Mevinolin (MEV) modulates terpenoid biosynthesis in 'Shine Muscat' grapes by regulating HMGR enzyme. [PDF]
BMC Plant BiolZheng T +7 more
europepmc +1 more source
Integrated transcriptome and metabolome analysis reveal the sesquiterpenoid biosynthesis mechanism of <i>Atractylodes chinensis</i> under drought stress. [PDF]
Front Plant SciWu Y +6 more
europepmc +1 more source
Therapeutic hepatitis B vaccine employing DNA prime - MVA boost scheme requires additional priming with recombinant HBsAg to elicit an adequate antibody response. [PDF]
Front ImmunolKerth HA +15 more
europepmc +1 more source
Microbial metabolism in deep terrestrial subsurface communities - amino acids as biosignatures. [PDF]
Curr Res Microb SciHerzig M, Bomberg M, Hyötyläinen T.
europepmc +1 more source
Isoprene emission from northern ecosystems under climate change (Ilmastonmuutoksen vaikutukset isopreenipäästöön pohjoisissa ekosysteemeissä) [PDF]
Tiiva, Päivi
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Phosphomevalonate kinase regulates the MVA/MEP pathway in mango during ripening
Plant Physiology and Biochemistry, 2023Mango is a popular tropical fruit with a great diversity in taste and aroma, contributed primarily by terpenoids. Phosphomevalonate kinase (PMK) is a key enzyme for isoprenoid biosynthesis in the mevalonic acid (MVA) pathway responsible for terpenoids.
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Network Analysis of the MVA and MEP Pathways for Isoprenoid Synthesis
Annual Review of Plant Biology, 2013Isoprenoid biosynthesis is essential for all living organisms, and isoprenoids are also of industrial and agricultural interest. All isoprenoids are derived from prenyl diphosphate (prenyl-PP) precursors. Unlike isoprenoid biosynthesis in other living organisms, prenyl-PP, as the precursor of all isoprenoids in plants, is synthesized by two ...
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Bio-isoprene production using exogenous MVA pathway and isoprene synthase in Escherichia coli
Bioresource Technology, 2012In this paper, an original strategy is employed to biosynthesize the isoprene by heterologously co-expressing the Saccharomyces cerevisiae MVA pathway and isoprene synthase (IspS) from Populus alba in the Escherichia coli BL21 (DE3) strain, which was screened from three different IspS enzymes.
Jianming, Yang +6 more
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The multiple plasmid system, mostly relied, for heterogeneous gene expression, results in genetic instability and low mean productivity. To address this, an integration method was employed for investigating expression of heterogenous pathway in E. coli cells; where mevalonate upper pathway was found efficiently expressed.
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Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with high morbidity and mortality. Targeting abnormal cholesterol metabolism is a potential therapeutic direction. Therefore, more natural drugs targeting cholesterol in HCC need to be developed.
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