Results 1 to 10 of about 541,488 (343)

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages [PDF]

, 2008
This study provides the proof of principle that probing the host and the microbe transcriptomes simultaneously is a valuable means to accessing unique information on host pathogen interactions.
A Kolb-Maurer, A Kumar, A Savina, A Yamauchi, A Yoshimura, Alessandra Mortellaro, AM Talaat, AM Talaat, Antoine Tanne, B Hutter, B Pron, BM Bolstad, Brigitte Gicquel, C Nathan, CH Wang, D Chaussabel, D Lombardi, D Schnappinger, D Schnappinger, D Werling, Derya Unutmaz, DG Russell, DJ Beste, DM Roberts, E Giacomini, E Werner, F Niedergang, FS Machado, G Cappelli, G Harth, G Sulzenbacher, GJ Nau, GK Smyth, GK Smyth, GR Stewart, H Ohno, H Rachman, HD Park, I Vergne, J Bacon, JA Mangan, JC Betts, JC Boldrick, JD McKinney, JP Wang, L Shi, L Tailleux, LP Barker, LR Camacho, Ludovic Tailleux, M Kanehisa, M Kanehisa, M Pelizzola, MA Harris, Maria Foti, Mattia Pelizzola, MB Eisen, MI Voskuil, Michael Withers, MM Westcott, MV Tullius, N Mohagheghpour, Neil G. Stoker, Olivier Neyrolles, P Ricciardi-Castagnoli, Paola Ricciardi Castagnoli, PC Karakousis, Philip D. Butcher, R Van der Geize, RA Henderson, RA Irizarry, S Ehrt, S Nicholson, S Ragno, S Stenger, S Sturgill-Koszycki, Simon J. Waddell, SJ Waddell, SJ Waddell, SL Kendall, SL Kendall, ST Cole, T Kawai, T Parish, X Jiao, Y Hu, Y Yuan   +86 more
core   +20 more sources

Transcription Repressor Protein ZBTB25 Associates with HDAC1-Sin3a Complex in Mycobacterium tuberculosis-Infected Macrophages, and Its Inhibition Clears Pathogen by Autophagy

mSphere, 2021
Following infection with M.
Aravind Madhavan, K. B. Arun, Akhil Raj Pushparajan, M. Balaji, Ramakrishnan Ajay Kumar   +4 more
doaj   +1 more source

Desiccation-Tolerance of Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium chimaera, Mycobacterium abscessus and Mycobacterium chelonae

Pathogens, 2022
Desiccation-tolerance of cells of four strains of Mycobacterium chimaera and individual strains of Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium abscessus, and Mycobacterium chelonae were measured by two methods. The survival of water-acclimated cells both in filter paper and on the surface of stainless-steel coupons were measured ...
Joseph O. Falkinham, Myra D. Williams
openaire   +4 more sources

Mycobacterium biofilms

Biofilm, 2023
The genus Mycobacterium includes some of the deadliest pathogens of History (Mycobacterium tuberculosis, Mycobacterium leprae), but most of the species within the genus are environmental microorganisms. Because some of these nontuberculous mycobacteria (NTM) species can be human pathogens, the study of these mycobacterial biofilms has increased during ...
Maria-Carmen Muñoz-Egea, Arij Akir, Jaime Esteban   +2 more
openaire   +3 more sources

Mycobacterium abscessus

Trends in Microbiology, 2021
No abstract ...
Boudehen, Yves-Marie, Kremer, Laurent
openaire   +3 more sources

Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis

Scientific Reports, 2021
Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that can adapt to the various nutrients available during its life cycle. However, in the nutritionally stringent environment of the macrophage phagolysosome, Mtb relies mainly on cholesterol.
Jakub Pawełczyk, Anna Brzostek, Alina Minias, Przemysław Płociński, Anna Rumijowska-Galewicz, Dominik Strapagiel, Jolanta Zakrzewska-Czerwińska, Jarosław Dziadek   +7 more
doaj   +1 more source

Anti-Mycobacterial Drug Resistance in Japan: How to Approach This Problem?

Antibiotics, 2021
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberculosis mycobacteria (NTM). The pathogens cause not only respiratory infections, but also general diseases.
Keisuke Kamada, Satoshi Mitarai
doaj   +1 more source

Cobalamin is present in cells of non-tuberculous mycobacteria, but not in Mycobacterium tuberculosis

Scientific Reports, 2021
Cobalamin (vitamin B12) is a structurally complex molecule that acts as a cofactor for enzymes and regulates gene expression through so-called riboswitches.
Alina Minias, Filip Gąsior, Anna Brzostek, Tomasz Jagielski, Jarosław Dziadek   +4 more
doaj   +1 more source

L-Tyrosine Limits Mycobacterial Survival in Tuberculous Granuloma

Pathogens, 2023
Caused by the intracellular pathogen Mycobacterium tuberculosis (Mtb), tuberculosis (TB) remains a massive global public health issue. A well-known and key TB trait is caseous necrotic granuloma, which allows mycobacteria to reactivate and disseminate ...
Yaxian Gao, Jiaqing Li, Xinya Guo, Liru Guan, Jie Wang, Xiaochen Huang, Wenjuan Wang, Hua Yang   +7 more
doaj   +1 more source

GENE MUTATION PATTERNS OF RIFAMPICIN IN MULTIDRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS COMPLEX STRAINS

İstanbul Tıp Fakültesi Dergisi, 2022
Objective: The aim of this study was to evaluate the GenoType®MTBDRplus test for detection of rifampicin (RIF) resistance in MDR Mycobacterium tuberculosis complex strains.
Esra Yıldırım Servi, Meltem Uzun
doaj   +1 more source