Results 81 to 90 of about 94,343 (260)

Giardia's Epithelial Cell Interaction In Vitro: Mimicking Asymptomatic Infection?

Frontiers in Cellular and Infection Microbiology, 2017
The protozoan parasite Giardia duodenalis is responsible for more than 280 million cases of gastrointestinal complaints (“giardiasis”) every year, worldwide. Infections are acquired orally, mostly via uptake of cysts in contaminated drinking water. After
Martin R. Kraft, Martin R. Kraft, Christian Klotz, Roland Bücker, Jörg-Dieter Schulzke, Toni Aebischer   +5 more
doaj   +1 more source

Mycobacterial lysocardiolipin is exported from phagosomes upon cleavage of cardiolipin by a macrophage-derived lysosomal phospholipase A2. [PDF]

, 2001
Pathogenic mycobacteria are able to survive and proliferate in phagosomes within host macrophages (Mphi). This capability has been attributed in part to their cell wall, which consists of various unique lipids.
Torrelles, J., Schaible, UE, Fischer, K, Chatterjee, D., Chatterjee, D, Fischer, K., Brennan, PJ, Schaible, U., Brennan, P., Torrelles, J, Kaufmann, S., Kaufmann, SH   +11 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

The diversity and distribution of Mycobacterium species in varying ecological and climatic environments [PDF]

The species within the genus Mycobacterium are commonly detected in a variety of environments including soil, water and dust. Many species within the group are capable of causing opportunistic diseases and are hypothesised to be responsible for the ...
Khera, Tanya
core  

Mechanism of Isonitrilase, a Nonheme Iron Decarboxylase Involved in the Biosynthesis of the Isonitrile Group in Peptides: A Computational Study

Chemistry – A European Journal, EarlyView.
A combination of molecular dynamics and quantum mechanics calculations shows that substrate is tightly bound inside the enzyme structure that enables two successive catalytic cycles with dioxygen and α‐ketoglutarate with an initial desaturation followed by hydrogen abstraction and decarboxylation steps to form an isonitrile substituent.
Chengxu Zhu, Sam P. de Visser
wiley   +1 more source

Repurposing—a ray of hope in tackling extensively drug resistance in tuberculosis

International Journal of Infectious Diseases, 2015
Tuberculosis (TB) remains a serious concern more than two decades on from when the World Health Organization declared it a global health emergency. The alarming rise of antibiotic resistance in Mycobacterium tuberculosis, the etiological agent of TB, has
Arundhati Maitra, Sadé Bates, Trupti Kolvekar, Padma V. Devarajan, Juan D. Guzman, Sanjib Bhakta   +5 more
doaj   +1 more source

Occurrence of pathogenic environmental mycobacteria on surfaces in health institutions

, 2010
Maria Gorete Mendes dé souza1, Daisy Nakamura Sato2, Clarice Queico Fujimura Leite3, Sérgio Roberto de Andrade Leite4, Flávio Garcia Sartori1, Karina de Andrade Prince3, Luciana Assirati Casmeiro1, Carlos Henrique Gomes ...
Daisy Nakamura Sato, Clarice Queico Fujimura Leite, et al, Maria Gorete Mendes dé Souza   +3 more
core  

Thiamine Diphosphate‐Dependent Biocatalysis in the 21st Century

Chemistry – A European Journal, EarlyView.
This account summarizes the major discoveries and recent advances, highlighting the biocatalytic abilities, mechanistic studies, and feature‐based classification that are shaping emerging perspectives on thiamine diphosphate (ThDP)‐dependent catalysis.
Lucrezia Lanza, Daniela Bjarnesen, Michael Müller   +2 more
wiley   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source