Results 131 to 140 of about 272,512 (195)

Combining inhibitors of Brd4 and cyclin-dependent kinase can decrease tumor growth in neuroblastoma with MYCN amplification. [PDF]

J Pediatr Surg, 2021
Wood L, Huang M, Zeki J, Gong M, Taylor J, Shimada H, Chiu B.   +6 more
europepmc   +1 more source

Effect of MYCN Amplification on Tumor Response and Recurrence in Patients With Stage IV Neuroblastoma

PURPOSE – MYCN amplification (MYCN-A) is an important prognostic marker in neuroblastoma. However, the impact of MYCN-A in patients with metastasized high-risk neuroblastoma during the course of disease remains unclear.
Researchgr. Nucleaire Geneeskunde, Tytgat, Godelieve A.M., Fiocco, Marta, Matser, Yvette A.H., Langenberg, Karin P.S., Kraal, Kathelijne C.J.M., Genetica, Dierselhuis, Miranda P., van Eijkelenburg, Natasha K.A., Onderzoek Beeld, van Kuilenburg, André B.P., Samim, Atia, van Grotel, Martine, van Noesel, Max M., van Liempt, Lotte M., Molenaar, Jan, Cancer   +16 more
core  

Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma. [PDF]

Front Oncol, 2022
Keller KM, Eleveld TF, Schild L, van den Handel K, van den Boogaard M, Amo-Addae V, Eising S, Ober K, Koopmans B, Looijenga L, Tytgat GAM, Ylstra B, Molenaar JJ, Dolman MEM, van Hooff SR.   +14 more
europepmc   +1 more source

MYCN Amplification Drives Ferroptosis Susceptibility via Cysteine Metabolism in Retinoblastoma. [PDF]

Invest Ophthalmol Vis Sci
Chen Y, Xu H, Xiao L, Zhang Y, Gao Y, Man S, Wang D, Mou K, Huang Y, Yan N, Zhang M.   +10 more
europepmc   +1 more source

¹⁸F-FDG PET/MRI Multiparametric Imaging Features for Predicting MYCN Amplification Status in Children With High-Risk Neuroblastoma. [PDF]

Rev Neurol
Liang J, Li F, Ding Z, Yan B, Zhu Y, Wang F, Xuan W.   +6 more
europepmc   +1 more source

Segmental chromosomal aberrations as the poor prognostic factor in children over 18 months with stage 3 neuroblastoma without MYCN amplification. [PDF]

Front Oncol, 2023
Wieczorek A, Szewczyk K, Klekawka T, Stefanowicz J, Ussowicz M, Drabik G, Pawinska-Wasikowska K, Balwierz W.   +7 more
europepmc   +1 more source

Detection of MYCN Amplification in Neuroblastoma using Competitive PCR Quantitation [PDF]

Laboratory Investigation, 2000
M E, Oude Luttikhuis, V K, Iyer, S, Dyer, P, Ramani, C M, McConville   +4 more
openaire   +2 more sources

GPC2 provides prognostic value in pan-pediatric cancers and is associated with MYCN amplification in neuroblastoma: bioinformatics analysis and validation. [PDF]

BMC Cancer
Xu Y, Zhou Z, Dong Y, Wang G, Zheng L, Lu X, Li S, Zhang M, Gong J, Yang J.   +9 more
europepmc   +1 more source

Case Report: Complete remission in a neonate with high-risk neuroblastoma harboring MYCN amplification and 1p deletion: a case for aggressive early intervention, and literature review. [PDF]

Front Pediatr
Gabitova NK, Cherezova IN, Osipova IV, Sadykova DI, Nasr D, Gobarah AA, Arafat A.   +6 more
europepmc   +1 more source

Effect of <i>MYCN</i> Amplification on Tumor Response and Recurrence in Patients With Stage IV Neuroblastoma. [PDF]

JCO Precis Oncol
Matser YAH, van Kuilenburg ABP, Samim A, van Liempt LM, van Grotel M, Kraal KCJM, Dierselhuis MP, van Eijkelenburg NKA, Langenberg KPS, van Noesel MM, Molenaar J, Fiocco M, Tytgat GAM.   +12 more
europepmc   +1 more source