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Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis
Mycobacterium tuberculosis is primarily a respiratory pathogen. However, 15% of infections worldwide occur at extrapulmonary sites causing additional complications for diagnosis and treatment of the disease. In addition, dissemination of M.
M. G. Moule, J. Cirillo
semanticscholar +1 more source
A recent study proposed the novel classification of the family Mycobacteriaceae based on the genome analysis of core proteins in 150 Mycobacterium species.
Hiroyuki Yamada+11 more
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A series of structome analyses, that is, quantitative and three-dimensional structural analysis of a whole cell at the electron microscopic level, have already been achieved individually in Exophiala dermatitidis, Saccharomyces cerevisiae, Mycobacterium ...
Hiroyuki Yamada+10 more
doaj +1 more source
Mechanisms of Drug-Induced Tolerance in Mycobacterium tuberculosis
Successful treatment of tuberculosis (TB) can be hampered by Mycobacterium tuberculosis populations that are temporarily able to survive antibiotic pressure in the absence of drug resistance-conferring mutations, a phenomenon termed drug tolerance.
Sander N. Goossens+2 more
semanticscholar +1 more source
Polymorphism in the EREG gene confers susceptibility to tuberculosis
Background Host genetic factors affect the immune response to Mycobacterium tuberculosis (Mtb) infection as well as the progression of the disease. Epiregulin (EREG) belongs to the epidermal growth factor (EGF) family, which binds to the epidermal growth
Wen Cao+7 more
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Background Intravesical instillation of bacillus Calmette–Guérin (BCG) as a treatment for superficial bladder cancer rarely causes pulmonary complications. While published cases have been pathologically characterized by multiple granulomatous lesions due
Mariko Itai+9 more
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The Roles of Host Noncoding RNAs in Mycobacterium tuberculosis Infection
Tuberculosis remains a major health problem. Mycobacterium tuberculosis, the causative agent of tuberculosis, can replicate and persist in host cells.
Li Wei+7 more
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Mycobacterium tuberculosis is a respiratory bacterial pathogen that causes Tuberculosis. About one-quarter of the global population is infected, most of which are asymptomatic with a 5–15% risk of developing active disease across their lifespan.
Muhammad M. Ibrahim+6 more
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DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams+117 more
core +1 more source
Immunity toMycobacterium tuberculosis [PDF]
Tuberculosis (TB) remains a major cause of mortality and morbidity worldwide. Currently, a third of the world's population is infected with Mycobacterium tuberculosis, the causative agent of TB, and annually there are 10 million new cases of clinical TB and approximately 2 million deaths [1]. TB kills more individuals each year than any other bacterial
Triccas, James A.+3 more
openaire +6 more sources