Results 111 to 120 of about 141,079 (249)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

MYCOPLASMA INFECTION

Journal of the Japanese Association for Infectious Diseases, 1970
openaire   +4 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Mycoplasma pneumoniae: gone forever?

The Lancet Microbe, 2023
Meyer Sauteur, Patrick M., Beeton, Michael L., Pereyre, Sabine, Bébéar, Cécile, Gardette, Marie, Hénin, Nadège, Wagner, Noémie, Fischer, Adrien, Vitale, Alessandra, Kessler, Julie, Andreutti, Corinne, Greub, Gilbert, Zimmermann, Petra, Agyeman, Philipp K.A., Aebi, Christoph, Buettcher, Michael, Hostettler, Marisa, Kottanattu, Lisa, Gaia, Valeria, Imkamp, Frank, Egli, Adrian, Berger, Christoph, Sidorov, Semjon, Tilen, Romy, Niederer-Loher, Anita, Barbey, Florence, Heininger, Ulrich, Ivan, Branislav, Papan, Cihan, Becker, Sören L., Forster, Johannes, Kohns Vasconcelos, Malte, Henrich, Birgit, MacKenzie, Colin R., Bossuyt, Nathalie, Vermeulen, Melissa, Matheeussen, Veerle, van Westreenen, Mireille, Verkaik, Nelianne J., Vogel, Marius, van Rossum, Annemarie M.C., Afshar, Baharak, Uldum, Søren Anker, Emborg, Hanne-Dorthe, Gullsby, Karolina, Laine, Miia, Peltola, Ville, Heinonen, Santtu, Døllner, Henrik, Width, Frode Gran, Christensen, Andreas, Buonsenso, Danilo, Rodrigues, Fernanda M.P., Rodrigues, Jorge, Tsantila, Katerina, Matsas, Minos, Kalogera, Eleni, Petridou, Evangelia, Kopsidas, Ioannis, Keše, Darja, Nir-Paz, Ran, Elinav, Hila, Michael-Gayego, Ayelet, Oishi, Tomohiro, Saraya, Takeshi, Hsieh, Yu-Chia, Wu, Tsung Hua, Maiwald, Matthias, Loo, Liat Hui, Sagar, Tanu, Chaudhry, Rama, Kociolek, Larry K., Rodríguez, Nadia, Lorenz, David, Blakiston, Matthew R.   +74 more
openaire   +3 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Clinical characteristics of community acquired pneumonia due to <i>Mycoplasma pneumoniae:</i> experience from an outbreak. [PDF]

Infez Med
Nair AA, Niyas VKM, Ananthanarayanan R, Durai SC, Jose D, Padmanabhan A.   +5 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Molecular detection of Mollicutes agents in reproductive system of cattle: a three-year study in Rio Grande do Sul, southern Brazil (2022-2024). [PDF]

Trop Anim Health Prod
Wessely HCA, Dotto EK, Costa ASMD, Vogel FSF, Cargnelutti JF, Antoniazzi AQ.   +5 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source