Results 241 to 250 of about 648,089 (387)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Extrapulmonary Comparisons Between <i>Mycobacterium Tuberculosis</i> and Non-Tuberculous Mycobacteria: From Manifestations and Diagnosis to Treatment. [PDF]

Infect Drug Resist
Dong Q, Wang M, Wang Z, Shi J, Xie J, Li X, Liu C, Chen Y, Guo S.   +8 more
europepmc   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection

Nature reviews. Immunology, 2018
Jason D. Simmons, Catherine M. Stein, C. Seshadri, M. Campo, G. Alter, S. Fortune, E. Schurr, R. Wallis, G. Churchyard, H. Mayanja-Kizza, W. Boom, T. Hawn   +11 more
semanticscholar   +1 more source

Treponema pallidum Protein Tp0136 Induces Spheroidization of Vascular Endothelial Cells, Resulting in Widened Intercellular Junctions and Enhanced Vascular Permeability

Small Science, EarlyView.
Treponema pallidum protein Tp0136 enhances vascular permeability by upregulating CSRP1, which induces MYO10 exon 19 skipping, reducing MYO10 expression and triggering endothelial spheroidization. This study reveals a novel RNA splicing‐mediated dissemination mechanism, proposing CSRP1/MYO10 as therapeutic targets to limit bacterial dissemination in ...
Yu Lin, Xi Luo, Xu Shen, Xiao‐Lin Fu, Li‐Rong Lin, Tian‐Ci Yang   +5 more
wiley   +1 more source

Changes in Morphology of an Avirulent Strain of Mycobacterium tuberculosis under the influence of Non-ionic Surface-active Agents

, 1954
P. D’Arcy Hart, R. J. W. Rees
openalex   +1 more source

BIOLOGICAL STUDIES ON MYCOBACTERIUM ULCERANS (MACCALLUM) [PDF]

, 1958
H Yaoi, M Takei, Yuzuru Tsuji
openalex   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

Small Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han, Jieyun Xu, Xinyu Guo, Lingyu Liang, Linjun Zhang, Yu Su, Wendong Gao, Qingming Tang, Lili Chen, Zhuofan Chen, Yin Xiao, Zetao Chen   +11 more
wiley   +1 more source

<i>Mycobacterium appelbergii</i> sp. nov., a Novel Species Isolated from a Drinking Water Fountain in a Rural Community. [PDF]

Microorganisms
Roxo IC, Alarico S, Fonseca A, Machado D, Maranha A, Tiago I, Duarte R, Empadinhas N.   +7 more
europepmc   +1 more source

Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium

Science, 2016
J. Bryant, D. Grogono, D. Rodriguez-Rincon, I. Everall, Karen P. Brown, P. Moreno, D. Verma, E. Hill, J. Drijkoningen, P. Gilligan, C. Esther, P. Noone, O. Giddings, S. Bell, R. Thomson, C. Wainwright, C. Coulter, S. Pandey, M. Wood, R. Stockwell, K. Ramsay, L. Sherrard, T. Kidd, Nassib Jabbour, G. Johnson, L. Knibbs, L. Morawska, P. Sly, Andrew L Jones, D. Bilton, I. Laurenson, Michael Ruddy, S. Bourke, I. Bowler, S. Chapman, A. Clayton, M. Cullen, O. Dempsey, M. Denton, M. Desai, Richard J. Drew, F. Edenborough, J. Evans, J. Folb, T. Daniels, H. Humphrey, B. Isalska, S. Jensen-Fangel, B. Jönsson, A. Jones, T. Katzenstein, T. Lillebaek, G. MacGregor, S. Mayell, M. Millar, D. Modha, E. Nash, C. O'Brien, D. O'Brien, C. Ohri, C. Pao, D. Peckham, F. Perrin, A. Perry, T. Pressler, L. Prtak, T. Qvist, A. Robb, H. Rodgers, K. Schaffer, N. Shafi, J. van Ingen, M. Walshaw, Danie Watson, N. West, J. Whitehouse, C. Haworth, S. Harris, D. Ordway, J. Parkhill, R. Floto   +80 more
semanticscholar   +1 more source