Results 11 to 20 of about 380,966 (308)

Polymorphism in the EREG gene confers susceptibility to tuberculosis

BMC Medical Genetics, 2019
Background Host genetic factors affect the immune response to Mycobacterium tuberculosis (Mtb) infection as well as the progression of the disease. Epiregulin (EREG) belongs to the epidermal growth factor (EGF) family, which binds to the epidermal growth
Wen Cao, Liu-lin Luo, Wei-wei Chen, Li Liang, Ran-ran Zhang, Yan-lin Zhao, Jin Chen, Jun Yue   +7 more
doaj   +1 more source

The Roles of Host Noncoding RNAs in Mycobacterium tuberculosis Infection

Frontiers in Immunology, 2021
Tuberculosis remains a major health problem. Mycobacterium tuberculosis, the causative agent of tuberculosis, can replicate and persist in host cells.
Li Wei, Kai Liu, Qingzhi Jia, Hui Zhang, Qingli Bie, Qingli Bie, Bin Zhang, Bin Zhang   +7 more
doaj   +1 more source

Mycobacterium tuberculosis lineage: a naming of the parts [PDF]

, 2005
There have been many reports of groups of related Mycobacterium tuberculosis strains described variously as lineages, families or clades. There is no objective definition of these groupings making it impossible to define relationships between those ...
Bellamy, Bhanu, Bifani, Brosch, Dale, Gillespie, Gillespie, Gillespie, Glynn, Kamerbeek, Kato-Maeda, L. Uiso, Maguire, McHugh, McHugh, Moss, R.D. Gosling, R.J. Shorten, S.H. Gillespie, S.L. Batt, Sola, Supply, T.D. McHugh, van Crevel, van Embden, Yeh   +25 more
core   +1 more source

A solitary pulmonary nodule caused by Mycobacterium tuberculosis var. BCG after intravesical BCG treatment: a case report

BMC Pulmonary Medicine, 2021
Background Intravesical instillation of bacillus Calmette–Guérin (BCG) as a treatment for superficial bladder cancer rarely causes pulmonary complications. While published cases have been pathologically characterized by multiple granulomatous lesions due
Mariko Itai, Mari Yamasue, Shuichi Takikawa, Kosaku Komiya, Yukiko Takeno, Yuriko Igarashi, Yasushi Takeshita, Kazufumi Hiramatsu, Satoshi Mitarai, Jun-ichi Kadota   +9 more
doaj   +1 more source

Trends in the incidence of Rifampicin resistant Mycobacterium tuberculosis infection in northeastern Nigeria

Scientific African, 2022
Mycobacterium tuberculosis is a respiratory bacterial pathogen that causes Tuberculosis. About one-quarter of the global population is infected, most of which are asymptomatic with a 5–15% risk of developing active disease across their lifespan.
Muhammad M. Ibrahim, Tom M. Isyaka, Umoru M. Askira, Jidda B. Umar, Mustafa A. Isa, Adam Mustapha, Akbar Salihu   +6 more
doaj   +1 more source

Prevalence of infection and rifampicin resistance among presumptive tuberculosis cases visiting tuberculosis clinic of Adare General Hospital, Southern Ethiopia

SAGE Open Medicine, 2021
Objective: Multidrug-resistant Mycobacterium tuberculosis is a public health threat in resource-limited countries where it is easily disseminated and difficult to control.
Degineh Belachew Andarge, Tariku Lambiyo Anticho, Getamesay Mulatu Jara, Musa Mohammed Ali   +3 more
doaj   +1 more source

Mycobacterium tuberculosis type VII secretion system effectors differentially impact the ESCRT endomembrane damage response [PDF]

, 2018
Mycobacterium tuberculosis causes tuberculosis, which kills more people than any other infection. M. tuberculosis grows in macrophages, cells that specialize in engulfing and degrading microorganisms.
Hanson, Phyllis I, Köster, Stefan, Mehra, Alka, Mittal, Ekansh, Philips, Jennifer A, Skowyra, Michael L, Tinaztepe, Emir, Uwase, Grace   +7 more
core   +2 more sources

An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]

, 2005
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS, Colston, MJ, Curry, JM, Gohil, K, Hunt, DM, Rickman, L, Smerdon, SJ, Strom, M, Whalan, R   +8 more
core   +2 more sources

Ultrasensitive enzyme-linked immunosorbent assay for the detection of MPT64 secretory antigen to evaluate Mycobacterium tuberculosis viability in sputum

International Journal of Infectious Diseases, 2020
Objectives: This study examined Mycobacterium tuberculosis (MTB)-secreted MPT64 as a surrogate of bacterial viability for the diagnosis of active pulmonary TB (PTB) and for follow-up treatment.
Kentaro Sakashita, Rikiya Takeuchi, Keita Takeda, Mikio Takamori, Kensuke Ito, Yuriko Igarashi, Eiji Hayashi, Mari Iguchi, Masahiro Ono, Tetsuya Kashiyama, Masatoshi Tachibana, Jun Miyakoshi, Koichi Yano, Yu Sato, Miyake Yamamoto, Kengo Murata, Akihiko Wada, Kinuyo Chikamatsu, Akio Aono, Akiko Takaki, Hideaki Nagai, Akira Yamane, Masahiro Kawashima, Mariko Komatsu, Kazunari Nakaishi, Satoshi Watabe, Satoshi Mitarai   +26 more
doaj   +1 more source

In vitro activities of contezolid (MRX-I) against drug-sensitive and drug-resistant Mycobacterium tuberculosis

Microbiology Spectrum, 2023
A novel oxazolidinone for the treatment of Mycobacterium tuberculosis has been developed, but the activity of contezolid (MRX-I) still needs to be clarified.
Huiru An, Wenna Sun, Xiao Liu, Tianhao Wang, Juan Qiao, Jianqin Liang   +5 more
doaj   +1 more source