Results 181 to 190 of about 232,901 (341)

Erratum to: Anosmin-1 over-expression regulates oligodendrocyte precursor cell proliferation, migration and myelin sheath thickness [PDF]

, 2015
Verónica Murcia‐Belmonte, Pedro F. Esteban, José Martínez Hernández, Agnès Gruart, Rafael Luján, José M. Delgado‐García, Fernando de Castro   +6 more
openalex   +1 more source

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

Brain Pathology, EarlyView.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong, Weixing Yan, Qiqi Meng, Xueli Song, Bing Cheng, Yaping Liu, Yanan Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death. [PDF]

Cell Rep, 2022
Aber ER, Griffey CJ, Davies T, Li AM, Yang YJ, Croce KR, Goldman JE, Grutzendler J, Canman JC, Yamamoto A.   +9 more
europepmc   +1 more source

Synaptic ultrastructural alterations in human focal cortical dysplasia: Insights from volume electron microscopy

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim, Na‐Young Seo, Seung‐Ki Kim, Jae‐Kyung Won, Yang Hoon Huh, Ji Yeoun Lee, Kea Joo Lee   +6 more
wiley   +1 more source

Effect of 17β estradiol on hippocampus region of aging female rat brain: Ultrastructural study

American Journal of Experimental and Clinical Research, 2015
Estradiol has direct membrane-mediated effects on neurons and its effects are both neuroprotective and neurotrophic. This hormone modulates brain development and aging and affects neurochemical systems which are affected in age-related cognitive decline,
Rashmi Jha, Ranjeet Kumar, Priyanka Mishra, Abbas Ali Mahdi, Shivani Pandey, Najma Zaheer Baquer, Sudha Mahajan Cowsik   +6 more
doaj  

Olig2‐specific loss‐of‐function Slc35a2 results in hypomyelination and spontaneous seizures

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development represent major causes of drug‐resistant epilepsy, with mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy recognized as a distinct pathological entity. Pathogenic X‐linked SLC35A2, encoding the uridine diphosphate–galactose transporter, has been implicated ...
Tiffany M. Bartel, Chaitali Ghosh, Kathryn Bisaha, Jean Khoury, Ashley Nemes‐Baran, Ingmar Blumcke, Imad Najm   +6 more
wiley   +1 more source

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

Equine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan, J. Burns, E. John, M. Buote   +3 more
wiley   +1 more source

Cone beam computed tomographic myelography in horses with cervical vertebral compressive myelopathy

Equine Veterinary Journal, EarlyView.
Abstract Background While computed tomographic (CT) myelography is increasingly available and has been evaluated in alive horses, objective criteria for diagnosing cervical vertebral compressive myelopathy (CVCM) are lacking. Objectives To establish morphometric dimensions of the cervical vertebral canal and spinal cords from horses with CVCM and ...
Sonia González‐Medina, Myra F. Barrett, Tawfik A. Aboellail, Bradley B. Nelson, Yvette S. Nout‐Lomas   +4 more
wiley   +1 more source

FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult central nervous system

Nature Communications
Myelin, along with the oligodendrocytes (OLs) that produce it, is essential for proper central nervous system (CNS) function in vertebrates. Although the accurate targeting of myelin to axons and its maintenance are critical for CNS performance, the ...
Hannah Y. Collins, Ryan A. Doan, Jiaxing Li, Jason E. Early, Megan E. Madden, Tyrell Simkins, David A. Lyons, Kelly R. Monk, Ben Emery   +8 more
doaj   +1 more source

Regeneration of sensory nerve branches in extraction socket and surrounding alveolar bone in rat: immunohistochemical observation of the axon and myelin sheath changes. [PDF]

Odontology, 2023
Kakuta W, Matsunaga S, Otsu Y, Kitamura K, Abe S, Yajima Y, Sekine H.   +6 more
europepmc   +1 more source