Glia, EarlyView.ABSTRACT Spinal cord injury (SCI) results in significant disruption of nerve fibers responsible for transmitting signals between the brain and body, often leading to partial or complete motor, sensory, and autonomic dysfunction below the injury site. Astrocytes are an important component in scar formation, crucial for suppression of injury propagation,
Barbora Smejkalová +12 more
wiley +1 more source
Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor Vβ-specific antibodies [PDF]
, 1990 Experimental allergic encephalomyelitis (EAE) is a model system for T cell-mediated autoimmune disease. Symptoms of EAE are similar to those of multiple sclerosis (MS) in humans.
Hood, Leroy +3 more
core
Localization of sites for ionic interaction with lipid in the C-terminal third of the bovine myelin basic protein [PDF]
, 1977 Andrew J. S. Jones, Martin G. Rumsby
openalex +1 more source
A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis
Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo +7 more
wiley +1 more source
Myelin basic proteins in myelin subfractions from normal and quaking mice [PDF]
, 1979 Graham E. Fagg, Thomas V. Waehneldt
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Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
Morphological study of Schwann cells remyelination in contused spinal cord of rats
Chinese Journal of Traumatology, 2013 【Abstract】Objective: To study the role and effect of Schwann cells (SCs) remyelination in contused spinal cord. Methods: Green fluorescence protein expressing-SCs were transplanted into the epicenter, rostral and caudal tis-sues of the injury ...
LI Yue +5 more
doaj
Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo. [PDF]
, 2019 In this study, we have developed highly expandable neural stem cells (NSCs) from HESCs and iPSCs that artificially express the oligodendrocyte (OL) specific transcription factor gene Zfp488. This is enough to restrict them to an exclusive oligodendrocyte
Biswas, Sangita +4 more
core +1 more source
Research progress of neurovascular units involved in ischemic stroke
Ibrain, EarlyView.The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang +4 more
wiley +1 more source
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2019 Introduction: Multiple sclerosis (MS) is a common neurodegenerative disease leading to the movement disorder and destruction of myelin. Physical exercise delays the onset of neurodegenerative processes by preventing the destruction of myelin and ...
Maryam Naghibzadeh +3 more
doaj +2 more sources