Results 211 to 220 of about 94,343 (260)

Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min   +2 more
wiley   +1 more source

Soil microbial diversity: The hidden wealth of sustainable farming

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 4, December 2026.
Abstract Soil harbors diverse microbial communities that are fundamental to soil health and agricultural sustainability. Despite their ecological and agronomic importance, these communities remain underutilized as biological resources for improving crop production.
Mohan Singh Rana   +6 more
wiley   +1 more source

Astrocytic EAAT‐2 Upregulation Supports Neuro‐Axonal Homeostasis in Chronic Inflammatory CNS Lesions

open access: yesGlia, Volume 74, Issue 12, December 2026.
Inflammatory CNS lesions increase extracellular glutamate. Astrocytic EAAT regulation controls glutamate clearance, stabilizes axonal Ca2+ homeostasis, and determines neurite survival during chronic neuroinflammation. ABSTRACT Neuronal loss in multiple sclerosis (MS) is a key factor in the progression of disability.
Luise Reukauf   +9 more
wiley   +1 more source

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli : Tuning inclusion body architecture and protein yield via dissolved oxygen control

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 12, Page 2550-2562, December 2026.
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil   +7 more
wiley   +1 more source

Mānuka Honey and Leaf Bioactives: A Review of Taonga Natural Products From Leptospermum scoparium

open access: yesNew Zealand Journal of Botany, Volume 64, Issue 4, December 2026.
This comprehensive review of mānuka examines its cultural significance, botany, distinct genetics and unique phytochemistry. It highlights mānuka honey, enriched with antibacterial methylglyoxal derived from nectar dihydroxyacetone, and details markers used to combat honey fraud.
John W. van Klink   +2 more
wiley   +1 more source

Characterization of the Lysophosphatidic Acid Receptor 5 Antagonist RLPA‐76 as a Novel Analgesic in Male Rats and Mice

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Clinically used analgesics such as gabapentinoids and opioids have limited efficacy and adverse effects like abuse liability, and there is a dire need for novel analgesics with improved safety profiles. Since lysophosphatidic acid can induce neuropathic pain in rodents, LPA receptor antagonists have been investigated as potential analgesics ...
Kristen L. Woodhouse   +6 more
wiley   +1 more source

Pulmonary infection by non-tuberculous mycobacteria in an endemic region for tuberculosis in Northeast Brazil. [PDF]

open access: yesBraz J Med Biol Res
Lima AS   +6 more
europepmc   +1 more source

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