Results 171 to 180 of about 94,343 (260)

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines

open access: yesImmunology, EarlyView.
This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw   +10 more
wiley   +1 more source

Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA. [PDF]

open access: yesElife
Bi Z   +9 more
europepmc   +1 more source

Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley   +1 more source

Pejerrey (Odontesthes bonariensis) Under Siege: Main Infectious Diseases and Their Role in Aquaculture and Wild Populations Amidst Environmental Change

open access: yesJournal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT The pejerrey (Odontesthes bonariensis) is a key species for recreational and commercial fisheries in Argentina and holds significant aquaculture potential. It has been introduced to various countries worldwide, including Japan, where intensive aquaculture has developed.
Aarón Torres‐Martínez   +4 more
wiley   +1 more source

Temperature and pH growth preferences predict the pathogenicity and environmental distributions of nontuberculous mycobacteria. [PDF]

open access: yesmSystems
Gebert MJ   +7 more
europepmc   +1 more source

Isolation and Identification of Erysipelothrix sp. in Hybrid Grouper (Epinephelus fuscoguttatus × E. lanceolatus) in Taiwan

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT In February 2025, a mortality event of unknown aetiology occurred at a hybrid grouper (Epinephelus fuscoguttatus × Epinephelus lanceolatus) aquaculture farm in southern Taiwan, with sporadic daily deaths persisting for a month. Four moribund groupers were collected over three sampling intervals for diagnostic investigation.
Shang‐Ting Wu   +2 more
wiley   +1 more source

Structure‐Based Annotation by AlphaFold3 Predictions of the Francisella halioticida T6SS Encoded in the Francisella Pathogenicity Island

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Francisella halioticida has emerged as a significant pathogen of cultured molluscs, causing substantial economic losses due to mass mortalities. The Francisella Pathogenicity Island encodes a Type VI secretion system essential for virulence and intracellular persistence. However, the F.
Hélène Bouras   +2 more
wiley   +1 more source

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