Results 251 to 260 of about 212,147 (360)
ABSTRACT Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease. While typically diagnosed in young adults, late‐onset MS (LOMS, onset > 50 years) is becoming increasingly recognized, presenting with distinct features such as higher rates of progressive onset and motor symptoms.
Takuya Matsushita
wiley +1 more source
Ibogaine administration following repeated morphine administration upregulates myelination markers 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) and myelin basic protein (MBP) mRNA and protein expression in the internal capsule of Sprague Dawley rats. [PDF]
Govender D+5 more
europepmc +1 more source
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin+4 more
wiley +1 more source
Normal immunoglobulin G protects against experimental allergic encephalomyelitis by inducing transferable T cell unresponsiveness to myelin basic protein [PDF]
Anastas Pashov+6 more
openalex +1 more source
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley +1 more source
Association of JC Virus Large T Antigen with Myelin Basic Protein Transcription Factor (MEF-1/Purα) in Hypomyelinated Brains of Mice Transgenically Expressing T Antigen [PDF]
Anna Tretiakova+6 more
openalex +1 more source
Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk
This graphical abstract illustrates the reciprocal crosstalk between the brain and peripheral organs, highlighting the profound impact of exercise on brain health through systemic interactions. It underscores how exercise influences the brain via signals from various organs and, conversely, how the brain modulates functions of peripheral organs.
Shirin Pourteymour+3 more
wiley +1 more source