Results 81 to 90 of about 833,621 (293)

Trends in the incidence of Rifampicin resistant Mycobacterium tuberculosis infection in northeastern Nigeria

open access: yesScientific African, 2022
Mycobacterium tuberculosis is a respiratory bacterial pathogen that causes Tuberculosis. About one-quarter of the global population is infected, most of which are asymptomatic with a 5–15% risk of developing active disease across their lifespan.
Muhammad M. Ibrahim   +6 more
doaj  

A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains. [PDF]

open access: yesPLoS ONE, 2012
In mycobacteria, CycA a D-serine, L- and D-alanine, and glycine transporter also functions in the uptake of D-cycloserine, an important second-line anti-tubercular drug. A single nucleotide polymorphism identified in the cycA gene of BCG was hypothesized
Jeffrey M Chen   +3 more
doaj   +1 more source

Phylogenomic analysis of the species of the Mycobacterium tuberculosis complex demonstrates that Mycobacterium africanum, Mycobacterium bovis, Mycobacterium caprae, Mycobacterium microti and Mycobacterium pinnipedii are later heterotypic synonyms of Mycobacterium tuberculosis.

open access: yesInternational Journal of Systematic and Evolutionary Microbiology, 2018
The species within the Mycobacterium tuberculosis Complex (MTBC) have undergone numerous taxonomic and nomenclatural changes, leaving the true structure of the MTBC in doubt. We used next-generation sequencing (NGS), digital DNA-DNA hybridization (dDDH),
Marco A. Riojas   +4 more
semanticscholar   +1 more source

Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum [PDF]

open access: yes, 2008
As nonreplicating tubercle bacilli are tolerant to the cidal action of antibiotics and resistant to multiple stresses, identification of this persister-like population of tubercle bacilli in sputum presents exciting and tractable new opportunities to ...
Alvarez   +77 more
core   +4 more sources

Mycobacterium tuberculosis phagosome [PDF]

open access: yesMolecular Microbiology, 1999
The arrest of Mycobacterium tuberculosis phagosome maturation in infected macrophages is a phenomenon of dual significance both for the pathogenesis of tuberculosis and as a model system to study interference of microbes with membrane trafficking and organelle biogenesis in host cells.
Deretic, Vojo, Fratti, R. A.
openaire   +4 more sources

Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human Diseases

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely successful pathogen that adapts to survive within the host. During the latency phase of infection, M.
Qiyao Chai, Yong Zhang, C. Liu
semanticscholar   +1 more source

Prevention of urinary tract infection in spinal cord-injured patients: safety and efficacy of a weekly oral cyclic antibiotic (WOCA) programme with a 2 year follow-up--an observational prospective study.

open access: yes, 2006
POPULATION: Spinal cord injury (SCI) patients with neurogenic bladder have an increased risk for symptomatic urinary tract infection (UTI). Recurrent UTI requires multiple courses of antibiotic therapy, markedly increasing the incidence of multidrug ...
Bernard, Louis   +6 more
core   +1 more source

A re-evaluation of M. prototuberculosis [PDF]

open access: yes, 2006
It has been suggested that a group of smooth tubercle bacilli, isolated from patients with tuberculosis and associated with Djibouti, East Africa, along with the seven species and subspecies that are traditional members of the Mycobacterium tuberculosis ...
Marianne Manchester, Noel H Smith
core   +3 more sources

Mycobacterium tuberculosis [PDF]

open access: yesRevista chilena de infectología, 2010
David W. Haas   +2 more
openaire   +5 more sources

Ultrasensitive enzyme-linked immunosorbent assay for the detection of MPT64 secretory antigen to evaluate Mycobacterium tuberculosis viability in sputum

open access: yesInternational Journal of Infectious Diseases, 2020
Objectives: This study examined Mycobacterium tuberculosis (MTB)-secreted MPT64 as a surrogate of bacterial viability for the diagnosis of active pulmonary TB (PTB) and for follow-up treatment.
Kentaro Sakashita   +26 more
doaj  

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