Results 201 to 210 of about 188,742 (365)

Regional Cerebral Atrophy Contributes to Personalized Survival Prediction in Amyotrophic Lateral Sclerosis: A Multicentre, Machine Learning, Deformation‐Based Morphometry Study

open access: yesAnnals of Neurology, EarlyView.
Objective Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve individual survival predictions.
Isabelle Lajoie   +3 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä   +18 more
wiley   +1 more source

Molecular testing of soft tissue tumors

open access: yesDiagnostic Cytopathology, Volume 51, Issue 1, Page 12-25, January 2023., 2023
Abstract Background The diagnosis of soft tissue tumors is challenging, especially when the evaluable material procured is limited. As a result, diagnostic ancillary testing is frequently needed. Moreover, there is a trend in soft tissue pathology toward increasing use of molecular results for tumor classification and prognostication. Hence, diagnosing
Douglas Rottmann   +2 more
wiley   +1 more source

Predator–Prey Behavior of Droplets Propelling Through Self‐Generated Channels in Crystalline Surfactant Layers

open access: yesAngewandte Chemie, EarlyView.
A crystalline layer is formed by an amphiphilic decylamine surfactant at the air/water interface. Aldehyde‐containing ester oil droplets self‐propel by consuming amines from the crystalline layer, thereby generating open channels along which myelin‐forming amphiphile droplets chase and ultimately catch the aldehyde droplets in a predator–prey analogy ...
Priyanshu Singh, Peter A. Korevaar
wiley   +2 more sources

Signs of Cortical Inflammation in Migraine Measured with Quantitative Magnetic Resonance Imaging: A Registry for Migraine (REFORM) Study

open access: yesAnnals of Neurology, EarlyView.
Objective The involvement of cortical inflammation in migraine, particularly migraine with aura, has been a subject of considerable interest, but has proved challenging to demonstrate. We aimed to detect and characterize signs of cortical inflammation in adults with migraine using a novel, multimodal magnetic resonance imaging (MRI) technique.
Rune H. Christensen   +8 more
wiley   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek   +18 more
wiley   +1 more source

Imaging Heterogeneous Patterns of Aminopeptidase N Activity in Hierarchical Tissue Structures Through High‐Resolution Whole‐Organ 3D Mapping

open access: yesAngewandte Chemie, EarlyView.
Enzymes regulate physiological functions, and their abnormal activity is associated with diseases. Here, we present a method for high‐resolution 3D mapping of enzyme activity using tissue clearing and an activity‐based covalent probe. Focusing on aminopeptidase N, we developed ANA‐o‐BODIPY, which records enzyme activity via covalent labeling.
Bo Yi   +10 more
wiley   +2 more sources

Editorial: Recent Advances in Myelin Plasticity

open access: yesFrontiers in Cellular Neuroscience, 2021
Domna Karagogeos   +4 more
doaj   +1 more source

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