Results 61 to 70 of about 172,337 (220)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Spatio-temporal distribution of Mycobacterium tuberculosis complex strains in Ghana [PDF]

, 2016
BACKGROUND: There is a perception that genomic differences in the species/lineages of the nine species making the Mycobacterium tuberculosis complex (MTBC) may affect the efficacy of distinct control tools in certain geographical areas.
Yeboah-Manu, Dorothy, K. A. Koram (3088575), Asante-Poku, A., S. Osei-Wusu (3088569), I. D. Otchere (3088587), Forson, A., Dorothy Yeboah-Manu (120059), Osei-Wusu, S., Gagneux, Sebastien, Danso, E., A. Forson (3088581), A. Asante-Poku (3088584), I D Otchere, E. Danso (3088578), A Asante-Poku, Asare, P., P Asare, Koram, K. A., S Osei-Wusu, E Danso, Sebastien Gagneux (149824), A Forson, K A Koram, Sebastien Gagneux, P. Asare (3088572), Dorothy Yeboah-Manu, Otchere, I. D.   +26 more
core   +1 more source

Low Prevalence of Mycobacterium bovis in Tuberculosis Patients, Ethiopia

Emerging Infectious Diseases, 2020
An estimated 17% of all tuberculosis cases in Ethiopia are caused by Mycobacterium bovis. We used M. tuberculosis complex isolates to identify the prevalence of M. bovis as the cause of pulmonary tuberculosis. Our findings indicate that the proportion of
Muluwork Getahun, H.M. Blumberg, Waganeh Sinshaw, Getu Diriba, Hilina Mollalign, Ephrem Tesfaye, Bazezew Yenew, Mengistu Taddess, Aboma Zewdie, Kifle Dagne, Dereje Beyene, Russell R. Kempker, Gobena Ameni   +12 more
doaj   +1 more source

MMP9 Knockout by CRISPR‐Cas9 Reduces Bladder Cancer Malignancy But Does Not Synergize With BCG and Anti‐PD‐L1 in an Orthotopic Mouse Model

IUBMB Life, Volume 78, Issue 9, September 2026.
ABSTRACT Bladder cancer (BC) is the 10th most common cancer worldwide, accounting for approximately 5% of new cases. Several factors contribute to tumor progression, including increased MMP9. Recently, CRISPR‐Cas9 and immunotherapy have offered high specificity for treatments; therefore, we edited MMP9 using CRISPR‐Cas9 methodology to inhibit ...
Juliana Alves de Camargo, Maria Carolina Lee, Milena Monteiro de Souza, Luana Pereira da Silva, Giovanna Caetano Vilas Boas, Karina Serafim da Silva, Carolina Mie Mioshi, Ruan Cesar Aparecido Pimenta, Patrícia Candido, Iran Amorim da Silva, Ericka Barbosa Trarbach, Katia Ramos Moreira Leite, William Carlos Nahas, Sabrina Thalita dos Reis   +13 more
wiley   +1 more source

Differences in primary sites of infection between zoonotic and human tuberculosis : results from a worldwide systematic review [PDF]

, 2013
Tuberculosis (TB) is one of the most devastating infectious diseases worldwide. Whilst global burden estimates for M. tuberculosis infection (MtTB) are well established, accurate data on the contribution of zoonotic TB (zTB) caused by M.
Alonso Silvia, Helden, P.D. van, Müller Borna, Durr, S, Paul D. van Helden (33594), Jan Hattendorf (113923), Dürr Salome, Borna Müller (173253), van Helden, P D, Salome Dürr (272199), Laisse, CJM, Hattendorf, J., Müller, B., Hattendorf, J, Zinsstag Jakob, Muller, B, Laisse, Cláudio J M, Cláudio J. M. Laisse (451813), Hattendorf Jan, Müller, Borna, Zinsstag, J, van Helden, P. D., Durr, Salome, van Helden, Paul D, Borna Müller, Paul D van Helden, Laisse, C. J. M., Silvia Alonso, Jakob Zinsstag (113928), van Helden Paul D., Salome Dürr, Laisse Cláudio J. M., Dürr, S., Dürr, Salome Esther, Zinsstag, Jakob, Alonso, Silvia, Hattendorf, Jan, Alonso, S, Laisse, Claudio J. M., Alonso, S., Van Helden, Paul D., Cláudio J M Laisse, Jakob Zinsstag, Laisse, C.J.M., Zinsstag, J., Jan Hattendorf, Silvia Alonso (451812)   +46 more
core   +2 more sources

