Results 121 to 130 of about 96,245 (184)

ILAE neuroimaging task force highlight: MRI detection of early life epilepsy caused by focal cortical dysplasia

open access: yesEpileptic Disorders, EarlyView.
Abstract The ILAE Neuroimaging Task Force aims to publish educational case reports that highlight basic aspects of neuroimaging in epilepsy consistent with the ILAE's educational mission. Here, we describe a case series of three neonates with focal cortical dysplasia (FCD)‐related drug‐resistant epilepsy who underwent surgical intervention. The purpose
Nathan T. Cohen   +18 more
wiley   +1 more source

A pilot study on the programming protocol of vagus nerve stimulation in children with drug‐resistant epilepsy: High pulse amplitude or high duty cycle

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To compare the efficacy and safety of vagus nerve stimulation using different modes in patients with drug‐resistant epilepsy (DRE). Methods Children with DRE who underwent vagus nerve stimulator implantation between March 2019 and December 2022 were prospectively enrolled at the Peking University First Hospital.
Yuying Pan   +9 more
wiley   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

open access: yesExploration, EarlyView.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du   +7 more
wiley   +1 more source

Dual‐Responsive Multi‐Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury

open access: yesExploration, EarlyView.
Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby ...
Guibin Gao   +12 more
wiley   +1 more source

The Metabolism of Myelin [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1961
openaire   +3 more sources

Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang   +3 more
wiley   +1 more source

Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting‐Edge Antioxidants

open access: yesGlobal Challenges, EarlyView.
This review has systematically evaluated the oxidative damage of cornea, tear film, lacrimal gland, conjunctiva and meibomian gland for dry eye, and concluded the antioxidants that are either commercially available or in the research phase. GQDs: Graphene quantum dots; LF: lactoferrin; ROS: Reactive oxygen species; SOD: Superoxide dismutase; tFNA ...
Rong Hu   +3 more
wiley   +1 more source

Myelin Formation by Oligodendrocytes Is Enhanced Through Laminin‐411 and Its Derived Peptide

open access: yesGlia, EarlyView.
Laminin (LM) α1, α2, and α4 chains are expressed at the myelination stage of oligodendrocyte (OL). LM411 and its E8 fragment enhance OL myelin membrane formation. A4G47 from LM411E8 is a novel peptide that promotes OL myelin formation. ABSTRACT In the central nervous system, oligodendrocytes (OLs) form myelin sheaths that accomplish the efficient ...
Binri Sasaki   +14 more
wiley   +1 more source

Microglial IKKβ Alters Central and Peripheral Immune Activity at Distinct Time Points After Spinal Cord Injury

open access: yesGlia, EarlyView.
Microglial NF‐κB signaling increases M1‐like spinal microglia over time after spinal cord injury. Microglial NF‐κB signaling broadly affects gene expression in spinal cord. Microglial NF‐κB signaling modulates splenocytes acutely after spinal cord injury.
Micaela L. O'Reilly   +8 more
wiley   +1 more source

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