Results 221 to 230 of about 76,910 (294)

Downregulation of Lgals3 Alleviates Inflammatory Response and Apoptosis in a Mouse Model of Cerebral Ischemia/Reperfusion Injury. [PDF]

Brain Behav
Gan Z, Lai H, Yang Y, Lu J, Zhang W, Xiao J, Xu G.   +6 more
europepmc   +1 more source

Sinensetin From Citrus Peel Alleviates LPS‐Induced Acute Pneumonia by Regulating HIF‐1α Signaling Pathway in Mice

eFood, Volume 7, Issue 5, October 2026.
In this study, we found that sinensetin can effectively inhibit the inflammatory response and damage of lung cells caused by LPS in vivo and in vitro. This might be caused by the action of sinensetin in regulating the HIF‐1α‐MAPK signaling cascade.
Zuomin Hu, Yuchi Wu, Feijun Luo, Zhongxing Chu, Yongpan Huang, Jiali Ren, Zhengwen Li, Dandan Qin, Yiping Tang, Yaping Zhou   +9 more
wiley   +1 more source

Identification MYD88 as a candidate molecule of sodium overload-induced cell death in myocardial ischemia-reperfusion injury. [PDF]

J Cardiothorac Surg
Wang X, Zou C, He X, Liu S, Liu J.
europepmc   +1 more source

Pancreatic Cancer Disrupts Circadian Patterns of Gene Expression in Cardiorespiratory Muscles

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Cancer cachexia, a debilitating syndrome characterized by muscle wasting, significantly impacts survival in gastrointestinal cancers like pancreatic cancer. Emerging evidence suggests a link between cancer cachexia and disrupted circadian rhythms in peripheral tissues, including locomotor muscles. However, circadian dysregulation in
Jeremy B. Ducharme, Martin M. Schonk, Miguel A. Gutierrez‐Monreal, Leonardo F. Ferreira, Karyn A. Esser, Andrew R. Judge, Sarah M. Judge   +6 more
wiley   +1 more source

Baihe Dihuang decoction activates cannabinoid type 2 receptor to regulate microglial polarization and alleviate anxiety-like behavior in chronic restraint stress mice. [PDF]

J Tradit Chin Med
Qiaoyun L, Yuanshan H, Yang L, Lin T, Tianyu W, Yuhong W, Hongqing Z.   +6 more
europepmc   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 10, Page 2072-2084, October 2026.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass, Simon Swift, Saeid Baroutian   +2 more
wiley   +1 more source

Context-dependent effects of microglial MyD88 removal on voluntary ethanol consumption in mice. [PDF]

Neuropharmacology
Dziabis JE, Rogers N, Horvath BL, Patton MS, Jonathan IO, Freeman EJ, Sun W, Moulden J, Zhang G, Bilbo SD.   +9 more
europepmc   +1 more source

Gastrointestinal Microbiome Dysbiosis in Cancer Development: Mechanisms and Biomarker Potential

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Dysbiosis of the gastrointestinal microbiome plays a role in carcinogenesis by inducing chronic inflammation, DNA damage, and activation of signaling pathways such as NF‐κB, STAT3, and Wnt/β‐catenin. Microorganisms such as Helicobacter pylori, Fusobacterium nucleatum, and Bacteroides fragilis promote the development of gastrointestinal tumors through ...
Negar Asgari, Mehrasa Asghari, Touraj Farazmandfar   +2 more
wiley   +1 more source

Engineered microvesicle-mediated multimodal therapy resolves ulcerative colitis via synergistic immunoregulation, barrier restoration, and microbiota remodeling. [PDF]

Mater Today Bio
Qi C, Liang C, Wang S, Zhang H, Wei H, He X, Chen W.   +6 more
europepmc   +1 more source

Osteomyelitis: Epidemiology, Classification, Pathophysiology, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
The immunosuppressive in OM Staphylococcus aureus employs multiple physical barriers to evade host immunity during skeletal infection, including biofilm formation on implant surfaces and necrotic bone tissues, invasion into the osteocyte lacuno‐canalicular network (OLCN), intracellular persistence within osteoblasts, osteoclasts, and osteocytes, and ...
Qingqiang Lei, Liangbin Lin, Peidong Pu, Jie Chen, Xianchao Su, Shubao Liu, Yanli Tong, Hui Yu   +7 more
wiley   +1 more source