Metabolism of Mycobacterium leprae in macrophages [PDF]
The incorporation of 14C-labeled palmitic acid ( [U-14C]PA) into the phenolic glycolipid-I (PGL-I) fraction of Mycobacterium leprae was studied in a murine macrophage system in vitro. Peritoneal macrophages from Swiss Webster mice were infected with fresh viable or Formalin-killed M.
J L Krahenbuhl, N Ramasesh, R C Hastings
openaire +3 more sources
Intact Mycobacterium leprae Isolated from Placenta of a Pregnant Woman, China
Whether Mycobacterium leprae transmits from placenta to fetus remains unknown. We describe the case of a pregnant woman with untreated histoid leproma. Although her newborn was healthy, laboratory examination revealed intact M.
Zhiming Chen+8 more
doaj +1 more source
Foi feita revisão histórica sobre os corantes utilizados na identificação do Mycobacterium leprae. Foram analisadas para cada corante, sua composição química, propriedades tintoriais e a capacidade de assimilação pelo bacilo nas diversas técnicas de ...
Luiz Fernando de Góes Siqueira+2 more
doaj +1 more source
Fitting birth-death processes to panel data with applications to bacterial DNA fingerprinting [PDF]
Continuous-time linear birth-death-immigration (BDI) processes are frequently used in ecology and epidemiology to model stochastic dynamics of the population of interest. In clinical settings, multiple birth-death processes can describe disease trajectories of individual patients, allowing for estimation of the effects of individual covariates on the ...
arxiv +1 more source
Mycobacterium leprae in bone marrow
The case of a 54-year-old man, who was referred to evaluate a consumptive syndrome with anemia and fever of unknown origin, is reported. A physical examination revealed madarosis, nodular lesions on the ears, nasal soft tissue collapse, subcutaneous nodules on arms and generalized lymphadenopathy.
Oliveira, Leonardo Rodrigues de+1 more
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A Study of Qualitative Correlations Between Crucial Bio-markers and the Optimal Drug Regimen of Type-I Lepra Reaction: A Deterministic Approach [PDF]
Mycobacterium leprae is a bacteria that causes the disease Leprosy (Hansen's disease), which is a neglected tropical disease. More than 200000 cases are being reported per year world wide. This disease leads to a chronic stage known as Lepra reaction that majorly causes nerve damage of peripheral nervous system leading to loss of organs.
arxiv
Peptidoglycan and Arabinogalactan of Mycobacterium Leprae [PDF]
The arabinogalactan and peptidoglycan of armadillo-grown Mycobacterium leprae were examined. Within the limits defined by the small amount of material available, the resemblance of these polymers to those of other mycobacteria was confirmed. The polymers were linked by a highly acid-labile bond and the arabinogalactan was itself acid-labile; free ...
André Darbre+2 more
openaire +3 more sources
Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of ...
Diana Machado+13 more
doaj +1 more source
Avaliação da reação de mitsuda em pacientes virchovianos inativos antes e após imunoterapia
Neste estudo investigou-se o potencial imunomodulador do levamisole e da mistura BCG/Mycobacterium leprae em pacientes virchovianos inativos, utilizando como parâmetro a reação de Mitsuda.
Maria Sueli Parreira de Arruda+4 more
doaj +3 more sources
A Comprehensive and Detailed Within-Host Modeling Study involving crucial Bio markers and Optimal Drug regimen for Lepra Type-I Reaction : A Deterministic Approach [PDF]
Leprosy (Hansen's disease) is an infectious, neglected tropical disease caused by the Mycobacterium Leprae (M. Leprae). Each year there are approximately 2,02,189 new cases are detected globally. In the year 2017 more than half million people were disabled due to leprosy and almost 50000 new cases are added every year world wide.
arxiv