Results 201 to 210 of about 78,834 (283)

A Subset of Circulating Blood Mycobacteria-Specific CD4 T Cells Can Predict the Time to Mycobacterium tuberculosis Sputum Culture Conversion

, 2014
Catherine Riou, Clive M. Gray, Masixole Y. Lugongolo, Thabisile Gwala, Agano Kiravu, Pamela Deniso, Lynsey Stewart‐Isherwood, Shaheed Vally Omar, Martin P. Grobusch, Gerrit Coetzee, Francesca Conradie, Nazir Ismail, Gilla Kaplan, Dorothy Fallows   +13 more
openalex   +2 more sources

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Clinical course and outcomes of patients with anti-interferon-gamma autoantibody-associated adult-onset immunodeficiency: an observational cohort study. [PDF]

Ann Med
Angkasekwinai N, Wongsawat E, Vorasan N.
europepmc   +1 more source

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells

Immunology, EarlyView.
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si, Gaochen Zhu, Qianling Jiang, Xin Ma, Guan Yang   +4 more
wiley   +1 more source

Non-tuberculous mycobacterial infection in cystic fibrosis before and after initiation of elexacaftor/tezacaftor/ivacaftor: now is not the time to lower the guard. [PDF]

BMJ Open Respir Res
Evans IES, Smith D, Henderson D, Riddles T, Masel P, Moore V, Burke AJ, Thomson RM, Reid DW.   +8 more
europepmc   +1 more source

CULTURE-BASED MICROFLUIDIC DEVICE FOR RAPID DETECTION OF MYCOBACTERIA

, 2004
Gaoshan Jing
openalex   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

Immunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima, Ricardo C. Castro, Francisco R. Javier, Caroline Fontanari, Valdes R. Bollela, Rogerio S. Rosada, Célio L. Silva, Lúcia H. Faccioli, Luiz G. Gardinassi, Fabiani G. Frantz   +9 more
wiley   +1 more source

Promising Approaches Based on Bioimaging Reporters for Direct Rapid Detection of <i>Mycobacterium tuberculosis</i>. [PDF]

Biomedicines
Ambartsumyan OA, Skuredina OA, Eliseev PI, Tiulkova TE, Samoilova AG, Vasilieva IA.   +5 more
europepmc   +1 more source

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

Immunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng, Eimear K. Ryan, Michael Bennett, Christy Clutter, Jackson G. Cacioppo, Jeffrey Aubé, Andy E. Hogan, Daniel T. Leung   +7 more
wiley   +1 more source

Distribution, prevalence of non-tuberculous mycobacteria on Hainan Island and antibiotic resistance of <i>Mycobacterium abscessus</i>. [PDF]

Microbiol Spectr
Xu X, Huang J, Wang H, Xiang T, Liu J, Zheng L.   +5 more
europepmc   +1 more source