Spoligtyping e polimorfismo do gene pncA: Um cenário em duas etapas para o diagnóstico de Mycobacterium bovis em Portugal

Revista Portuguesa de Pneumologia, 2005
Resumo: O diagnóstico diferencial do Mycobacterium bovis é importante no controlo da transmissão para a população humana e também no tratamento da doença, visto que o M. bovis é naturalmente resistente à pirazinamida.
Suzana David, Clara Portugal, Abílio Antunes, Ana Calado, Ângela Cardoso, Vanessa Barros, Luísa Sancho, José Germano de Sousa   +7 more
doaj   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf, Paul Nouri, Frédéric Galisson, Laetitia Daury, Marie‐France Giraud, Olivier Lambert, Cédric Orelle, Lionel Ballut, Elise Kaplan, Jean‐Michel Jault, Cécile Gonzalez   +10 more
wiley   +1 more source

Evidence for genetic variance in resistance to tuberculosis in Great Britain and Irish Holstein-Friesian populations [PDF]

, 2011
peer-reviewedBackground: Here, we jointly summarise scientific evidence for genetic variation in resistance to infection with Mycobacterium bovis, the primary agent of bovine tuberculosis (TB), provided by two recent and separate studies of Holstein ...
Downs, S. H., Mike Coffey, Andy P Mitchell, Bermingham, Mairead Lesley, White, Ian MS, Donagh P Berry, Bermingham, Mairead L, Downs Sara H, Stephen C Bishop, More, Simon J, Glass, Elizabeth, Woolliams, John, Cromie Andrew R, Simon J More, White, Ian, Isabella M Higgins, Bermingham Mairead L, Susan Brotherstone, M Higgans, I, Andrew R Cromie, More Simon J, Berry Donagh P, Berry, Donagh P., Good, Margaret, More, Simon, John A Woolliams, Mitchell Andy P, Richard S Clifton-Hadley, Mairead L Bermingham, et al., Glass Elizabeth J, Sara H Downs, Mitchell, Andy P, Woolliams John A, Coffey, M. P., Clifton-Hadley, R. S., Bishop Stephen C, Clifton-Hadley, Richard S, Coffey Mike, Higgins Isabella M, Good, M, Bermingham, Mairead L., Coffey, Mike P., Ian MS White, Cromie, A, Brotherstone, Susan, Higgins, Isabella, Cromie, A. R., White Ian MS, Elizabeth J Glass, Margaret Good, Mitchell, A. P., Bishop, Stephen, Good Margaret, Downs, Sara H, Bishop, Stephen C, Glass, Elizabeth J, P Berry, Donagh, Clifton-Hadley Richard S, Brotherstone Susan, Berry, Donagh, Woolliams, John A   +61 more
core   +1 more source

CCL2 responses to Mycobacterium tuberculosis are associated with disease severity in tuberculosis. [PDF]

, 2009
BACKGROUND Leucocyte activating chemokines such as CCL2, CCL3, and CXCL8 together with proinflammatory IFNgamma, TNFalpha and downmodulatory IL10 play a central role in the restriction of M.
Cliff, JM, Ashraf, M, Hussain, R, Hasan, Z, Dockrell, HM, Jamil, B, Irfan, M   +6 more
core   +3 more sources

Case Report: Use of extracorporeal support to treat a fulminant Mycobacterium bovis infection and complex broncho-oesophageal fistula in a child

Frontiers in Pediatrics
Tuberculosis (TB), caused by Mycobacterium tuberculosis remains a significant public health issue. Human TB caused by Mycobacterium bovis (M. bovis) is rare accounting for less than 1% of TB cases in UK annually.
Hussein Hussein, Richard Paget, Louis Grandjean, Alasdair Bamford, Ashwin Pandey, Katy Fidler, Claire Snowden, Arun Beeman, Pooja Shetty, Nagarajan Muthialu   +9 more
doaj   +1 more source