Results 11 to 20 of about 3,839,668 (166)

Yield of routine mycobacterial culture of osteoarticular specimens in a tertiary orthopaedic hospital in England, 2017–2022 [PDF]

Journal of Bone and Joint Infection
Introduction: At our tertiary orthopaedic centre, mycobacterial cultures are routinely performed on bone and joint samples sent for bacterial culture. Methods: From laboratory records, we ascertained the number of mycobacterial cultures performed, the ...
T. A. Yates, T. A. Yates, T. A. Yates, O. Vahesan, S. Warren, S. Warren, A. Scobie, A. Scobie, A. Scobie   +8 more
doaj   +4 more sources

Direct comparison of Xpert MTB/RIF assay with liquid and solid mycobacterial culture for quantification of early bactericidal activity [PDF]

, 2013
Contains fulltext : 119262.pdf (Publisher’s version ) (Open Access)The early bactericidal activity of antituberculosis agents is usually determined by measuring the reduction of the sputum mycobacterial load over time on solid agar ...
Boeree, M.J., Diacon, A.H., Boeree, Martin J., Hoelscher, M., Venter, Amour, Friedrich, S.O., Diacon, Andreas H., Kayigire, X.A., Heinrich, Norbert, Hoelscher, Michael, Gillespie, Stephen Henry, Gillespie, S.H., Dawson, Rodney, Venter, A., Kayigire, Xavier A., Heinrich, N., Aarnoutse, R.E., Dawson, R., et al., Friedrich, Sven O.   +19 more
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Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases [PDF]

, 2009
Background - There is an urgent need for the discovery and development of new drugs against Mycobacterium tuberculosis, the causative agent of tuberculosis, especially due to the recent emergence of multi-drug and extensively-drug resistant strains ...
Gurdyal S Besra, Alistair K. Brown, Bhatt, Apoorva; id_orcid, Apoorva Bhatt, Bhatt Apoorva, Besra, Gurdyal; id_orcid, Klaus Fütterer, Besra, Gurdyal, Futterer, Klaus, Taylor, Rebecca, Rebecca C Taylor, Fütterer Klaus, Besra Gurdyal S., Bhatt, Apoorva, Alistair K Brown, Taylor Rebecca C., Rebecca C. Taylor, Gurdyal S. Besra, Brown Alistair K., Brown, Alistair   +19 more
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Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]

, 2016
Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
Jugheli, Levan, Mohamed Sasamalo, Chande, Hassan, Maira Bholla, Beck, Hans-Peter, Reither, Klaus, Edward Masika, Tracy R. Glass, Hans-Peter Beck, Masika, Edward, Sasamalo, Mohamed, Glass, Tracy R., Klaus Reither, Bholla, Maira, Levan Jugheli, Kapalata, Neema, Hassan Chande, Neema Kapalata   +17 more
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Mycobacterium fortuitum Infection at Umbilical Hernioplasty Site [PDF]

Journal of Clinical and Diagnostic Research, 2017
Non Tuberculous Mycobacteria (NTM) are a group of rapidly growing mycobacteria and are generally considered to be of low virulence. Of late, there has been an increase in incidence of infections due to these organisms.
Bharti Chogtu, Daliparty Vasudev Malik, Rahul Magazine, Vishnu Prasad Shenoy   +3 more
doaj   +1 more source

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target [PDF]

