Results 101 to 110 of about 94,343 (260)

Organ‐Resolved Host Proteomic and Post‐Translational Modification Landscapes in a Mouse Model of Talaromyces marneffei Infection

iMetaMed, EarlyView.
We presented an organ‐resolved, multiple PTM remodeling atlas of systemic T. marneffei infection, integrating quantitative proteome, phosphoproteome, ubiquitinome, acetylome, and lactylome data across the liver, lung, and spleen. The atlas delineated organ‐specific PTM signatures and a functional convergence of divergent modification types on immune ...
Wudi Wei, Shiyi Lai, Xiaotao He, Xiaoting Wei, Xiaoting Xie, Weihong Huang, Baili Zhan, Meng Zhang, Zongxiang Yuan, Rongfeng Chen, Jingzhen Lai, Yuyuan Huang, Kang Li, Sanqi An, Li Ye, Hao Liang, Junjun Jiang   +16 more
wiley   +1 more source

Characteristics of nontuberculous mycobacteria from a municipal water distribution system and their relevance to human infections [PDF]

, 2013
This thesis documented pathogenic species of nontuberculous mycobacteria in the Brisbane water distribution system. When water and shower aerosol strains were compared with human strains of mycobacteria, the study found that the likelihood of acquiring ...
Thomson, Rachel M
core  

Rapidly growing mycobacteria and skin infection

, 2017
Rapidly growing mycobacteria (RGM) are among the most common nontuberculous mycobacteria (NTM) associated with cutaneous infections in industrialized ...
Domenico Bonamonte, Bonamonte D., Verni P., Gianni Angelini, Filoni A., Angela Filoni, Pietro Verni, Angelini G.   +7 more
core   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source

Comparative Diagnostic Performance of Three Commercial Real‐Time PCR Assays for the Detection of Mycobacterium tuberculosis Complex in Bronchial Washing Specimens: A Large Retrospective Study

Journal of Clinical Laboratory Analysis, EarlyView.
This large retrospective study compared the diagnostic performance of three commercial real‐time PCR assays (AdvanSure TB/NTM, Cobas MTB, and Xpert MTB/RIF) for MTBC detection in 3348 bronchial washing specimens. In a head‐to‐head comparison of 740 specimens, the Cobas MTB and Xpert MTB/RIF assays showed markedly higher sensitivity than the AdvanSure ...
Jimyung Kim, Yumi Park
wiley   +1 more source

Cholesterol is accumulated by mycobacteria but its degradation is limited to non-pathogenic fast-growing mycobacteria

, 2000
In this report we show that fast-growing non-pathogenic mycobacteria degrade cholesterol from liquid media, and are able to grow on cholesterol as a sole carbon source.
Rafat Sobouti, Yossef Av-Gay
core   +1 more source

Beyond the gut: Non‐specific interstitial pneumonia in pediatric ulcerative colitis—A rare extra‐intestinal manifestation

JPGN Reports, EarlyView.
Abstract Inflammatory bowel disease (IBD) is a chronic inflammatory disorder often presenting with extra‐intestinal manifestations (EIMs) involving the skin, joints and eyes. However, pulmonary manifestation, such as interstitial lung disease (ILD), is a rare complication, particularly in the pediatric population. We report a case of a 10‐year‐old boy,
Harshit Vachher, Vishrutha Poojari, Shivangi Tetarbe, Parmarth Chandane, Lakshmi Shobhavat, Ira Shah   +5 more
wiley   +1 more source

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak, Reinhard Dummer, Egle Ramelyte   +2 more
wiley   +1 more source

A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

eLife
The Nix-TB clinical trial evaluated a new 6 month regimen containing three oral drugs; bedaquiline (B), pretomanid (Pa), and linezolid (L) (BPaL regimen) for the treatment of tuberculosis (TB).
Malik Zohaib Ali, Taru S Dutt, Amy MacNeill, Amanda Walz, Camron Pearce, Ha Lam, Jamie S Philp, Johnathan Patterson, Marcela Henao-Tamayo, Richard Lee, Jiuyu Liu, Gregory T Robertson, Anthony J Hickey, Bernd Meibohm, Mercedes Gonzalez Juarrero   +14 more
doaj   +1 more source

Using MycDB on the World-Wide Web

MycDB is an integrated mycobacterial database. This means that it contains information on all aspects of mycobacteria, whether immunology, metabolism, or the researchers working on mycobacteria.
Bergh, S, Cole, S T, Stewart T. Cole, Staffan Bergh   +3 more
core   +1 more source