Results 91 to 100 of about 20,887 (223)

Functional interaction between NCYM and MYCN.

, 2014
(A) Relative mRNA levels of NCYM in SK-N-AS MYCN single copy human neuroblastoma cells transfected with MYCN expression vector. mRNA levels were measured by qRT-PCR with β-actin as an internal control.
Mami Yamamoto (505349), Yusuke Suenaga (505343), Mamoru Kato (4346), Shamim Hossain (505347), Wataru Shoji (505350), Makiko Itami (505351), Tatsuhiro Shibata (281685), S. M. Rafiqul Islam (505344), Seiki Haraguchi (370681), Jennifer Alagu (505345), Akira Nakagawara (32581), Yukichi Tanaka (259254), Atsushi Takatori (505352), Yohko Nakamura (32579), Yoshiki Kaneko (505346), Daisuke Matsumoto (505348), Hidetada Kawana (266333), Miki Ohira (221974)   +17 more
core   +1 more source

Regulation of MYCN expression in human neuroblastoma cells

BMC Cancer, 2009
Background Amplification of the MYCN gene in neuroblastoma (NB) is associated with a poor prognosis. However, MYCN-amplification does not automatically result in higher expression of MYCN in children with NB.
de Vries I, Hulsbergen-van de Kaa Christina A, van Leeuwen Frank N, van Bokhoven Hans, Jacobs Joannes FM, Adema Gosse J, Hoogerbrugge Peter M, de Brouwer Arjan PM   +7 more
doaj   +1 more source

PSEN1 Expression Identifies a Developmentally Distinct Favourable‐Prognosis State in SHH α Medulloblastoma

International Journal of Developmental Neuroscience, Volume 86, Issue 6, October 2026.
High PSEN1 expression identifies a favourable‐prognosis state in SHH α medulloblastoma and is associated with a reproducible transcriptional programme related to cellular homeostasis and development. Its broad expression during cerebellar development and across paediatric brain tumours suggests that its prognostic significance reflects the specific ...
Julia Vanini, Amanda Thomaz, Marina Müller Lupatini, André T. Brunetto, Caroline Brunetto de Farias, Mariane Jaeger, Rafael Roesler   +6 more
wiley   +1 more source

Dangerous liaisons : MYCN meets condensins

, 2014
The condensin complex is required for chromosome condensation during mitosis; however, the role of this complex during interphase is unclear. Neuroblastoma is the most common extracranial solid tumor of childhood, and it is often lethal.
Y. J. Achar, M. Foiani
core   +1 more source

ZIP4 promotes glycolysis in cholangiocarcinoma cells by enhancing H3K4me3 modification and activating MYCN transcription

Zhongguo Linchuang Yixue
ObjectiveTo explore the mechanism by which zinc-regulated transporters, iron-regulated transporter-likeprotein 4 (ZIP4) regulates glycolysis and its impact on tumor progression in cholangiocarcinoma (CCA), providing a theoretical basis for targeted ...
Jiwen WANG, Cheng ZHANG, Dexiang ZHANG, Xiaoling NI, Kun FAN, Houbao LIU   +5 more
doaj   +1 more source

A 67‐year‐old man with a spinal extramedullary mass

Brain Pathology, EarlyView.
Marcella Callea, Francesco Costa, Rosina Paterra, Valeria Barresi   +3 more
wiley   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Correlation Between MYCN Gene Status and MYCN Protein Expression in Neuroblastoma: A Pilot Study To Propose the Use of MYCN Immunohistochemistry in Limited-Resource Areas

Journal of Global Oncology, 2019
PURPOSE: The most significant adverse risk factor for neuroblastoma (NB) is MYCN gene amplification, which strongly associates with high-risk disease.
Teresa Santiago, Nidale Tarek, Fouad Boulos, Caleb Hayes, Sima Jeha, Susana Raimondi, Carlos Rodriguez-Galindo   +6 more
doaj   +1 more source

Long‐Term Outcomes of Patients With Relapsed/Refractory Neuroblastoma Treated on ANBL1221: A Report From the Children's Oncology Group

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol, Arlene Naranjo, Lulu Chen, Rajen Mody, Steven G. DuBois, Rochelle Bagatell, Navin Pinto   +6 more
wiley   +1 more source

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source