Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min +2 more
wiley +1 more source
Soil microbial diversity: The hidden wealth of sustainable farming
Abstract Soil harbors diverse microbial communities that are fundamental to soil health and agricultural sustainability. Despite their ecological and agronomic importance, these communities remain underutilized as biological resources for improving crop production.
Mohan Singh Rana +6 more
wiley +1 more source
Astrocytic EAAT‐2 Upregulation Supports Neuro‐Axonal Homeostasis in Chronic Inflammatory CNS Lesions
Inflammatory CNS lesions increase extracellular glutamate. Astrocytic EAAT regulation controls glutamate clearance, stabilizes axonal Ca2+ homeostasis, and determines neurite survival during chronic neuroinflammation. ABSTRACT Neuronal loss in multiple sclerosis (MS) is a key factor in the progression of disability.
Luise Reukauf +9 more
wiley +1 more source
Dual-modal LAMP platform integrating biosensor and real-time fluorescence for rapid differentiation of <i>Mycobacterium tuberculosis</i> complex from nontuberculous mycobacteria. [PDF]
Huang J +11 more
europepmc +1 more source
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil +7 more
wiley +1 more source
Comparison of diagnostic accuracy and sensitivity of Kinyoun and auramine-rhodamine stains in detecting mycobacteria from specimen smears. [PDF]
Mahmud HA, She RC.
europepmc +1 more source
Mānuka Honey and Leaf Bioactives: A Review of Taonga Natural Products From Leptospermum scoparium
This comprehensive review of mānuka examines its cultural significance, botany, distinct genetics and unique phytochemistry. It highlights mānuka honey, enriched with antibacterial methylglyoxal derived from nectar dihydroxyacetone, and details markers used to combat honey fraud.
John W. van Klink +2 more
wiley +1 more source
New concepts of chitosan-based mucosal formulations for supporting control of the gastric pathogen <i>Helicobacter pylori</i>. [PDF]
Jaroniek P +3 more
europepmc +1 more source
ABSTRACT Clinically used analgesics such as gabapentinoids and opioids have limited efficacy and adverse effects like abuse liability, and there is a dire need for novel analgesics with improved safety profiles. Since lysophosphatidic acid can induce neuropathic pain in rodents, LPA receptor antagonists have been investigated as potential analgesics ...
Kristen L. Woodhouse +6 more
wiley +1 more source
Pulmonary infection by non-tuberculous mycobacteria in an endemic region for tuberculosis in Northeast Brazil. [PDF]
Lima AS +6 more
europepmc +1 more source

