Results 81 to 90 of about 833,621 (293)
Mycobacterium tuberculosis is a respiratory bacterial pathogen that causes Tuberculosis. About one-quarter of the global population is infected, most of which are asymptomatic with a 5–15% risk of developing active disease across their lifespan.
Muhammad M. Ibrahim+6 more
doaj
A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains. [PDF]
In mycobacteria, CycA a D-serine, L- and D-alanine, and glycine transporter also functions in the uptake of D-cycloserine, an important second-line anti-tubercular drug. A single nucleotide polymorphism identified in the cycA gene of BCG was hypothesized
Jeffrey M Chen+3 more
doaj +1 more source
The species within the Mycobacterium tuberculosis Complex (MTBC) have undergone numerous taxonomic and nomenclatural changes, leaving the true structure of the MTBC in doubt. We used next-generation sequencing (NGS), digital DNA-DNA hybridization (dDDH),
Marco A. Riojas+4 more
semanticscholar +1 more source
Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum [PDF]
As nonreplicating tubercle bacilli are tolerant to the cidal action of antibiotics and resistant to multiple stresses, identification of this persister-like population of tubercle bacilli in sputum presents exciting and tractable new opportunities to ...
Alvarez+77 more
core +4 more sources
Mycobacterium tuberculosis phagosome [PDF]
The arrest of Mycobacterium tuberculosis phagosome maturation in infected macrophages is a phenomenon of dual significance both for the pathogenesis of tuberculosis and as a model system to study interference of microbes with membrane trafficking and organelle biogenesis in host cells.
Deretic, Vojo, Fratti, R. A.
openaire +4 more sources
Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human Diseases
Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely successful pathogen that adapts to survive within the host. During the latency phase of infection, M.
Qiyao Chai, Yong Zhang, C. Liu
semanticscholar +1 more source
POPULATION: Spinal cord injury (SCI) patients with neurogenic bladder have an increased risk for symptomatic urinary tract infection (UTI). Recurrent UTI requires multiple courses of antibiotic therapy, markedly increasing the incidence of multidrug ...
Bernard, Louis+6 more
core +1 more source
A re-evaluation of M. prototuberculosis [PDF]
It has been suggested that a group of smooth tubercle bacilli, isolated from patients with tuberculosis and associated with Djibouti, East Africa, along with the seven species and subspecies that are traditional members of the Mycobacterium tuberculosis ...
Marianne Manchester, Noel H Smith
core +3 more sources
Mycobacterium tuberculosis [PDF]
David W. Haas+2 more
openaire +5 more sources
Objectives: This study examined Mycobacterium tuberculosis (MTB)-secreted MPT64 as a surrogate of bacterial viability for the diagnosis of active pulmonary TB (PTB) and for follow-up treatment.
Kentaro Sakashita+26 more
doaj