Results 181 to 190 of about 201,896 (346)

3-photon fluorescence and third-harmonic generation imaging of myelin sheaths in mouse digital skin in vivo: A comparative study

, 2021
Ke Wang, Yi Pan, Xinlin Chen, Shen Tong, Huiping Liang, Lu Yuan, Ping Qiu   +6 more
openalex   +1 more source

Myelin basic protein demonstrated immunocytochemically in oligodendroglia prior to myelin sheath formation.

, 1978
Nancy H. Sternberger, Yasuto Itoyama, M W Kies, H. deF. Webster   +3 more
openalex   +1 more source

Quantitative T1 is sensitive to cortical remyelination in multiple sclerosis: A postmortem MRI study

Brain Pathology, EarlyView.
In a post‐mortem study using multiparametric qMRI of whole fixed human brains from people with multiple sclerosis (pwMS), we found evidence that quantitative T1 (qT1) is sensitive to remyelination in the cortex. In contrast, QSM and radial diffusivity were affected by cortical pathology independently of remyelination. Our data suggest that qT1 could be
Riccardo Galbusera, Matthias Weigel, Erik Bahn, Sabine Schaedelin, Alessandro Cagol, Po‐Jui Lu, Muhamed Barakovic, Lester Melie‐Garcia, Jonas Franz, Peter Dechent, Govind Nair, Ludwig Kappos, Wolfgang Brück, Christine Stadelmann, Cristina Granziera   +14 more
wiley   +1 more source

Nonvesicular lipid transfer drives myelin growth in the central nervous system

Nature Communications
Oligodendrocytes extend numerous cellular processes that wrap multiple times around axons to generate lipid-rich myelin sheaths. Myelin biogenesis requires an enormously productive biosynthetic machinery for generating and delivering these large amounts ...
Jianping Wu, Georg Kislinger, Jerome Duschek, Ayşe Damla Durmaz, Benedikt Wefers, Ruoqing Feng, Karsten Nalbach, Wolfgang Wurst, Christian Behrends, Martina Schifferer, Mikael Simons   +10 more
doaj   +1 more source

The Morphological Changes of Oligodendroglia During the Formation of Myelin Sheaths

, 1973
Yoshiro Inoue, Yoshihiro Sugihara, Shoji Nakagawa, Kazuyo Shimai   +3 more
openalex   +2 more sources

Regenerating Locus Coeruleus‐Norepinephrine (LC‐NE) Function: A Novel Approach for Neurodegenerative Diseases

Cell Proliferation, EarlyView.
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley   +1 more source

Proteomic Profiling of Cerebrum Mitochondria, Myelin Sheath, and Synaptosome Revealed Mitochondrial Damage and Synaptic Impairments in Association with 3 × Tg-AD Mice Model. [PDF]

Cell Mol Neurobiol, 2022
Shen L, Yang A, Chen X, Xiao S, Liu X, Lin J, Zhao Y, Zhang K, Li C, Ke J, Zhang H, Khan NU.   +11 more
europepmc   +1 more source

Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk

Cell Proliferation, EarlyView.
This graphical abstract illustrates the reciprocal crosstalk between the brain and peripheral organs, highlighting the profound impact of exercise on brain health through systemic interactions. It underscores how exercise influences the brain via signals from various organs and, conversely, how the brain modulates functions of peripheral organs.
Shirin Pourteymour, Rakesh Kumar Majhi, Frode A. Norheim, Christian A. Drevon   +3 more
wiley   +1 more source

Dysregulation of Myelination in Focal Cortical Dysplasia Type II of the Human Frontal Lobe. [PDF]

Glia
Main Points FCD IIa shows a normal radial myelin fiber pattern, thinner myelin sheaths and reduced myelin synthesis. FCD IIb has disorganized myelinated fibers, thicker myelin sheaths, more oligodendrocytes, and an increased transcription rate of myelin genes.
Donkels C, Häussler U, Huber S, Tiesmeyer N, Demerath T, Scheiwe C, Shah MJ, Heers M, Urbach H, Schulze-Bonhage A, Prinz M, Vlachos A, Beck J, Nakagawa JM, Haas CA.   +14 more
europepmc   +2 more sources

A reaction-diffusion model for relapsing-remitting multiple sclerosis with a treatment term [PDF]

arXiv
We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines, consumption of myelin sheath due to anomalously activated lymphocytes and its restoration by oligodendrocytes ...
arxiv