Results 81 to 90 of about 125,364 (304)

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

Advanced Materials Interfaces, EarlyView.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido, Aída Jimena Velarde‐Salcedo, Alejandro López‐Amador, Noé Arjona, Citlali Uitz Toalá, Carmen Gonzalez, Beatriz Liliana España‐Sánchez   +6 more
wiley   +1 more source

The DosR regulon of Mycobacterium avium and adaptation to hypoxia

Frontiers in Cellular and Infection Microbiology
Like other tuberculous and nontuberculous mycobacterial pathogens of human lung such as Mycobacterium tuberculosis and M. abscessus, M. avium is likely exposed to a variety of stressors during infection, including hypoxic conditions inside activated ...
Juan M. Belardinelli, Charlotte Avanzi, Kelsey E. Martin, Kelsey E. Martin, Ha Lam, Marte S. Dragset, Marte S. Dragset, William H. Wheat, Brendan K. Podell, Mercedes Gonzalez-Juarrero, Mercedes Gonzalez-Juarrero, Mary Jackson, Mary Jackson   +12 more
doaj   +1 more source

Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]

, 2016
Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
AT Cruz, CA Wright, CA Wright, CA Wright, CC Anunobi, CC Boehme, CJL Murray, CM Denkinger, CM Denkinger, CM Perez-Velez, D Hillemann, E Penz, Edward Masika, ES Cibas, F Ardito, FA Mhimbira, Hans-Peter Beck, Hassan Chande, J Ayugi, J Cohen, JA Seddon, JB Reitsma, Klaus Reither, L Coetzee, Levan Jugheli, M Pai, Maira Bholla, Mohamed Sasamalo, Neema Kapalata, PJ Dodd, R Fang, RR Kazwala, S Chakravorty, SGM Mfinanga, SH Siddiqi, SM Newton, Tracy R. Glass, Ustar Biotechnologies, World Health Organization, X Ou   +39 more
core   +3 more sources

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin   +117 more
core   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

KCNJ2 is Required for NLRP3 Inflammasome Activation That Drives Allergic Airway Inflammation and Remodeling

Advanced Science, EarlyView.
This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui, Shumei Wu, Yang Peng, Yiqi Liu, Li Che, Shiying Chen, Feng Zhang, Dajiang Qin, Shiyue Li, Pixin Ran, Wenguang Yin   +10 more
wiley   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie, EarlyView.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +2 more sources

Cell envelope polysaccharide modifications alter the surface properties and interactions of Mycobacterium abscessus with innate immune cells in a morphotype-dependent manner

mBio
Mycobacterium abscessus is one of the leading causes of pulmonary infections caused by non-tuberculous mycobacteria. The ability of M. abscessus to establish a chronic infection in the lung relies on a series of adaptive mutations impacting, in part ...
Elena Lian, Juan M. Belardinelli, Kavita De, Arun Prasad Pandurangan, Shiva K. Angala, Zuzana Palčeková, Anna E. Grzegorzewicz, Josephine M. Bryant, Tom L. Blundell, Julian Parkhill, R. Andres Floto, William H. Wheat, Mary Jackson   +12 more
doaj   +1 more source

Mycobacteria and allergies

Immunobiology, 2007
Exposure to mycobacteria was inevitable throughout mammalian evolution. Most mycobacteria are saprophytic environmental organisms that are enormously abundant in soil and untreated water and evoke immune responses in the residents of developing countries. A few species are pathogens.
Graham A W, Rook, Eckard, Hamelmann, L Rosa, Brunet   +2 more
openaire   +2 more sources