Results 91 to 100 of about 10,096 (205)

RE: Comments on cIMPACT‐NOW Update 11

Brain Pathology, EarlyView.
Henning Leske, Richard Doughty, Pitt Niehusmann   +2 more
wiley   +1 more source

Sunitinib suppress neuroblastoma growth through degradation of MYCN and inhibition of angiogenesis.

PLoS ONE, 2014
Neuroblastoma, a tumor of the peripheral sympathetic nervous system, is the most common and deadly extracranial tumor of childhood. The majority of high-risk neuroblastoma exhibit amplification of the MYCN proto-oncogene and increased neoangiogenesis ...
Raul Calero, Esther Morchon, John Inge Johnsen, Rosario Serrano   +3 more
doaj   +1 more source

MYCN Amplification Promotes Enhancer Invasion in Neuroblastoma [PDF]

Cancer Discovery, 2018
Abstract Excess MYCN binds noncanonical enhancers as well as promoters to drive tumor-specific gene expression.
openaire   +1 more source

Neuroblastoma: Anti‐Invasive Effects of Tetracaine In Vitro*

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
Ece Selçuk, David S. Silcock, Amanda Foust, Vicky Bousgouni, Mar Arias‐Garcia, Chris Bakal, Mustafa B. A. Djamgoz, Pinar Uysal‐Onganer   +7 more
wiley   +1 more source

Genetic variation associated with childhood and adult stature and risk of MYCN‐amplified neuroblastoma

Cancer Medicine, 2020
Background Neuroblastoma is the most common pediatric solid tumor. MYCN‐amplification is an important negative prognostic indicator and inherited genetic contributions to risk are incompletely understood.
Eleanor C. Semmes, Erica Shen, Jennifer L. Cohen, Chenan Zhang, Qingyi Wei, Jillian H. Hurst, Kyle M. Walsh   +6 more
doaj   +1 more source

DataSheet1_Identification of a Five-Gene Signature Derived From MYCN Amplification and Establishment of a Nomogram for Predicting the Prognosis of Neuroblastoma.DOCX

, 2021
Yuren Xia (11176598), Xin Li (51274), Xiangdong Tian (1720804), Qiang Zhao (105948)   +3 more
openalex   +2 more sources

Figure S5 from <i>MYCN</i>-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis [PDF]

, 2023
Konstantinos V. Floros, Jinyang Cai, Sheeba Jacob, Richard Kurupi, Carter K. Fairchild, Mayuri Shende, Colin M. Coon, Krista M. Powell, Benjamin R. Belvin, Bin Hu, Madhavi Puchalapalli, Sivapriya Ramamoorthy, Kimberly Swift, Janina P. Lewis, Mikhail G. Dozmorov, John Glod, Jennifer E. Koblinski, Sosipatros A. Boikos, Anthony C. Faber   +18 more
openalex   +1 more source

Supplementary Figure 1 from Venetoclax-based Rational Combinations are Effective in Models of <i>MYCN</i>-amplified Neuroblastoma

, 2023
Krista M. Dalton, Kateryna Krytska, Timothy L. Lochmann, Renata Sano, Colleen Casey, Alessia D'Aulerio, Qasim A. Khan, Giovanna Stein Crowther, Colin M. Coon, Jinyang Cai, Sheeba Jacob, Richard Kurupi, Bin Hu, Mikhail G. Dozmorov, Patricia Greninger, Andrew J. Souers, Cyril H. Benes, Yaël P. Mossé, Anthony C. Faber   +18 more
openalex   +2 more sources

Figure S3 from <i>MYCN</i>-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis

, 2023
Konstantinos V. Floros, Jinyang Cai, Sheeba Jacob, Richard Kurupi, Carter K. Fairchild, Mayuri Shende, Colin M. Coon, Krista M. Powell, Benjamin R. Belvin, Bin Hu, Madhavi Puchalapalli, Sivapriya Ramamoorthy, Kimberly Swift, Janina P. Lewis, Mikhail G. Dozmorov, John Glod, Jennifer E. Koblinski, Sosipatros A. Boikos, Anthony C. Faber   +18 more
openalex   +1 more source

Response of GEM models of neuroblastoma to cabozantinib assessed by multiparametric magnetic resonance imaging

Neoplasia: An International Journal for Oncology Research
Background: In neuroblastoma MYCN amplification is associated with enhanced angiogenesis and poor survival. Mutations in the anaplastic lymphoma kinase (ALK) gene can occur with MYCN amplification, conferring a very poor prognosis.
Gilberto S. Almeida, Philippa King, Albert Hallsworth, Hannah Webber, Sergey Popov, Susana Miranda, Orli Yogev, Andrew D.J. Pearson, Louis Chesler, Yann Jamin, Simon P. Robinson   +10 more
doaj   +1 more source