2 cells and Brassica seedlings. An update on HMGS from higher plants is presented. 3-Hydroxy-3-methylglutaryl-coenzyme A synthase (HMGS) is the second enzyme in the mevalonate pathway of isoprenoid biosynthesis and catalyzes
Liao, P., Wang, H., Hemmerlin, A., Nagegowda, D.A., Bach, T.J., Wang, M., Chye, M.L.   +6 more
openaire   +5 more sources

Expression pattern of fifteen genes of non-mevalonate (MEP) and mevalonate (MVA) pathways in different tissues of endangered medicinal herb Picrorhiza kurroa with respect to picrosides content

Molecular Biology Reports, 2012
Picrorhiza kurroa, has become an endangered medicinal herb due to excessive utilization, therefore it necessitates the understanding of biology and molecular basis of major chemical constituents i.e. Picroside-I (P-I) and Picroside-II (P-II). Estimation of P-I and P-II in different tissues of P.
Saurabh, Pandit, Kirti, Shitiz, Hemant, Sood, Pradeep Kumar, Naik, Rajinder Singh, Chauhan   +4 more
openaire   +2 more sources

Metabolic engineering of the MVA pathway for isoprenoid production in plants

2017
Invited talk - Session 3: Biotechnology and bioengineering (I) : OL5, p ...
Liao, P, Wang, H, Chen, X, Wang, M, Bach, T J, Chye, ML   +5 more
openaire   +1 more source

Constructing High-Yielding Serratia marcescens for (−)-α-Bisabolol Production Based on the Exogenous Haloarchaeal MVA Pathway and Endogenous Molecular Chaperones

Journal of Agricultural and Food Chemistry
(-)-α-Bisabolol exhibits analgesic, anti-inflammatory, and skin-soothing properties and is widely applied in the cosmetic and pharmaceutical industries. The use of plant essential oil distillation or chemical synthesis to produce (-)-α-bisabolol is both inefficient and unsustainable.
Yao Lu, Di Liu, Long Wang, Yongai Ma, Tai-Ping Fan, Huaxiang Deng, Yujie Cai   +6 more
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[Cloning and analysis of cDNA encoding key enzyme gene (dxr) of the non-MVA pathway in Taxus chinensis cells].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2010
Two distinct routes (classical mevalonate pathway and a novel mevalonate-independent pathway) are utilized by plants for the biosynthesis of isopentenyl diphosphate, the universal precursor of isoprenoids (Fig. 1). Present researches indicated that taxol was synthesized mainly via non-mevalonate pathway, but not genetic evidence was showed.
Qing-Ping, Zheng, Long-Jiang, Yu, Zhi, Liu, Mo-Yi, Li, Fu, Xiang, Qin, Yang   +5 more
openaire   +1 more source