Results 281 to 290 of about 90,594 (330)

The distribution of myelin basic protein mRNAs within myelinating oligodendrocytes

Trends in Neurosciences, 1993
The nervous system contains oligodendrocytes with processes that are greatly extended in space. It is now clear that there are numerous complex, poorly understood mechanisms by which polypeptides are synthesized and delivered to their sites of function in these cells.
P J, Brophy, G L, Boccaccio, D R, Colman
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Myelin basic protein and multiple sclerosis

The Italian Journal of Neurological Sciences, 1983
Myelin basic protein (BP) has the capacity to induce experimental allergic encephalomyelitis (EAE) in animals as well as to prevent and suppress EAE. Immunoreactive BP or BP fragments appear in cerebrospinal fluid (CSF) in persons with multiple sclerosis in acute disease periods and in individuals with acute damage to central nervous system myelin ...
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MYELIN BASIC PROTEIN MICROHETEROGENEITY IN SUBFRACTIONS OF RAT BRAIN MYELIN

Journal of Neurochemistry, 1978
Abstract— Myelin subfractions were prepared from adult rat brain by discontinuous sucrose gradient ultracentrifugation. Gel electrophoretic studies at pH 10.6 in the presence of urea revealed differences in basic protein microheterogeneity among subfractions.
C W, Shults, J N, Whitaker, J G, Wood
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Phosphorylation on basic amino acids in myelin basic protein

Biochemical and Biophysical Research Communications, 1976
Abstract Isolated rat brain myelin when incubated with γ 32 P labelled ATP yields proteins bearing acid labile, base stable phosphoryl groups. Phosphorylated myelin basic protein can be isolated and degraded with trypsin and pronase to yield principally phosphoarginine and phosphohistidine.
L S, Smith, C W, Kern, R M, Halpern, R A, Smith   +3 more
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Encephalitogenic Epitopes of Myelin Basic Protein

1989
Etude des determinants antigeniques de la proteine basique myeline capable d'induire une encephalomyelite allergique.
R B, Fritz, D E, McFarlin
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Nuclear transport of myelin basic protein

Journal of Neuroscience Research, 1997
The multiple myelin basic protein (MBP) isoforms expressed by myelinating cells are now known to have different expression patterns. The relative abundance of the isoforms containing exon II is greater early in myelinogenesis, whereas in compact myelin the isoforms lacking this exon are more abundant.
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Myelin Basic Protein and Demyelinating Diseases

CRC Critical Reviews in Clinical Laboratory Sciences, 1986
Myelin basic protein (MBP) is a major protein component of myelin sheath. Primarily because of its ability to induce experimental allergic encephalomyelitis (EAE) in animals, this protein has been considered to play an important role in the pathogenesis of multiple sclerosis (MS), which is one of the most common demyelinating diseases.
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From Myelin Basic Protein to Myelin Deficient Mice

1990
In order to control diseases affecting myelination, an understanding of normal myelin structure and its formation is essential. Paradoxically, much information about normal development can be obtained through investigations of hypomyelinated mutants.
M. Tosic, J.-M. Matthieu
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Myelin basic protein

Biochemical Society Transactions, 1980
M G, Rumsby, A G, Walker
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Isolation of Myelin Basic Proteins

1974
The history of basic protein in myelin from the central nervous system (CNS) is closely involved with the laboratory disease known as experimental allergic encephalomyelitis (EAE; Alvord, 1970). EAE was shown to be an autoimmune disease when Rabat et al.
Peter R. Dunkley, Patrick R. Carnegie
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