Results 111 to 120 of about 94,343 (260)

Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis.

, 2006
CD8 T lymphocytes are important effectors in protective immunity against Mycobacterium tuberculosis. We recently characterized the detour pathway of CD8 T cell activation in tuberculosis mediated by apoptotic vesicles from infected cells that transport ...
Hoops, Silvia Locatelli, Subash Sad, Sandhoff, Konrad, de Diego, Juana, Konrad Sandhoff, Bernadette Breiden, Juana de Diego, Winau, Florian, Weber, Stephan, Sad, Subash, Silvia Locatelli Hoops, Kaufmann, Stefan HE, Ulrich E. Schaible, Volker Brinkmann, Florian Winau, Breiden, Bernadette, Brinkmann, Volker, Schaible, Ulrich E, Stephan Weber, Stefan H.E. Kaufmann   +19 more
core   +1 more source

Extraintestinal Manifestation of Crohn's Disease in the Middle Ear—A Case Report

The Laryngoscope, EarlyView.
A unique clinical case with extraintestinal manifestation of Crohn's disease in the middle ear, causing severe inflammation and troublesome symptoms. The combination of systemic therapy and surgery curbed the middle ear manifestation upon diagnosis.
Julia Arebro
wiley   +1 more source

Dynamics of Mpox infection in Nigeria: a systematic review and meta-analysis

Scientific Reports
The seasonal outbreaks of Mpox continue in most parts of West and Central Africa. In the past year, Nigeria had the highest number of reported cases.
Simeon Cadmus, Victor Akinseye, Matthias Besong, Tobi Olanipekun, John Fadele, Eniola Cadmus, Rashid Ansumana, Daniel Oluwayelu, Solomon O. Odemuyiwa, Oyewale Tomori   +9 more
doaj   +1 more source

When more sugar is better—a GPI side chain modification results in a less virulent phenotype during a protozoan infection

mBio
The assembly and function of side chain modifications of glycosylphosphatidylinositol (GPI) units (anchors or free forms) are poorly defined. In a recent study, two enzymes, PIGJ and PIGE, of the protozoan parasite Toxoplasma gondii were identified and ...
Frank Seeber
doaj   +1 more source

Electroporation of mycobacteria.

, 2015
International audienceHigh-efficiency transformation of DNA is integral to the study of mycobacteria, allowing genetic manipulation. Electroporation is the most widely used method for introducing DNA into mycobacterial strains. Many parameters contribute
Parish, Tanya, David M. Roberts, Tanya Parish, Goude, Renan, Roberts, David M, Renan Goude   +5 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Pyrazinoic acid, the active form of the anti-tuberculosis drug pyrazinamide, and aromatic carboxylic acid analogs are protonophores

Frontiers in Molecular Biosciences
Pyrazinoic acid is the active form of pyrazinamide, a first-line antibiotic used to treat Mycobacterium tuberculosis infections. However, the mechanism of action of pyrazinoic acid remains a subject of debate, and alternatives to pyrazinamide in cases of
Fabio L. Fontes, Fabio L. Fontes, Steven A. Rooker, Jamie K. Lynn-Barbe, Michael A. Lyons, Debbie C. Crans, Debbie C. Crans, Dean C. Crick, Dean C. Crick   +8 more
doaj   +1 more source

Studies on chromogenic mycobacteria.

, 1965
The term "chromogenic mycobacteria" is but one of several commonly used to describe acid-fast bacilli which differ from M. tuberculosis, and which for the past ten years have been isolated from clinical specimens with steadily increasing frequency ...
Butler, Ralph W.
core  

Mycobacteria in Nail Salon Whirlpool Footbaths, California

, 2005
In 2000, an outbreak of Mycobacterium fortuitum furunculosis affected customers using whirlpool footbaths at a nail salon. We swabbed 30 footbaths in 18 nail salons from 5 California counties and found mycobacteria in 29 (97%); M.
Edward Desmond, Yvonne Jang, Janet Ely, Candi Zizek, Kevin L. Winthrop, Duc J. Vugia   +5 more
core   +1 more source