Results 191 to 200 of about 48,603 (346)
Abstract Background Acquired equine polyneuropathy in Nordic horses (AEP) is the most prevalent equine polyneuropathy in Norway, Sweden, and Finland and is characterised by pelvic limb knuckling due to metatarsophalangeal extension dysfunction.
Anna May+6 more
wiley +1 more source
The Morphological Changes of Oligodendroglia During the Formation of Myelin Sheaths
Yoshiro Inoue+3 more
openalex +2 more sources
RANKL treatment induces expression of the aconitate decarboxylase (ACOD1) in differentiating osteoclasts, which increases succinate levels. The initially high expression of ACOD1 decreases towards the end of differentiation when the levels of the desuccinylase SIRT5 increase. Succinylation of citrate synthase (CS) was detected exclusively in stimulated
Dayoung Yu+7 more
wiley +1 more source
Myelin is a multilayered proteolipid membrane in the nervous system. The lipid membranes are held together by specific proteins, and here, we studied three such proteins—P0, MBP, and P2. Our experiments show that the three proteins may act in synergy at the molecular level, while they also compete for lipid membrane surface binding.
Oda C. Krokengen+9 more
wiley +1 more source
Nonvesicular lipid transfer drives myelin growth in the central nervous system
Oligodendrocytes extend numerous cellular processes that wrap multiple times around axons to generate lipid-rich myelin sheaths. Myelin biogenesis requires an enormously productive biosynthetic machinery for generating and delivering these large amounts ...
Jianping Wu+10 more
doaj +1 more source
Sex‐dimorphic gene regulation in murine macrophages across niches
In this study, we perform a meta‐analysis of new and publicly available RNA‐seq datasets from male and female mouse macrophages across eight niches to identify conserved sex‐dimorphic gene expression patterns. We found that three sex chromosome‐linked genes are always differentially expressed between males and females: Ddx3y, Eif2s3y and Xist. However,
Cassandra J McGill+4 more
wiley +1 more source
Mind the GAPS: Glia associated with psychological stress
Abstract Glial cells are an integral component of the nervous system, performing crucial functions that extend beyond structural support, including modulation of the immune system, tissue repair, and maintaining tissue homeostasis. Recent studies have highlighted the importance of glial cells as key mediators of stress responses across different organs.
Niklas Blank+4 more
wiley +1 more source
Proximal node (subcarinal node) from a patient with lower‐lobe lung cancer. The complementary distribution was seen between CD68‐positive macrophages and CD169‐positive cells, and the latter tended to exist with DCsign‐positive cells. The island‐like appearance of the cortex was seen in the nodes.
Masaya Aoki+5 more
wiley +1 more source
Proteomic Profiling of Cerebrum Mitochondria, Myelin Sheath, and Synaptosome Revealed Mitochondrial Damage and Synaptic Impairments in Association with 3 × Tg-AD Mice Model. [PDF]
Shen L+11 more
europepmc +1 more source