Results 141 to 150 of about 130,050 (381)
Advanced Science, EarlyView.How locus coeruleus noradrenergic‐spinal projections and subsequent α2A adrenoceptors‐CaMKII signaling cascades contribute to electroacupuncture‐induced antinociception in postoperative pain in mice is described. Abstract Postoperative pain remains a significant challenge in healthcare.
Wen‐Guang Chu +13 more
wiley +1 more source
Intrinsic dynamical fluctuations of PNS myelin [PDF]
arXiv, 2017 The ultrastructure fluctuations and complex dynamics of the multi-layered membrane structure of myelin are fundamental for understanding and control its formation process and its degeneration and repair in neurological diseases such as multiple sclerosis (MS).
arxiv
Immunocytochemical localization studies of myelin basic protein. [PDF]
, 1978 Jerry R. Mendell, John N. Whitaker
openalex +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models
Journal of Lipid Research, 2011 The integrity of central and peripheral nervous system myelin is affected in numerous lipid metabolism disorders. This vulnerability was so far mostly attributed to the extraordinarily high level of lipid synthesis that is required for the formation of ...
Roman Chrast +3 more
doaj
The signal synchronization function of myelin [PDF]
arXivThe myelinated axons are widely present in both central and peripheral nervous systems. Its unique compact spiraling structure poses significant challenges to understanding its biological functions and developmental mechanisms. Conventionally, myelin is considered as an insulating layer to achieve saltatory conduction for the enhancement of the neural ...
arxiv
Cell vibron polariton in the myelin sheath of nerve [PDF]
arXiv, 2019 Polaritons are arousing tremendous interests in physics and material sciences for their unique and amazing properties, especially including the condensation, lasing without inversion and even room-temperature superfluidity. Herein, we propose a cell vibron polariton (cell-VP): a collectively coherent mode of a photon and all phospholipid molecules in a
arxiv
Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain
Advanced Science, EarlyView.Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang +9 more
wiley +1 more source
Oligodendrocytes express synaptic proteins that modulate myelin sheath formation
Nature Communications, 2019 Oligodendrocyte processes can detect and respond to axonal vesicular release. The authors here show in zebrafish that transsynaptic adhesion molecules, molecules that promote synapse formation and maturation in neurons, are expressed by oligodendrocytes ...
Alexandria N. Hughes, Bruce Appel
doaj +1 more source
Convolutional Neural Networks for Estimation of Myelin Maturation in Infant Brain [PDF]
arXiv, 2019 Myelination plays an important role in the neurological development of infant brain and MRI can visualize the myelination extension as T1 high and T2 low signal intensity at white matter. We tried to construct a convolutional neural network machine learning model to estimate the myelination. Eight layers CNN architecture was constructed to estimate the
arxiv