, 2014
The human pathogen Mycobacterium tuberculosis is the causative agent of pulmonary tuberculosis (TB), a disease with high worldwide mortality rates. Current treatment programs are under significant threat from multi-drug and extensively-drug resistant ...
VijayaShankar Nataraj, Reynolds Robert C., Nicholas J Loman, Lloyd, AJ, Besra, Gurdyal S., Klaus Fütterer, Ballell, L, Reynolds, Robert C., Abrahams, Katherine A, Loman, Nicholas J., Hobrath Judith V., Gurcha Sudagar S., Alderwick, LJ, Abrahams, Katherine A., Gurcha, SS, Cox, Jonathan A G, Abrahams Katherine A., Hobrath, JV, Loman, Nicholas J, Carlos Alemparte, Lluis Ballell, Bhatt, Apoorva; id_orcid, Cox Jonathan A. G., Loman, NJ, Besra, GS, Reynolds, Robert C, Alemparte Carlos, Alderwick, Luke J, Gurcha, Sudagar S, Besra, Gurdyal S; id_orcid, Abrahams, KA, Besra Gurdyal S., Hobrath, Judith V, Barros, D, Robert C Reynolds, Loman Nicholas J., Bhatt, A, Ballell, Lluis, Nataraj, VijayaShankar, Lloyd, Adrian J., Apoorva Bhatt, Bhatt Apoorva, Nataraj, V, Alemparte, Carlos, Lloyd, Adrian J, Fütterer, K, Hobrath, Judith V., Veeraraghavan Usha, Cox, Jonathan A. G., Cox, JA, Barros David, Veeraraghavan, Usha, Bhatt, Apoorva, Adrian J Lloyd, Jonathan A G Cox, Usha, V, Gurdyal S Besra, David Barros, Lloyd Adrian J., Reynolds, RC, Alderwick, Luke J., Ballell Lluis, Usha Veeraraghavan, Fütterer Klaus, Barros, David, Nataraj, Vijaya-Shankar, Luke J Alderwick, Gurcha, Sudagar S., Alderwick Luke J., Judith V Hobrath, Sudagar S Gurcha, Usha, Veeraraghavan, Nataraj VijayaShankar, Alemparte, C, Fütterer, Klaus, Katherine A Abrahams   +75 more
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Blood cultures for the diagnosis of multidrug-resistant and extensively drug-resistant tuberculosis among HIV-infected patients from rural South Africa: a cross-sectional study

BMC Infectious Diseases, 2010
Background The yield of mycobacterial blood cultures for multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB) among drug-resistant TB suspects has not been described.
Eksteen François J, Moll Anthony P, Gandhi Neel R, Thomas Tania A, Heysell Scott K, Coovadia Yacoob, Roux Lynette, Babaria Palav, Lalloo Umesh, Friedland Gerald, Shah Sarita   +10 more
doaj   +1 more source

Evaluation of the Ogawa-Kudoh method for tuberculosis isolation in two health units in Mozambique

African Journal of Laboratory Medicine, 2020
Background: Mozambique is among the highest tuberculosis, tuberculosis–HIV and multidrug-resistant-tuberculosis burden countries. Although molecular technologies are available in-country, mycobacterial isolation through culture remains an important tool ...
Carla M. Madeira, Khalide I. Azam, Daisy N. Sato, Celso Khosa, Nilesh Bhatt, Sofia O. Viegas   +5 more
doaj   +1 more source

Accuracy of Xpert MTB/RIF Ultra for the diagnosis of tuberculosis in adult patients: a retrospective cohort study

International Journal of Infectious Diseases, 2022
Objectives: The value of the “trace” result in Xpert Ultra for diagnosing active tuberculosis (TB) remains unclear. Our study evaluated the diagnostic accuracy of Xpert MTB/RIF Ultra (Xpert Ultra) (Cepheid, Sunnyvale, USA) over Xpert MTB/RIF (Xpert ...
Chintan Kaswala, Yvonne Schmiedel, Debasree Kundu, Mithun Mohan George, Divya Dayanand, Emily Devasagayam, Abi Manesh S, Selwyn Selva Kumar, Joy S Michael, Marilyn M Ninan, Geeta Chacko, Anand Zachariah, Sowmya Sathyendra, Samuel George Hansdak, Ramya Iyadurai, Devasahayam Jesudas Christopher, Richa Gupta, Rajiv Karthik, Ooriapadickal Cherian Abraham, George M Varghese   +19 more
doaj   +1 more source

Ribosome profiling enhances understanding of mycobacterial translation [PDF]

, 2022
A recent addition to the -omics toolkit, ribosome profiling, enables researchers to gain insight into the process and regulation of translation by mapping fragments of mRNA protected from nuclease digestion by ribosome binding. In this review, we discuss
Sawyer, E.B., Cortes, T.
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