Results 121 to 130 of about 289,170 (184)

Identification of Crucial Genes Associated With MYCN‐Driven Neuroblastoma Based on Single‐Cell Analysis and Machine Learning

Cancer Medicine
Background Neuroblastoma (NB) with MYCN amplification is strongly correlated with high‐risk stratification and poor prognosis. However, the underlying mechanisms remain incompletely understood.
Jiasi Zhang, Yichen Lei, Yaqin Wang, Wen Yu, Xiaoyan Zhao, Yongbing Zhu, Dedong Zhang, Siying Liu, Aiguo Liu   +8 more
doaj   +1 more source

Combining inhibitors of Brd4 and cyclin-dependent kinase can decrease tumor growth in neuroblastoma with MYCN amplification. [PDF]

J Pediatr Surg, 2021
Wood L, Huang M, Zeki J, Gong M, Taylor J, Shimada H, Chiu B.   +6 more
europepmc   +1 more source

MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors' Efficacy in Neuroblastoma Cells. [PDF]

Int J Mol Sci, 2023
De Rosa P, Severi F, Zadran SK, Russo M, Aloisi S, Rigamonti A, Capranico G, Milazzo G, Perini G.   +8 more
europepmc   +1 more source

Excellent outcome with reduced treatment in infants with nonmetastatic and unresectable neuroblastoma without MYCN amplification: results of the prospective INES 99.1.

, 2011
To evaluate the efficacy of low-dose chemotherapy in infants with nonmetastatic and unresectable neuroblastoma (NB) without MYCN ...
De Bernardi, B., Rubie, H, Canete, A, Gerard, M, Brichard, Bénédicte   +4 more
core  

MYCN Amplification Drives Ferroptosis Susceptibility via Cysteine Metabolism in Retinoblastoma. [PDF]

Invest Ophthalmol Vis Sci
Chen Y, Xu H, Xiao L, Zhang Y, Gao Y, Man S, Wang D, Mou K, Huang Y, Yan N, Zhang M.   +10 more
europepmc   +1 more source

Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma. [PDF]

Front Oncol, 2022
Keller KM, Eleveld TF, Schild L, van den Handel K, van den Boogaard M, Amo-Addae V, Eising S, Ober K, Koopmans B, Looijenga L, Tytgat GAM, Ylstra B, Molenaar JJ, Dolman MEM, van Hooff SR.   +14 more
europepmc   +1 more source

¹⁸F-FDG PET/MRI Multiparametric Imaging Features for Predicting MYCN Amplification Status in Children With High-Risk Neuroblastoma. [PDF]

Rev Neurol
Liang J, Li F, Ding Z, Yan B, Zhu Y, Wang F, Xuan W.   +6 more
europepmc   +1 more source

Segmental chromosomal aberrations as the poor prognostic factor in children over 18 months with stage 3 neuroblastoma without MYCN amplification. [PDF]

Front Oncol, 2023
Wieczorek A, Szewczyk K, Klekawka T, Stefanowicz J, Ussowicz M, Drabik G, Pawinska-Wasikowska K, Balwierz W.   +7 more
europepmc   +1 more source

Detection of MYCN Amplification in Neuroblastoma using Competitive PCR Quantitation [PDF]

Laboratory Investigation, 2000
M E, Oude Luttikhuis, V K, Iyer, S, Dyer, P, Ramani, C M, McConville   +4 more
openaire   +2 more sources

GPC2 provides prognostic value in pan-pediatric cancers and is associated with MYCN amplification in neuroblastoma: bioinformatics analysis and validation. [PDF]

BMC Cancer
Xu Y, Zhou Z, Dong Y, Wang G, Zheng L, Lu X, Li S, Zhang M, Gong J, Yang J.   +9 more
europepmc   +1 more source