Results 191 to 200 of about 48,603 (346)

Motor pathway evaluation by transcranial magnetic stimulation in Swedish horses with acquired equine polyneuropathy

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Acquired equine polyneuropathy in Nordic horses (AEP) is the most prevalent equine polyneuropathy in Norway, Sweden, and Finland and is characterised by pelvic limb knuckling due to metatarsophalangeal extension dysfunction.
Anna May   +6 more
wiley   +1 more source

The Morphological Changes of Oligodendroglia During the Formation of Myelin Sheaths

open access: bronze, 1973
Yoshiro Inoue   +3 more
openalex   +2 more sources

Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity

open access: yesThe FEBS Journal, EarlyView.
RANKL treatment induces expression of the aconitate decarboxylase (ACOD1) in differentiating osteoclasts, which increases succinate levels. The initially high expression of ACOD1 decreases towards the end of differentiation when the levels of the desuccinylase SIRT5 increase. Succinylation of citrate synthase (CS) was detected exclusively in stimulated
Dayoung Yu   +7 more
wiley   +1 more source

On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation

open access: yesThe FEBS Journal, EarlyView.
Myelin is a multilayered proteolipid membrane in the nervous system. The lipid membranes are held together by specific proteins, and here, we studied three such proteins—P0, MBP, and P2. Our experiments show that the three proteins may act in synergy at the molecular level, while they also compete for lipid membrane surface binding.
Oda C. Krokengen   +9 more
wiley   +1 more source

Nonvesicular lipid transfer drives myelin growth in the central nervous system

open access: yesNature Communications
Oligodendrocytes extend numerous cellular processes that wrap multiple times around axons to generate lipid-rich myelin sheaths. Myelin biogenesis requires an enormously productive biosynthetic machinery for generating and delivering these large amounts ...
Jianping Wu   +10 more
doaj   +1 more source

Sex‐dimorphic gene regulation in murine macrophages across niches

open access: yesImmunology &Cell Biology, EarlyView.
In this study, we perform a meta‐analysis of new and publicly available RNA‐seq datasets from male and female mouse macrophages across eight niches to identify conserved sex‐dimorphic gene expression patterns. We found that three sex chromosome‐linked genes are always differentially expressed between males and females: Ddx3y, Eif2s3y and Xist. However,
Cassandra J McGill   +4 more
wiley   +1 more source

Mind the GAPS: Glia associated with psychological stress

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Glial cells are an integral component of the nervous system, performing crucial functions that extend beyond structural support, including modulation of the immune system, tissue repair, and maintaining tissue homeostasis. Recent studies have highlighted the importance of glial cells as key mediators of stress responses across different organs.
Niklas Blank   +4 more
wiley   +1 more source

Topohistology of dendritic cells and macrophages in the distal and proximal nodes along the lymph flow from the lung

open access: yesJournal of Anatomy, EarlyView.
Proximal node (subcarinal node) from a patient with lower‐lobe lung cancer. The complementary distribution was seen between CD68‐positive macrophages and CD169‐positive cells, and the latter tended to exist with DCsign‐positive cells. The island‐like appearance of the cortex was seen in the nodes.
Masaya Aoki   +5 more
wiley   +1 more source

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