Results 31 to 40 of about 3,839,668 (166)

Development of new molecular genetic tools to study "Mycobacterium ulcerans" infection (Buruli ulcer) [PDF]

, 2005
Buruli ulcer is an infectious disease caused by an environmental pathogen, Mycobacterium ulcerans, which is the third major mycobacterial pathogen of man, after M. tuberculosis and M. leprae.
Rondini, Simona
core   +1 more source

Multicenter study of the performance of NTM Elite agar for the detection of nontuberculous mycobacteria from patients with cystic fibrosis

Microbiology Spectrum
The performance of a novel selective agar was evaluated against the performance of conventional mycobacterial cultures, i.e., a combination of the mycobacterial growth indicator tube (MGIT) with Löwenstein-Jensen (LJ), for the detection of nontuberculous
Emmanuel André, Natalie Lorent, Kurt Beuselinck, Susanne Deiwick, Lieven Dupont, Johanne Gafsi, Lies Laenen, Lise Raymaekers, Pascal Van Bleyenbergh, John D. Perry, Barbara C. Kahl   +10 more
doaj   +1 more source

Evaluation of a novel biphasic culture medium for recovery of mycobacteria: a multi-center study. [PDF]

PLoS ONE, 2012
BACKGROUND: Mycobacterial culture and identification provide a definitive diagnosis of TB. Culture on Löwenstein-Jensen (L-J) medium is invariably delayed because of the slow growth of M. tuberculosis on L-J slants.
Zhenling Cui, Jie Wang, Changtai Zhu, Xiaochen Huang, Junmei Lu, Qing Wang, Zhongnan Chen, Junling Wang, Yan Zhang, Delin Gu, Lingjie Jing, Jin Chen, Ruijuan Zheng, Lianhua Qin, Hua Yang, Ruiliang Jin, Zhonghua Liu, Aixiao Bi, Jinming Liu, Zhongyi Hu   +19 more
doaj   +1 more source

Mycobacterial lysocardiolipin is exported from phagosomes upon cleavage of cardiolipin by a macrophage-derived lysosomal phospholipase A2. [PDF]

, 2001
Pathogenic mycobacteria are able to survive and proliferate in phagosomes within host macrophages (Mphi). This capability has been attributed in part to their cell wall, which consists of various unique lipids.
Torrelles, Jordi, Torrelles, J., Schaible, UE, Fischer, K, Kaufmann, Stefan H. E., Chatterjee, D., Brennan, Patrick J., Chatterjee, D, Fischer, K., Brennan, PJ, Schaible, U., Brennan, P., Torrelles, J, Kaufmann, S., Fischer, Karsten, Kaufmann, SH, Chatterjee, Delphi, Schaible, Ulrich E.   +17 more
core   +1 more source

Osteoarticular tuberculosis – diagnostic solutions in a disease endemic region

Journal of Infection in Developing Countries, 2009
Background: We conducted a study of osteoarticular tuberculosis in patients from private and public settings in a disease endemic area. Our objective was to assess the role of mycobacterial culture and polymerase chain reaction (PCR) in the diagnosis of ...
Vikas Agashe, Shubhada Shenai, Ganesh Mohrir, Minal Deshmukh, Anita Bhaduri, Ramesh Deshpande, Ajita Mehta, Camilla Rodrigues   +7 more
doaj   +1 more source

Antigen 85B peptidomic analysis allows species-specific mycobacterial identification

Clinical Proteomics, 2018
Background Nontuberculous mycobacteria (NTM)-mediated infections are a growing cause of worldwide morbidity, but lack of rapid diagnostics for specific NTM species can delay the initiation of appropriate treatment regimens.
Wei Zhang, Qingbo Shu, Zhen Zhao, Jia Fan, Christopher J. Lyon, Adrian M. Zelazny, Ye Hu   +6 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Insights into mycobacteriome composition in Mycobacterium bovis-infected African buffalo (Syncerus caffer) tissue samples

Scientific Reports
Animal tuberculosis significantly challenges global health, agriculture, and wildlife conservation efforts. Mycobacterial cultures are resource-intensive, time-consuming, and challenged by heterogeneous populations.
Giovanni Ghielmetti, Tanya J. Kerr, Netanya Bernitz, Sinegugu K. Mhlophe, Elizma Streicher, Andre G. Loxton, Robin M. Warren, Michele A. Miller, Wynand J. Goosen   +8 more
doaj   +1 more source

rpoB Targeted Loop-Mediated Isothermal Amplification (LAMP) Assay for Consensus Detection of Mycobacteria Associated With Pulmonary Infections

Frontiers in Medicine, 2018
Loop-mediated isothermal amplification (LAMP) is a nucleic acid method which has been used to identify mycobacteria including Mycobacterium tuberculosis in clinical microbiology laboratory and point of care settings.
Simon Grandjean Lapierre, Simon Grandjean Lapierre, Michel Drancourt   +2 more
doaj   +1 more source