Results 101 to 110 of about 125,364 (304)

Widespread macrolide resistance among rapidly growing mycobacteria due to plasmids containing erm(55)

Scientific Reports
Macrolides (clarithromycin and azithromycin) are a mainstay of therapy for infections caused by rapidly growing mycobacteria (RGM). Historically, macrolide resistance in RGM species is associated with mutations in the 23S rRNA gene and chromosomal ...
Christopher I. Graham, Barbara A. Brown-Elliott, Bibiana Gonzalez-Ramirez, Kavya Somayaji, Stephanie Melton, Michelle Wuzinski, Nancy L. Wengenack, Richard J. Wallace, David C. Alexander   +8 more
doaj   +1 more source

Optimization of rTDMH as a Reagent Toward Improving the Sensitivity of the RT-PCR Based Diagnosis for Mycobacterium Tuberculosis [PDF]

, 2012
Current diagnostic tools being used for tuberculosis lack the speed and sensitivity necessary to successfully combat the current tuberculosis epidemic.
Bhatti, Alexandra
core  

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Biology of clinical mycobacteria strains

Біологічні студії, 2009
Mycobacteria are very varied microorganisms. This peculiarity make great trouble among ftysiatres, because quantity of patients increases and clinical essence of diseases, which caused by mycobacteria, often are not understand.
H. Yavorska, R. Sybirna
doaj   +1 more source

From Cell‐Free Transcriptomes to Single‐Cell Landscapes: Biomarker Discovery and Originating Cell Alteration Analysis via Graph Matrix Factorization

Advanced Science, EarlyView.
CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang, Wenjing Zhang, Hang Wei, Shiyan Liu, Junliang Shang, Weijie Gong, Hanwen Cheng, Xiujuan Lei, Yuhui Kou, Baoguo Jiang   +9 more
wiley   +1 more source

Sputum microscopy for the diagnosis of HIV-associated pulmonary tuberculosis in Tanzania. [PDF]

, 2008
\ud In many resource poor settings only sputum microscopy is employed for the diagnosis of HIV-associated pulmonary tuberculosis; sputum culture may not be available.
Bakari, Muhammad, Lounasvaara, Tarja, Lyimo, Johnson, Matee, Mecky, Mtei, Lillian, Pallangyo, Kisali, von Reyn, C Fordham, Waddell, Richard, Wieland-Alter, Wendy   +8 more
core   +3 more sources

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, EarlyView.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Evaluating the efficacy of HRZE-based regimens in a high-burden murine model: a back-translational assessment of rifamycins and moxifloxacin substitutions in tuberculosis treatment

Frontiers in Pharmacology
IntroductionThe standard treatment for tuberculosis is the isoniazid, rifampicin, pyrazinamide, and ethambutol (HRZE) regimen. Despite its efficacy, this regimen has limitations, including prolonged treatment duration and poor clinical outcomes in drug ...
Jason E. Cummings, Lisa K. Woolhiser, Vincent Guglielmi, Machenzie Wernsman, Ashley Romano, Samantha Pauly, Samantha Pauly, John T. Belisle, Nicholas D. Walter, Nicholas D. Walter, Nicholas D. Walter, Gregory T. Robertson, Gregory T. Robertson, Richard A. Slayden   +13 more
doaj   +1 more source

Mycobacteria in water [PDF]

Journal of Applied Bacteriology, 1984
C H, Collins, J M, Grange, M D, Yates
openaire   +2 more sources

Of Microsoft and Mycobacteria [PDF]

Canadian Journal of Infectious Diseases and Medical Microbiology, 2001
Bill Gates should have run for President of the United States. Not only would he have been a candidate with some legitimate claim to the Internet, but his call for a major increase in funding for new defence systems would have been supported by the general public, both at home and abroad.
openaire   +3 more sources