This large‐scale study of over one‐million musculoskeletal swabs highlights anatomical variability in microbial contamination of musculoskeletal tissues and identifies high‐risk recovery zones for virulent organisms. ABSTRACT Background Microbial contamination of musculoskeletal tissues recovered from deceased donors poses a risk for donor‐derived ...
Anthony Montedonico +3 more
wiley +1 more source
Antimycobacterial Peptides: From Natural Product Discovery to AI Guided Design. [PDF]
Biswas D, Medina SH.
europepmc +1 more source
Recipient–Donor Sex Combinations and Posttransplant Infections: A Swiss Transplant Cohort Study
In this cohort study of 5033 patients, only the recipient sex, in particularly kidney recipients, was independently associated with an increased risk of infections, when compared to males. These findings indicate that recipient–donor sex combination does not influence short‐term solid organ transplantation outcome.
Christian T. J. Magyar +16 more
wiley +1 more source
Naturally occurring dinactin targets cpsA protein and kills Mycobacterium tuberculosis by disrupting the proton motive force. [PDF]
Wang G +12 more
europepmc +1 more source
ABSTRACT Background Tuberculous pleural effusion (TPE), the second most common form of extra‐pulmonary tuberculosis (TB), remains difficult to diagnose due to low‐yield, invasive and often unavailable diagnostics in resource‐limited settings. This study aimed to evaluate the diagnostic accuracy of sonographic characteristics alone to predict TB ...
Lukonde Zimba +3 more
wiley +1 more source
Seven decades of nontuberculous mycobacteria in Denmark: shifts in species distribution and clinical relevance. [PDF]
Iversen XES +8 more
europepmc +1 more source
Assessment of Antimicrobial Resistance in M. leprae Strains From Kiribati
ABSTRACT Objectives Kiribati has one of the highest rates of leprosy worldwide. A nationwide screening and chemoprophylaxis program for household leprosy contacts was introduced in 2018. In 2022, population‐wide screening and rifamycin‐based treatment or chemoprophylaxis for leprosy and tuberculosis was introduced as part of the PEARL and COMBINE ...
Patrick O. Campbell +10 more
wiley +1 more source
Phenotypic and transcriptomic characterization of two newly described Mycobacterium species within the <i>Mycobacterium gordonae</i> complex. [PDF]
Gan T +5 more
europepmc +1 more source
Altered Pharmacokinetics and Delayed Sputum Conversion in Tuberculosis Patients Co‐Infected With HIV
ABSTRACT Background HIV co‐infection affects host responses and pharmacokinetics (PK) of tuberculosis (TB) treatment. This study assessed the PK of first‐line anti‐TB drugs and clinical outcomes in patients with and without HIV co‐infection. Methods In this prospective observational study, 61 adults with sputum‐positive pulmonary TB, either confirmed ...
Aung Pyae Phyo +14 more
wiley +1 more source
FtsK with a unique N-terminal extension is involved in coordinating the final steps of chromosome segregation with asymmetric division in mycobacterial cells. [PDF]
Milcarz K +6 more
europepmc +1 more source

