Results 11 to 20 of about 530,034 (290)

Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial. [PDF]

, 2020
BACKGROUND: Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia.
Abass, KM, Agossadou, D, Ampadu, EO, Asiedu, KB, Chauty, A, Egondi, TW, Frimpong, M, Ganlonon, L, Gateau, T, Grosset, J, Lehman, L, Macdonald, JM, Marion, E, Ochieng Otieno, M, Ohene, S-A, Omollo, R, Paintsil, A, Phillips, RO, Robert, J, Saizonou, R, Sarfo, FS, Sarpong, G, Sarpong, NF, Saunderson, P, Stienstra, Y, study team, Thompson, W, Tiendrebeogo, A, Treadwell, T, van der Werf, TS, Wansbrough-Jones, M, Wilson, T   +31 more
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Functional Disassociation Between the Protein Domains of MSMEG_4305 of Mycolicibacterium smegmatis (Mycobacterium smegmatis) in vivo

Frontiers in Microbiology, 2020
MSMEG_4305 is a two-domain protein of Mycolicibacterium smegmatis (Mycobacterium smegmatis) (Mycolicibacterium smegmatis). The N-terminal domain of MSMEG_4305 encodes an RNase H type I.
Bożena Czubat, Bożena Czubat, Alina Minias, Anna Brzostek, Anna Żaczek, Katarzyna Struś, Jolanta Zakrzewska-Czerwińska, Jarosław Dziadek   +7 more
doaj   +1 more source

Draft Genome Sequence of Mycobacterium obuense Strain UC1, Isolated from Patient Sputum. [PDF]

, 2015
We report the draft genome sequence of Mycobacterium obuense strain UC1 from a patient sputum sample. This is the first draft genome sequence of Mycobacterium obuense, a rapidly growing scotochromogenic ...
Chiu, Charles Y, Cunningham, Gail, Greninger, Alexander L, Hsu, Elaine D, Miller, Steve, Yu, Joanna M   +5 more
core   +2 more sources

Polymorphism in the EREG gene confers susceptibility to tuberculosis

BMC Medical Genetics, 2019
Background Host genetic factors affect the immune response to Mycobacterium tuberculosis (Mtb) infection as well as the progression of the disease. Epiregulin (EREG) belongs to the epidermal growth factor (EGF) family, which binds to the epidermal growth
Wen Cao, Liu-lin Luo, Wei-wei Chen, Li Liang, Ran-ran Zhang, Yan-lin Zhao, Jin Chen, Jun Yue   +7 more
doaj   +1 more source

An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]

, 2005
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS, Colston, MJ, Curry, JM, Gohil, K, Hunt, DM, Rickman, L, Smerdon, SJ, Strom, M, Whalan, R   +8 more
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DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin   +117 more
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Mycolicibacterium smegmatis, Basonym Mycobacterium smegmatis, Expresses Morphological Phenotypes Much More Similar to Escherichia coli Than Mycobacterium tuberculosis in Quantitative Structome Analysis and CryoTEM Examination

Frontiers in Microbiology, 2018
A series of structome analyses, that is, quantitative and three-dimensional structural analysis of a whole cell at the electron microscopic level, have already been achieved individually in Exophiala dermatitidis, Saccharomyces cerevisiae, Mycobacterium ...
Hiroyuki Yamada, Masashi Yamaguchi, Yuriko Igarashi, Kinuyo Chikamatsu, Akio Aono, Yoshiro Murase, Yuta Morishige, Akiko Takaki, Hiroji Chibana, Satoshi Mitarai, Satoshi Mitarai   +10 more
doaj   +1 more source

Something Old, Something New: Ion Channel Blockers as Potential Anti-Tuberculosis Agents

Frontiers in Immunology, 2021
Tuberculosis (TB) remains a challenging global health concern and claims more than a million lives every year. We lack an effective vaccine and understanding of what constitutes protective immunity against TB to inform rational vaccine design.
Steven C. Mitini-Nkhoma, Elizabeth T. Chimbayo, David T. Mzinza, David T. Mzinza, David V. Mhango, David V. Mhango, Aaron P. Chirambo, Christine Mandalasi, Agness E. Lakudzala, Dumizulu L. Tembo, Kondwani C. Jambo, Kondwani C. Jambo, Henry C. Mwandumba, Henry C. Mwandumba   +13 more
doaj   +1 more source

Lipoproteins of Mycobacterium tuberculosis : an abundant and functionally diverse class of cell envelope components [PDF]

, 2004
Mycobacterium tuberculosis remains the predominant bacterial scourge of mankind. Understanding of its biology and pathogenicity has been greatly advanced by the determination of whole genome sequences for this organism.
Harrington, Dean, Sutcliffe, Iain
core   +1 more source

Tuberculosis in Dr Granville's mummy: a molecular re-examination of the earliest known Egyptian mummy to be scientifically examined and given a medical diagnosis [PDF]

, 2010
‘Dr Granville's mummy’ was described to the Royal Society of London in 1825 and was the first ancient Egyptian mummy to be subjected to a scientific autopsy.
Abu Al-Soud W., Boom R., David E. Minnikin, Forbes B. A., Granville A. B., Gurdyal S. Besra, Harer W. B., Helen D. Donoghue, Hellyer T. J., John H. Taylor, Mark Spigelman, Minnikin D. E., Oona Y.-C. Lee, Tapp E., Taylor G. M., Taylor G. M.   +15 more
core   +2 more sources