Results 131 to 140 of about 125,364 (304)

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru, Nesrine Brahimi, Haleh Zabihi, Cathryn Sibbald, Kyle Seigel, Delaram Shojaei, Eric McMullen, Afsaneh Alavi, Lily Archaempong, Aaron M. Drucker, Adam Weizman, Kenneth Croitoru, Robert Inman, Vincent Piguet   +13 more
wiley   +1 more source

Detection of Mtb and NTM: preclinical validation of a new asymmetric PCR-binary deoxyribozyme sensor assay

Microbiology Spectrum
Tuberculosis (TB) and infectious diseases caused by non-tuberculous mycobacteria (NTM) are global concerns. The development of a rapid and accurate diagnostic method, capable of detecting and identifying different mycobacteria species, is crucial.
Yasmin Castillos das Neves, Ana Julia Reis, Marcos Alaniz Rodrigues, Erica Chimara, Maria Cristina da Silva Lourenço, Jacques Fountain, Ivy Bastos Ramis, Andrea von Groll, Yulia Gerasimova, Kyle H. Rohde, Pedro Eduardo Almeida da Silva   +10 more
doaj   +1 more source

Widespread occurrence of Mycobacterium tuberculosis DNA from 18th-19th century Hungarians [PDF]

, 2003
A large number (265) of burials from 1731-1838 were discovered in sealed crypts of the Dominican Church, Vac, Hungary in 1994. Many bodies were naturally mummified, so that both soft tissues and bones were available.
Donoghue, HD, Fletcher, HA, Holton, J, Pap, I, Spigelman, M   +4 more
core  

Granulomatous Panniculitis in a Patient Treated With Cemiplimab: Case Report and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) have become a cornerstone in the treatment of advanced malignancies by enhancing antitumor immunity, but they may also trigger a broad spectrum of immune‐related adverse events (irAEs) involving multiple organs.
B. Lada‐Colunga, J. L. Artola‐Igarza, N. Martinez‐Peña, I. Arevalo‐Ortega, J. Rodriguez‐Blandon, G. Cancho‐Galan, R. Izu‐Belloso   +6 more
wiley   +1 more source

Long-term feeder cell-free cat intestinal organoid cultures to study Toxoplasma gondii’s sexual development

Communications Biology
Toxoplasma gondii is a protozoan parasite able to infect and survive in diverse host environments. However, its sexual reproduction, culminating in infectious oocysts, occurs exclusively in feline intestines.
David Warschkau, Tobias Hoffmann, Michael Laue, Antonia Müller, Chandra Ramakrishnan, Giulia Rigamonti, Fabrizia Veronesi, Elvio Lepri, Mohamed Ali Hakimi, Christian Klotz, Frank Seeber   +10 more
doaj   +1 more source

Dermatologic Best Practices for Manicures and Nail Care: A Systematic Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Manicure and pedicure procedures are widely viewed as benign cosmetic practices, yet emerging evidence links them to various dermatologic complications, including dermatitis, infection, photodamage and, in rare cases, cutaneous malignancy.
Nivetha Aravind, Olivia Burke, Brian W. Morrison   +2 more
wiley   +1 more source

What Immunological Defects Predispose to Non-tuberculosis Mycobacterial Infections? [PDF]

, 2017
Nontuberculous mycobacteria (NTM) are categorized as one of the large and diverse groups of environmental organisms which are abundant in water and soil.  NTM cause a variety of diseases in humans that mainly affect the lung.
Adcock, IM, Garssen, J, Kazempour Dizagie, M, Mirsaeidi, M, Moloudizargari, M, Mortaz, E, Movassaghi, M, Varahram, M   +7 more
core  

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source