Results 1 to 10 of about 530,034 (290)

A universal, high-quality, and high-yield DNA purification method for mycobacteria, including Mycobacterium tuberculosis: large-scale assessment of the chloroform-bead method [PDF]

Microbiology Spectrum
Genomic analysis of mycobacteria has become increasingly crucial for understanding drug-resistance mechanisms, molecular epidemiology, and pathogenesis.
Yoshiro Murase, Makiko Hosoya, Yuta Morishige, Yoshiko Shimomura, Miori Nagai, Aki Tamaru, Akiko Takaki, Satoshi Mitarai   +7 more
doaj   +2 more sources

Mycobacterial Spindle Cell Pseudotumor Presenting as a Pancreatic Head Mass: A Case Report [PDF]

Pathogens
Mycobacterial spindle cell pseudotumors (MSCPs) are rare lesions characterized by the proliferation of spindle-shaped histiocytes caused by mycobacterial infections.
Frank A Cusimano, Tara Herrera, Douglas Brust, Elizabeth Montgomery, Sunil Amin, Folusakin Ayoade   +5 more
doaj   +2 more sources

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages [PDF]

, 2008
This study provides the proof of principle that probing the host and the microbe transcriptomes simultaneously is a valuable means to accessing unique information on host pathogen interactions.
A Kolb-Maurer, A Kumar, A Savina, A Yamauchi, A Yoshimura, Alessandra Mortellaro, AM Talaat, AM Talaat, Antoine Tanne, B Hutter, B Pron, BM Bolstad, Brigitte Gicquel, C Nathan, CH Wang, D Chaussabel, D Lombardi, D Schnappinger, D Schnappinger, D Werling, Derya Unutmaz, DG Russell, DJ Beste, DM Roberts, E Giacomini, E Werner, F Niedergang, FS Machado, G Cappelli, G Harth, G Sulzenbacher, GJ Nau, GK Smyth, GK Smyth, GR Stewart, H Ohno, H Rachman, HD Park, I Vergne, J Bacon, JA Mangan, JC Betts, JC Boldrick, JD McKinney, JP Wang, L Shi, L Tailleux, LP Barker, LR Camacho, Ludovic Tailleux, M Kanehisa, M Kanehisa, M Pelizzola, MA Harris, Maria Foti, Mattia Pelizzola, MB Eisen, MI Voskuil, Michael Withers, MM Westcott, MV Tullius, N Mohagheghpour, Neil G. Stoker, Olivier Neyrolles, P Ricciardi-Castagnoli, Paola Ricciardi Castagnoli, PC Karakousis, Philip D. Butcher, R Van der Geize, RA Henderson, RA Irizarry, S Ehrt, S Nicholson, S Ragno, S Stenger, S Sturgill-Koszycki, Simon J. Waddell, SJ Waddell, SJ Waddell, SL Kendall, SL Kendall, ST Cole, T Kawai, T Parish, X Jiao, Y Hu, Y Yuan   +86 more
core   +44 more sources

Transcription Repressor Protein ZBTB25 Associates with HDAC1-Sin3a Complex in Mycobacterium tuberculosis-Infected Macrophages, and Its Inhibition Clears Pathogen by Autophagy

mSphere, 2021
Following infection with M.
Aravind Madhavan, K. B. Arun, Akhil Raj Pushparajan, M. Balaji, Ramakrishnan Ajay Kumar   +4 more
doaj   +1 more source

Anti-Mycobacterial Drug Resistance in Japan: How to Approach This Problem?

Antibiotics, 2021
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberculosis mycobacteria (NTM). The pathogens cause not only respiratory infections, but also general diseases.
Keisuke Kamada, Satoshi Mitarai
doaj   +1 more source

Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis

Scientific Reports, 2021
Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that can adapt to the various nutrients available during its life cycle. However, in the nutritionally stringent environment of the macrophage phagolysosome, Mtb relies mainly on cholesterol.
Jakub Pawełczyk, Anna Brzostek, Alina Minias, Przemysław Płociński, Anna Rumijowska-Galewicz, Dominik Strapagiel, Jolanta Zakrzewska-Czerwińska, Jarosław Dziadek   +7 more
doaj   +1 more source

Cobalamin is present in cells of non-tuberculous mycobacteria, but not in Mycobacterium tuberculosis

Scientific Reports, 2021
Cobalamin (vitamin B12) is a structurally complex molecule that acts as a cofactor for enzymes and regulates gene expression through so-called riboswitches.
Alina Minias, Filip Gąsior, Anna Brzostek, Tomasz Jagielski, Jarosław Dziadek   +4 more
doaj   +1 more source

L-Tyrosine Limits Mycobacterial Survival in Tuberculous Granuloma

Pathogens, 2023
Caused by the intracellular pathogen Mycobacterium tuberculosis (Mtb), tuberculosis (TB) remains a massive global public health issue. A well-known and key TB trait is caseous necrotic granuloma, which allows mycobacteria to reactivate and disseminate ...
Yaxian Gao, Jiaqing Li, Xinya Guo, Liru Guan, Jie Wang, Xiaochen Huang, Wenjuan Wang, Hua Yang   +7 more
doaj   +1 more source

GENE MUTATION PATTERNS OF RIFAMPICIN IN MULTIDRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS COMPLEX STRAINS

İstanbul Tıp Fakültesi Dergisi, 2022
Objective: The aim of this study was to evaluate the GenoType®MTBDRplus test for detection of rifampicin (RIF) resistance in MDR Mycobacterium tuberculosis complex strains.
Esra Yıldırım Servi, Meltem Uzun
doaj   +1 more source

Characteristics and diseases associations of tuberculosis in lupus: A retrospective single-center analysis

Indian Journal of Rheumatology, 2022
Objective: The objective of this study is to identify factors associated with active tuberculosis (TB) in patients with systemic lupus erythematosus (SLE) and to study the impact of TB on SLE disease activity. Methodology: We screened case records of 643
Dunga Sai Kumar, Sanket Ishwarbhai Shah, Chengappa Kavadichanda, Aishwarya Gopal, Prakash Babu Narasimhan, Vir Singh Negi   +5 more
doaj   +1 more source