Diferenciação de micobactérias por PCR multiplex Differentiation of micobacteria by multiplex PCR
Revista da Sociedade Brasileira de Medicina Tropical, 2009 O trabalho visou à otimização de um método baseado na reação em cadeia da polimerase multiplex - para diferenciação de micobactérias de interesse para a saúde pública.
Diogo da Rocha Poroca +7 more
doaj +1 more source
Novel Antimicrobials from Uncultured Bacteria Acting against
mBio, 2020 Mycobacterium tuberculosis, which causes tuberculosis (TB), is estimated to infect one-third of the world’s population. The overall burden and the emergence of drug-resistant strains of Mycobacterium tuberculosis underscore the need for new therapeutic ...
Jeffrey Quigley +17 more
doaj +1 more source
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles’ heel for the TB-causing pathogen
FEMS Microbiology Reviews, 2019 Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis, remains one of the leading causes of mortality across the world. There is an urgent requirement to build a robust arsenal of effective antimicrobials, targeting novel ...
Arundhati Maitra +6 more
semanticscholar +1 more source
Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH.
, 2009 OBJECTIVES: The aim of this study was to gain an insight into the molecular mechanisms of the evolution of rifampicin resistance in response to controlled changes in the environment.
Allnutt, Jon +8 more
core +1 more source
Lipoproteins of Mycobacterium tuberculosis : an abundant and functionally diverse class of cell envelope components [PDF]
, 2004 Mycobacterium tuberculosis remains the predominant bacterial scourge of mankind. Understanding of its biology and pathogenicity has been greatly advanced by the determination of whole genome sequences for this organism.
Harrington, Dean, Sutcliffe, Iain
core +1 more source
In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]
, 2008 Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD +3 more
core +1 more source
Mycobacterium tuberculosis Metabolism [PDF]
Cold Spring Harbor Perspectives in Medicine, 2014 Metabolism underpins the physiology and pathogenesis of Mycobacterium tuberculosis. However, although experimental mycobacteriology has provided key insights into the metabolic pathways that are essential for survival and pathogenesis, determining the metabolic status of bacilli during different stages of infection and in different cellular ...
openaire +2 more sources
Innate Immunity toMycobacterium tuberculosis [PDF]
Clinical Microbiology Reviews, 2002 SUMMARYThe different manifestations of infection with Mycobacterium tuberculosis reflect the balance between the bacillus and host defense mechanisms. Traditionally, protective immunity to tuberculosis has been ascribed to T-cell-mediated immunity, with CD4+T cells playing a crucial role.
Crevel, R. van +2 more
openaire +10 more sources
Antimicrobial effects of folk medicinal plants from the North of Iran against Mycobacterium tuberculosis [PDF]
, 2015 Background: Medicinal plants have been used traditionally in Golestan province (north of Iran), against Mycobacterium tuberculosis or the clinical signs of tuberculosis (TB).
Davoodi, H. +6 more
core
Biofilms and Mycobacterium tuberculosis [PDF]
Infection and Immunity, 2017 There is good evidence that Mycobacterium tuberculosis evolved with Homo sapiens and, like our ancestors, migrated throughout the rest of the world from Africa some 70,000 years ago ([1][1]). Since M.
openaire +2 more sources