Results 201 to 210 of about 48,603 (346)

A reaction-diffusion model for relapsing-remitting multiple sclerosis with a treatment term [PDF]

open access: yesarXiv
We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines, consumption of myelin sheath due to anomalously activated lymphocytes and its restoration by oligodendrocytes ...
arxiv  

Gall responses to drying habitats: Insights from the community of galling herbivores associated with the superhost Caryocar brasiliense Cambess. (Caryocaraceae)

open access: yesPlant Biology, EarlyView.
Drying processes in the Brazilian palm swamps or Veredas, impact the gall community in adjacent vegetation by reducing the abundance of more sensitive galls, while more resilient galls acclimate to increased dryness by developing thicker protective tissues. Abstract Galls are new plant organs formed in response to the stimuli of gall‐inducing organisms,
I. S. Fernandes   +2 more
wiley   +1 more source

Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research

open access: yesVeterinary Dermatology, EarlyView.
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki   +1 more
wiley   +1 more source

Microelectrode recordings from the human cervical vagus nerve during maximal breath‐holds

open access: yesExperimental Physiology, EarlyView.
Abstract Voluntary breath‐holds can be sustained for a long time following training, but ultimately, regardless of duration, the asphyxic break‐point is reached and the apnoea terminated. The physiological changes occurring during the apnoea include a marked increase in sympathetically‐mediated vasoconstriction in non‐essential organs, such as skeletal
Vaughan G. Macefield   +7 more
wiley   +1 more source

The glia‐immune network: Astrocytes and oligodendrocytes as microglial co‐ordinators in health and disease

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The glia‐immune network involves the communication(s) of glia via immune signalling pathways. In neuro‐homeostasis these pathways have been shown to modulate key processes such as synaptic pruning and myelination. The dynamics of these processes is critical to CNS function.
Verity F. T. Mitchener   +2 more
wiley   +1 more source

Individual neuronal subtypes control initial myelin sheath growth and stabilization. [PDF]

open access: yesNeural Dev, 2020
Nelson HN   +9 more
europepmc   +1 more source

Ultrastructure of astrocytes using volume electron microscopy: A scoping review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A complete overview on astrocyte ultrastructure with volume electron microscopy. The morphology of astrocytes under physiological and pathological conditions plays a role in brain homeostasis, synaptic activity and structural support, but their morphological complexity and heterogeneity are still poorly quantified.
Vanessa Chiappini   +7 more
wiley   +1 more source

Natural History and Diagnostic Findings in an Adult Man Diagnosed With Attenuated Krabbe Disease

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 7, July 2025.
ABSTRACT Krabbe disease (KD), or globoid cell leukodystrophy, is a rare autosomal recessive lysosomal storage disorder caused by a deficiency in galactocerebrosidase (GALC), leading to psychosine (galactosylsphingosine) accumulation and myelin damage.
Eamon P. McCarron   +8 more
wiley   +1 more source

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