Results 201 to 210 of about 53,137 (327)

Ultrastructure of astrocytes using volume electron microscopy: A scoping review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A complete overview on astrocyte ultrastructure with volume electron microscopy. The morphology of astrocytes under physiological and pathological conditions plays a role in brain homeostasis, synaptic activity and structural support, but their morphological complexity and heterogeneity are still poorly quantified.
Vanessa Chiappini   +7 more
wiley   +1 more source

Individual neuronal subtypes control initial myelin sheath growth and stabilization. [PDF]

open access: yesNeural Dev, 2020
Nelson HN   +9 more
europepmc   +1 more source

Saltatory axonal conduction in the avian retina

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Intraretinal axonal spike conduction was studied across multiple avian and mammalian species using high‐resolution multielectrode arrays. On the electrode array, saltatory axonal spike conduction was readily apparent and distinguishable from non‐saltatory conduction.
Christoph T. Block   +5 more
wiley   +1 more source

Glia Preserve Their Own Functions While Compensating for Neighboring Glial Cell Dysfunction

open access: yesGlia, Volume 73, Issue 12, Page 2427-2444, December 2025.
Main Points When cortex glia lose their interactions with neuronal cell bodies, all neighboring glia infiltrate the region to clear extra neuronal corpses. Even while compensating tor nearby glial dysfunction, glia maintain their own phagocytic Tunctions.
Allison N. Beachum   +13 more
wiley   +1 more source

Macrophage Targeting Protects Nerve Structure and Improves Muscle Innervation in a Mouse Model of Charcot‐Marie‐Tooth 2J

open access: yesGlia, Volume 73, Issue 12, Page 2369-2385, December 2025.
Main Points Hemizygous POT124M mice develop a late‐onset axonopathy at 18 months of age. Pharmacological macrophage targeting with PLX5622 prevents distal axon degeneration in POT124M mutant mice and mitigates motor impairment. ABSTRACT In several previous studies, we have shown that macrophage targeting with the CSF‐1 receptor specific kinase (c‐FMS ...
Dennis Klein   +8 more
wiley   +1 more source

Neuroaxonal Dystrophy With Osteopetrosis Associated With a Novel Biallelic Nonsense Homozygous Variant in BORCS5

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Neuroaxonal dystrophy (NAD) with osteopetrosis syndrome (OMIM # 600329) was first reported in a consanguineous Moroccan Jewish family. However, to date, no genetic variant has been linked to this disease. We report on sibs, born to consanguineous Pakistani parents identified prenatally with cerebral ventriculomegaly and agenesis of the corpus ...
Yael Fisher   +6 more
wiley   +1 more source

AAV‐Based Intracerebral Administration of BDNF Promotes Myelin Repair and Cognitive Improvement After Cuprizone‐Induced Demyelination

open access: yesGlia, Volume 73, Issue 11, Page 2189-2205, November 2025.
Main Points AAV‐BDNF improves cognitive performance after cuprizone‐induced demyelination. BDNF promotes OPC maturation and enhances remyelination in the corpus callosum. Mitochondrial integrity is preserved through reduced swelling and improved morphology.
Yousra El Ouaamari   +14 more
wiley   +1 more source

Reduced Accumulation Rate and Morphological Changes of Newly Generated Myelinating Oligodendrocytes in the Corpus Callosum of Aged Mice

open access: yesGlia, Volume 73, Issue 11, Page 2322-2334, November 2025.
Main Points Newly generated myelinating oligodendrocyte accumulation is decreased in the corpus callosum of aged mice. Morphological changes of newly generated myelinating oligodendrocytes in aged mice: greater height, shorter and fewer myelin sheaths.
Sasikarn Looprasertkul   +3 more
wiley   +1 more source

Health Information Avoidance and eHealth Literacy in Patients With Multiple Sclerosis: A Cross‐Sectional Correlational Study

open access: yesHealth Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Information avoidance refers to deliberately evading or delaying access to freely accessible but undesired information, and eHealth literacy refers to people's capability to comprehend, assess, find, and use health knowledge derived from electronic sources.
Leila Mobasher   +4 more
wiley   +1 more source

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