Results 51 to 60 of about 184,937 (258)

Proteasome Biology Is Compromised in White Matter After Asphyxic Cardiac Arrest in Neonatal Piglets

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Neurological deficits in hypoxic‐ischemic encephalopathy, even with therapeutic hypothermia, are partially attributed to white matter injury. We theorized that proteasome insufficiency contributes to white matter injury.
Polan T. Santos, Caitlin E. O'Brien, May W. Chen, C. Danielle Hopkins, Shawn Adams, Ewa Kulikowicz, Rashmi Singh, Raymond C. Koehler, Lee J. Martin, Jennifer K. Lee   +9 more
doaj   +1 more source

Myelin Oligodendrocyte Glycoprotein-Immunoglobulin G in the CSF

Neurology: Neuroimmunology & Neuroinflammation, 2021
Background and Objective To investigate the clinical relevance of CSF myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) testing in a large multicenter cohort.
Y. Kwon, Boram Kim, Jun-Soon Kim, Hee-Hung Mo, Kyomin Choi, Seong-il Oh, Jee-Eun Kim, T. Nam, E. Sohn, S. Heo, Sang Beom Kim, Key-Chung Park, S. Yoon, Jeeyoung Oh, S. Baek, B. Kim, Kyung Seok Park, Jung-Joon Sung, Jae Ho Jung, Seong-Joon Kim, Sung-Hye Park, P. Waters, Sung-Min Kim   +22 more
semanticscholar   +1 more source

The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody

Acta Neuropathologica, 2020
We sought to define the pathological features of myelin oligodendrocyte glycoprotein (MOG) antibody associated disorders (MOGAD) in an archival autopsy/biopsy cohort.
R. Höftberger, Yong Guo, E. Flanagan, A. Lopez-Chiriboga, V. Endmayr, S. Hochmeister, Damir Joldic, Sean J. Pittock, J. Tillema, M. Gorman, H. Lassmann, C. Lucchinetti   +11 more
semanticscholar   +1 more source

Acute symptomatic seizures secondary to Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

Epilepsia, 2022
To report the clinical presentations and outcomes of patients with seizure and myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD).
Mayra Montalvo, Jamal F. Khattak, Vyanka Redenbaugh, J. Britton, Cristina Valencia Sanchez, Abhigyan Datta, J. Tillema, John Chen, A. McKeon, S. Pittock, E. Flanagan, D. Dubey   +11 more
semanticscholar   +1 more source

SARS‐COV‐2 a trigger of myelin oligodendrocyte glycoprotein‐associated disorder

Annals of Clinical and Translational Neurology, 2022
SARS‐COV‐2 frequently cause neurological disorders and is sometimes associated with onset of autoimmune diseases affecting the nervous system. Over recent years, a rare but distinct diagnosis designated myelin oligodendrocyte glycoprotein‐associated ...
Magnus Johnsson, F. Asztely, Susanne Hejnebo, M. Axelsson, C. Malmeström, T. Olausson, J. Lycke   +6 more
semanticscholar   +1 more source

Particular aspects of myelin-axon interactions in health and disease : the expression of myelin-associated glycoprotein isoforms in CNS and PNS. Early axonal pathology in the dysmyelinating peripheral neuropathy CMT1A [PDF]

, 2007
An intact myelin sheath is crucial for the rapid propagation of action potentials along myelinated axons. There are many neurodegenerative diseases associated with defect myelin sheaths resulting in severe clinical symptoms such as multiple sclerosis ...
Flück, Bettina
core   +1 more source

Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal

Case Reports in Neurological Medicine, 2021
Neuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis.
Sangam Shah, Rajeev Ojha, Sanjeeta Sitaula, Dosti Regmi, Ragesh Karn, Bikram Prasad Gajurel, Reema Rajbhandari, Niraj Gautam, Sunanda Paudel, Aashish Shrestha   +9 more
doaj   +1 more source

Distinct serum and cerebrospinal fluid cytokine and chemokine profiles in autoantibody-associated demyelinating diseases

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2019
Background Demyelinating diseases of the central nervous system associated with autoantibodies against aquaporin-4 and myelin-oligodendrocyte-glycoprotein are mediated by different immunopathological mechanisms compared to multiple sclerosis.
Livia S Hofer, Sara Mariotto, Sebastian Wurth, Sergio Ferrari, Chiara R Mancinelli, Rachele Delogu, Salvatore Monaco, Alberto Gajofatto, Carmen Schwaiger, Kevin Rostasy, Florian Deisenhammer, Romana Höftberger, Thomas Berger, Markus Reindl   +13 more
doaj   +1 more source

The AD946 antibody recognizes a 6xHis-tagged recombinant protein by Western blot

Antibody Reports, 2018
The recombinant antibody AD946 detects by Western blot the 6xHis-tagged human myelin oligodendrocyte glycoprotein (MOG).
Otmane Lamrabet, Tania Jauslin
doaj   +1 more source

Frequency of myelin oligodendrocyte glycoprotein antibodies in a large cohort of neurological patients

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2021
Background Myelin oligodendrocyte glycoprotein (MOG) antibody disease (MOG-AD) is recognized as a distinct nosological entity. IgG antibodies against MOG (MOG-Ab) overlap with neuromyelitis optica spectrum disorders (NMOSD) phenotype in adults.
Friederike Held, S. Kalluri, A. Berthele, Ana-Katharina Klein, M. Reindl, B. Hemmer   +5 more
semanticscholar   +1 more source